Exam 1 Flashcards

1
Q

Vd

A

Dose/Conc

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2
Q

CL

A

K * Vd

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3
Q

t1/2

A

0.693/k

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4
Q

CL

A

Dose/AUC

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5
Q

AUC

A

Trapezoid 1/2(A+B)h + Clast*k

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6
Q

C (zero order)

A

C = C0 x -kt

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7
Q

C (first order)

A

C = C0 x e^-kt

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8
Q

Rate of elimination

A

Clearance x concentration

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9
Q

K value from graph

A

slope = (lnY2 - lnY1) / (x2-x1)

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10
Q

2 compartment Phases

A
  1. Exponential distribution phase

2. Linear terminal phase

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11
Q

K in terms of slope

A

K = -2.303*slope or slope = -k/2.303

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12
Q

AUC in terms of Cp0 and K

A

AUC = Cp0/K

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13
Q

1 mg/L =

A

10 ug/mL

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14
Q

if x = a^y, logx(a)

A

logx(a) = y

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15
Q

lnX in terms of logx

A

2.303 * logx

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16
Q

ln(e^x)

A

x

17
Q

ln(e^-x)

A

-x

18
Q

log x * y =

A

log x + log y

19
Q

log x/y =

A

log x - log y

20
Q

1/e^x =

A

e^-x

21
Q

K in terms of clearance

A

Cl / Vd

22
Q

primary pk parameters

A

CL and Vd

23
Q

fe

A

U/Dose = CLr/CLtotal = ke/k

24
Q

LD

A

C0 * Vd

25
Q

Cnmax

A

Cp0 * Rac

26
Q

Cnmin

A

Cnmax * e^-k*t