EXAM 1 Flashcards
Form, locale, and relationship of body parts
Anatomy
How body works to carry out necessary life function
Physiology
Seven Necessary Life Functions
Maintaining boundaries, Movement, Responsiveness, Digestion, metabolism, Excretion, Reproduction
Separation between internal and external environments
Maintaining boundaries
Ability to respond to stimuli
Responsiveness
Muscular system allows movement i.e. skeletal, cardiac, smooth muscle
Movement
Breakdown of ingested food
Digestion
All chemical reactions that occur in the body
Metabolism
Removal of metabolic and digestive wastes i.e. urea, CO2, feces
Excretion
Division of cells, reproduction of offspring
Reproduction and Growth
Why have organ systems?
Organ systems serve cells and supply survival needs
What are the 6 survival needs?
Nutrients, Water, Oxygen, Appropriate amounts, Appropriate atmospheric pressure, Normal body temperature
Integumentary system functions
Protects tissue from injury, desiccation, contains sensory receptors, glands
Integumentary system organs
Skin, hair, nails
Skeletal system functions
Encases and supports organs, provides leverage for skeletal muscles, forms blood cells
Skeletal system organs
Bones, joints, cartilage
Hematopoiesis
Production of blood cells
Muscular system functions
Allows manipulation of environment, locomotion, expression, movement of fluids, posture, heat
Muscular system organs
Skeletal, cardiac, smooth
Nervous system functions
Coordinator, responds to internal and external changes via muscles and glands, memory, interpreter, command center
Nervous sytem organs
Brain, spinal cord, nerves
Endocrine system functions
Regulates processes such as growth, reproduction, metabolism via hormones
Endocrine system organs
Ovary, testis, adrenal gland, pancreas, thymus, thyroid, pineal gland, pituitary gland
Cardiovascular system functions
Pumps blood, transports O2, CO2, hormones, clotting factors, chemical precursors, urea, antibodies, carrier proteins, blood cells, enzymes
Cardiovascular system organs
Blood vessels, heart
Lymphatic/Immune system functions
Picks up and returns fluid leaked from blood vessels, houses lymphocytes, disposes of debris, foreign substances, abnormal growths
Lymphatic/Immune system organs
Red bone marrow, thymus, lymphatic vessels, lymph nodes, spleen
Respiratory system functions
Ventilation, respiration, supply blood with O2 and removal of CO2, pH balance, thermoregulation, speech
Respiratory system organs
Lungs, trachea, larynx, pharynx, diaphragm, nasal/oral cavity
Digestive system functions
Ingestion, digestion, absorption, elimination
Digestive system organs
Oral cavity, esophagus, liver, stomach, small and large intestine, rectum, anus
Urinary System functions
Elimination of nitrogenous wastes from body, regulates water, electrolyte and acid base balance of blood
Urinary system organs
Kidneys, ureter, urinary bladder, urethra
Male reproductive system functions
produces sperm and sex hormones, delivers sperm to female reproductive tract
Male reproductive system organs
Prostate, penis, testis, scrotum, ductus deferens
Female reproductive system functions
Produces oocytes and sex hormones, provides site for fertilization, implantation, and fetal development, produces milk
Female reproductive system organs
Uterus, ovary, fallopian tubes, mammary glands
Maintenance or relatively stable internal conditions despite continuously changing environment
Homeostasis
Three components of homeostasis
Receptor, control center, effector
Receptor
Monitors environment and detects stimuli
Control Center
Receives input from receptor, determines set point at which variable is maintained and appropriate response
Effector
Receives output from control center and provides means to respond
Affarent
Toward control center/CNS, sensory
Efferent
From control center/CNS, motor
Negative Feedback
Rate decreases and product increases, reduces or shuts off process
Negative Feedback examples
Blood glucose, blood pressure, blood calcium, thermostat
Positive Feedback
Production increases and product increases
Positive Feedback examples
Blood clotting, labor contractions, pepsinogen
Superior
above, toward head or upper part
Inferior
below
Anterior
Front, toward front of body
Posterior
Back, toward back of body
Medial
Toward midline of body
Lateral
Away from midline
Intermediate
In between
Proximal
Toward origin of body part, or point of attachment of a limb to the body of trunk
Distal
Further from trunk
Superficial
External, toward body surface
Deep
Internal, away from body surface
Axial
Head, neck, torso
Appendicular
Limbs
Frontal
Forehead
Orbital
Eye
Nasal
Nose
Oral
Mouth
Mental
Chin
Cervical
Neck
Sternal
Center of chest
Axillary
Armpit
Mammary
Nipples
Umbilical
Abdominal
Inguinal groin
Pelvic
Genital
Pubic
Acromial
Shoulder
Brachial
Arm (upper)
Antecubital
Inside of elbow
Antebrachial
Forearm
Carpal
Wrist
Manus
Hand
Palmar
metacarpal, palm
Pollex
Thumb
Digital
Fingers
Coxal
Hip
Femoral
Thigh
Paterllar
Knee
Crural
Shin (anterior leg)
Fibular
Side of leg/shin
Tarsal
Ankle
Metatarsal
Most of toes
Hallux
Big toe
Otic
Ear
Occipital
Back of head
Olecranal
Posterior elbow
Popliteal
Posterior thigh
Sural
Calf
Calcaneal
Heel
Plantar
Underside of foot
Pedal
Foot
Scapular
Dorsal or back shoulder
Vertebral
Midline of back
Sacral
Tailbone
Lumbar
Lower back
Gluteal
Butt
Perineal
Between genitals and anus
Sagittal
Divides left and right
Frontal
Divides anterior and posterior
Tranverse
Divide superior and inferior
Types of Body cavities
Dorsal and Ventral
Coela
Internal cavities
Thoracic cavity organs:
Heart and lungs
Thoracic cavities:
Superior mediastinum, pleural cavity, pericardial cavity within mediastinum
Cranial cavity organs:
Brain
Vertebral cavity organs:
Spinal cord
Pelvic cavity organs:
Urinary bladder, reproductive organs, rectum
Abdominal cavity organs:
Digestive system
Parietal serosa
Lines internal body cavity walls, superficial to visceral serosa
Visceral serosa
Covers internal organ, deep to parietal serosa
Cavity most vulnerable to trauma
Abdominal cavity because walls are formed by muscle only
What happens when Serious membranes become inflamed
Smooth layers become rough and stick together
Study of tissues
Histology
Steps of preparing slides
Fix, Section, Stain
Step 1: Fix
Preserve with solvent
Step 2: Section
Cut into slices thin enough to transmit light or electrons
Step 3: Stain
Enhance contrast using colored dye or heavy metal coatings
Function of epithelial tissue
Forms boundaries between different environments, filters, absorbs, protects, secretes
Characteristics of epithelial tissue
Regneration, Avascular (innervated), Specialized contacts, Supported by connective tissues, Polarity
Apical surface
Upper free side, can have microvilli
Basal surface
Lower attached side, attached to basal lamina
Basal lamina
Adhesive sheet, apical most surface of basement membrane
Basement membrane
Basal surface, Basal Lamina, Reticular Lamina. Resists stretching and tearing
Specialized contacts
Gap junctions, Tight junctions, Desmosomes
Regeneration
Stimulated by loss of apical -basal polarity
First name: simple
absorption, secretion, filtration due to thin layer
First name: stratified
Multiple layers, protection due to multiple layers
Second name: squamous
flattened, scale like
Second name: cuboidal
box like, cubed
Second name: columnar
tall, column like
Simple squamous epithelium
Kidney, lungs
Endothelium: lining of lymphatic vessels, blood vessels, heart
Mesothelium: serosae in ventral body cavity
Simple cuboidal epithelium
Kidney tubules, ducts and secretory portions of small glands such as ovary surface
Simple ColuMnar epithelium
Absorption and secretion of mucus, enzymes, and other substances
Ciliated: bronchi, uterine tubes, uterus
Non-ciliated: digestive tract (stomach to rectum), gallbladder
Pseudostratified ColuMnar epithelium
Ciliated: trachea, upper respiratory tract
Non-ciliated: sperm carrying ducts
Non-keratinized stratified squamous epithelium
Moist linings such as vagina, esophagus, mouth
Keratinized stratified squamous epithelium
SKIN! or epidermis
Transitional epithelium
Hollow organs or organs made for stretching such as bladder, urethra, ureters
Ductless glands
Endocrine. secreted into interstitial fluid
Unicellular or multicellular gland with ducts
Exocrine
Unicellular exocrine glands produce
Mucin
Unicellular exocrine glands contain these cells:
Goblet cells and mucous cells
Unicellular exocrine glands found in:
Intestinal and respiratory tracts
Multicellular exocrine glands are composed of:
Duct, secretory unit, connective tissue for blood and nerve fibers supplying
Simple tubular multicellular exocrine glands
Unbranched. can be found in intestinal and stomach gland
Compound tubular multicellular exocrine gland
Duct branches. can be found in small intestine
Simple alveolar multicellular exocrine gland
Sebaceous gland
Compound alveolar multicellular exocrine gland
Mammary gland, salivary gland
Tubular
Secretory cells form duct
Alveolar
Secretory cells form sac
3 modes of secretion for secretory glands
Holocrine, Apocrine, Merocrine
Merocrine
Products secreted by exocytosis ex: sweat, pancreas
Holocrine
Products accumuluate within then rupture. PIMPLE
Apocrine
Accumpulates products within, but only apex ruptures. ex: breast milk
Connective tissue function
Bind, support, protect, store, transport
Is bone vascular?
Yes
Is cartilage vascular?
No
3 common characteristics of connective tissue?
Common embryonic origin, varying degree of vascularity, extracellular matrix
3 structural elements of connective tissue
Ground substance, fibers, cells
Ground substance
Material that fills space between cells that is made up of (ICP)
Interstitial fluid, cell adhesives proteins, proteoglycans
3 types of fibers
Collagen, elastic, reticular
Collagen fiber
Provides strength, toughness, most abundant
Elastic fiber
Long, thin, branched. Allow for stretch
Reticular fiber
Short, fine, highly branched. allow for stretch
Immature cartilage cells
Chondroblasts
Immature connective tissue cells
Fibroblast
Immature bone cells
Osteoblast
Cell in bone marrow
hematopoietic stem cells
Mast cells
White blood cells that initiates inflammatory response
Macrophage
Phagocytize dead cells, detect debris
Loose Areolar Connective tissue function
Wraps and cushions organs, supports and binds, anchors skin
Loose Areolar Connective tissue is found in
Under epithelia ie lamina propria, surrounds capillaries
White blood cells roam due to open space in
Loose Areolar Connective tissue
Loose Adipose Connective tissue function
Insulates, fuel reserve, protects and supports organs
Loose Adipose Connective tissue is found in
Behind eyeballs, within abdomen, breasts, subcutaneous tissue (cellulite aka fat cells)
Loose Reticular Connective tissue function
FIBROBLAST. supports reticular cells, mast cells, macrophages, and other white blood cells around internal skeleton. Provides housing for white blood cells
Loose Reticular Connective tissue found in
Lymphoid organs such as spleen, bone marrow, lymph nodes
Dense Regular Connective tissue function
Strength (COLLAGEN), FIBROBLAST, withstanding stress
Dense Regular Connective tissue found in
Tendons, ligaments, aponeuroses
Dense Regular Connective tissue is
Parallel collagen fibers and fibroblasts
Dense Irregular Connective tissue function
Resisting tension in many directions
Dense Irregular Connective tissue found in
Dermis, joint capsules, fibrous covering, submucosa of digestive tract
Dense Elastic Connective tissue function
Allows recoil after stretching, flow of blood through arteries and lungs
Dense Elastic Connective tissue found in
Wall of large arteries, ligaments in vertebral column, bronchial tubes
Cartilage is
Matrix secreted by chondroblasts
Chondroblasts are found in
Lacunae
Chondroblasts are made up of
80% water, collagen fibers, hyaluronic acid, chondroitin
Hyaline Cartilage function
Supports and reinforces, cushion, resists stress
Hyaline Cartilage found in
Embryonic skeleton, ends of long bone, ribs, cartilage of nose, larynx and pharynx
Elastic Cartilage function
Maintains shape while allows flexibility
Elastic Cartilage found in
Ear and Epiglottis
Fibrocartilage function
Compress shock, strength
Fibrocartilage found in
Pubic symphysis, discs of knee and intervertebral discs
Loss in flexibility and cushioning means
Cartilage can ossify or become bony
When avascular cartilage loses ability to divide…
Injuries heal slowly
Osseous tissue function
Supports, protects, stores calcium and fat, marrow inside bones is site for hematopoiesis production
Blood function
Transport respiratory gases, nutrients, and waste
3 types of membranes
Serous, mucus, cutaneous
Skin is
cutaneous membrane
Cutaneous membrane is different because it is
dry
Mucous membrane found in
Body cavities that are open to exterior such as respiratory, urogenital, digestive tract
Serous membranes found in
Closed ventral body cavities
3 names for serous membranes
Pericardium, peritoneum, pleurae
2 types of tissue repair
Regeneration and fibrosis
Steps in tissue repair
- inflammation
- organization restores blood supply
- Regeneration and fibrosis effects permanent repair
Step 1 of tissue repair (inflammation)
Release of inflammatory chemicals that allows clotting and scabbing
Step 2 of tissue repair (organization)
Clot replaced with granulation tissue, fibroblasts bridge wound site, and regeneration of epithelium begins
Step 3 of tissue repair (permanent repair)
Scab detaches, fibrous bridge matures, and contracts while epithelium thicken and starts to resemble adjacent tissue
Regenerate well:
Epithelial tissue, areolar connective tissue, bone, dense irregular connective tissue, blood forming tissue
Regenerate moderately:
Smooth muscle, dense regular connective tissue
Do not regenerate
Cardiac muscle and nervous tissue of brain and spinal cord
Keratinocytes
Produce keratin
Melanocytes
Spider shaped cells that produce melanin. protect from UV damage
Dendric or Langerhans cell
Star shaped macrophages that patrol deep epidermis. Activators of immune system
Merkel cells
Sensory receptors that sense touch
Stratum Basale function
Attaches to dermis, contains single row of daughter cells that actively divide producing 2 daughter cells
Takes ___ days to reach surface from basale layer
25-45 days
Melanocytes are___ percentage of cells
10-25%
Stratum basale contains these 3 cells
Melanocytes, Merkel, and dendritic cells
Stratum Spinosum function
Resists tension and pulling, contain web like system of intermediate pre-keratin filament
Appear spikey once dessicatied:
Keratinocytes
Dentritic cells are most abundant in
Stratum spinosum
Stratum granulosum function
Beginning of keratinization, cells flatten and organelles begin to disintegrate, cells above stratum granulosum die because they are too far from dermal capillaries
Keratohylaine granules
help form keratin fibers in upper layers
Lamellar granules of glycolipids
prevent water loos with tight junctions
Stratum lucidum function
Found only in thick skin such as palms and soles. 2-3 rows of clear, flat, dead keratinocytes
When stratum lucidum not present, keratinohyaline granules begin to aggregate in
Stratum corneum
Stratum corneum function
Keratin, plasma membranes, tight junctions, glycolipids ensure minimum abrasion, penetration, and water loss
3/4 of epidermis is
Stratum corneum
How many cells are sloughed every minute
about 50,000 cells
Two layers of dermis
Papillary and reticular
Dermis contains
Hair follicles, oil glands, sweat glands, nerves, blood vessels, lymphatic vessels
Papillary layer is
Superficial areolar connective tissue (thin)
Dermal papillae send
fingerlike projections into epidermis
Fingerprints
Dermal ridge of papillary layer. Friction ridges and openings of sweat glands/ducts
Meissner’s Corpuscle
Touch receptors
Reticular layer is
80% of dermal thickness
Reticular layer is what tissue?
Dense irregular connective tissue
Cutaneous Plexus
Network of blood vessels between reticular and hypodermis
Flexure lines
Folds near joints where dermis is tightly secured to deeper structures. Visible on hands, wrists, fingers, soles, toes
Dermal tears that leave silvery white scars are called
Striae or stretch marks
Short term trauma can cause blisters that seperate
epidermis and dermis
3 components of skin color
Melanin, carotene, and hemoglobin
Melanin is only found in
Deeper epidermal layers
All humans have same amount of melanocytes but what differs?
Form, retainment, and amount of melanin
Carotene accumulates in
Stratum corneum and hypodermis
Carotene can be converted in vitamin A which helps with
Vision and epidermal health
Hemoglobin in skin is caused by
red blood cells in dermal capillaries
Excessive sun exposure causes __ to clump, causing skin to become more leathery
elastic fibers
UV alters DNA which causes
skin cancer
UV destroys folic acid which is
necessary for DNA synthesis
Photosensitivity is
increased response to sun. ex: antibiotics, antihistamines, perfumes, and detergents
Cyanosis
Blue skin, poorly oxygenated hemoglobin
Erythemia
Redness, fever, hypertension, inflammation, allergy
Pallor
Blanching or pale color, anemia or low blood pressure
Jaundice
Yellow, liver disorder or bile accumulates
Bronzing
Inadequate steroid hormones or pituitary gland tumors
Bruises
Hematoma, clotted blood under skin
Cleavage lines
natural orientation of collagen fibers in dermis
Arrector pilli is responsible for
Goosebumps and forcing sebum out
Arrector pilli is a
smooth muscle attached to follice
Sweat glands also called
Sudoriferous glands
Sweat glands are found on all surfaces of skin except
nipples and part of genitalia
Sweat glands regulated by
sympathetic nervous sytem
Two types of sweat glands
Eccrine and apocrine
Eccrine sweat glands are most numerous on
palms, soles, forehead
Eccrine sweat glands are induced by
heat or emotions
Are eccrine sweat glands functional at birth?
Yes
Are apocrine sweat glands functional at birth?
No but they are present. functional at puberty
Is eccrine or apocrine larger?
Apocrine
Eccrine glands connect and empty to
Pore
Apocrine sweat glands connect and empty to
Hair follicle
Two types of apocrine sweat glands?
Ceruminous (sebum, ear wax, sticky barrier) and mammary
Sebum is made out of
Lipids and cell fragments
Sebum is needed for
lubrication of hair and skin, prevention of water loss, bactericidal
Sebaceous glands are
branched alveolar
Cerumin is
apocrine sweat, sebum, dead skin, bacteria
Function of skin
Protection Body temp regulation Sensation Metabolism Blood reservoir Excretion via sweat
Three types of barriers of skin
Chemical, biological, physical
Wounded skin releases
Cathelicidins which prevents infection
Characteristics of acid mantle (low pH)
Dermicin, bactericidal, and defensins
Chemical shield against UV
Melanin
Epidermis full of layers of dead flat cells which contain
keratin and glycolipids
Biological barriers include
Dendritic cells of epidermis, macrophages of dermis, and DNA absorbing UV to convert to heat
Mechanoreceptors respond to
touch, pressure, vibration, stretch
Thermoreceptors respond to
temperature
Photoreceptors respond to
light
Chemoreceptors respond to
chemical like smell, taste, changes in blood chemistry
Nociceptors respond to
pain causing stimuli like extreme heat or cold, excessive pressure, pinch, inflammatory chemicals
Externoreceptors respond to
Stimuli outside of body such as touch, pressure, pain, temp. *most special sense organs
Interoreceptors respond to
Stimuli arising in internal viscera and blood vessels such as tissue stretch, temp changes, chemical changes
Proprioceptors respond to
Stretch in skeletal muscles, tendons, joints, ligaments, etc. they inform brain of one’s movements
Two types of receptor structure
Special sense and general senses
Receptors for special senses
Vision, hearing, equilibrium, smell, taste
Simple receptors of general senses monitor
tactile sensations such as touch, pressure, stretch, vibration, temp, pain, muscle sense
Modified dentritic endings of sensory neurons
Simple receptors of general senses
Non-encapsulated free nerve endings found in
Epithelia and connective tissue
Non-encapsulated free nerve endings respond mostly to
temp, pain, light touch
Non-encapsulated free nerve endings receptors
Thermoreceptors, nociceptors, merkel dics or light touch receptors, hair follicle receptors to detect bending of hair
Encapsulated nerve ending are almost all
mechanoreceptors
Encapsulated nerve endings examples include
Meissners corpuscles, lamellar corpuscles, ruffni endings, muscle spindles, tendon organs, and joint kinesthetic receptors
Meissner’s corpuscles
Detect touch in superficial dermis
Lamellar corpuscles
Detect deep pressure and vibration in deep dermis
Ruffni endings
Detect continuous pressure in dermis
Muscle spindles
Detect muscle stretch in skeletal muscles
Tendon organs
Detect tendon stretch in tendons
Joint kinesthetic receptors
Monitor joint position and motion