Exam 1 Flashcards
1
Q
Vd
A
Dose/Conc
2
Q
CL
A
K * Vd
3
Q
t1/2
A
0.693/k
4
Q
CL
A
Dose/AUC
5
Q
AUC
A
Trapezoid 1/2(A+B)h + Clast*k
6
Q
C (zero order)
A
C = C0 x -kt
7
Q
C (first order)
A
C = C0 x e^-kt
8
Q
Rate of elimination
A
Clearance x concentration
9
Q
K value from graph
A
slope = (lnY2 - lnY1) / (x2-x1)
10
Q
2 compartment Phases
A
- Exponential distribution phase
2. Linear terminal phase
11
Q
K in terms of slope
A
K = -2.303*slope or slope = -k/2.303
12
Q
AUC in terms of Cp0 and K
A
AUC = Cp0/K
13
Q
1 mg/L =
A
10 ug/mL
14
Q
if x = a^y, logx(a)
A
logx(a) = y
15
Q
lnX in terms of logx
A
2.303 * logx
16
Q
ln(e^x)
A
x
17
Q
ln(e^-x)
A
-x
18
Q
log x * y =
A
log x + log y
19
Q
log x/y =
A
log x - log y
20
Q
1/e^x =
A
e^-x
21
Q
K in terms of clearance
A
Cl / Vd
22
Q
primary pk parameters
A
CL and Vd
23
Q
fe
A
U/Dose = CLr/CLtotal = ke/k
24
Q
LD
A
C0 * Vd
25
Q
Cnmax
A
Cp0 * Rac
26
Q
Cnmin
A
Cnmax * e^-k*t
