Exam 1 Flashcards
Common Barriers to EBP
Individual and System level
- Knowledge/Education
- Low prioritization
- Time
- Resources
- Culture
What is Evidence Based Practice?
“Integration of best research evidence with clinical expertise and patient values”
EBP consists of 3 factors
Evidence
Patient Preferences
Clinician Expertise
How do we integrate best research evidence into patient care?
What do we need to know? (3)
1) Your clinical question
2) How to search for evidence to address clinical question
3) How to appraise evidence for quality
What is research evidence”?
Systemic inquiry to identify “truth”
What is “Best” Research Evidence?
Has a High level of incidence -> when performed well, certain study designs are inherently stronger than others
Characteristics of high quality research evidence
Study results are credible Not due to random chance or Non-random error (bias) or Systematic error
Evidence Pyramid
What are the levels top to bottom?
Systems Summaries Synopses Syntheses Studies
What level of the evidence pyramid does this fall into?
Computerized decision support software and Electronic health records
Systems
What level of the evidence pyramid does this fall into?
Evidence based textbooks, practice guidelines
ex) Dynamed, National Guideline Clearinghouse, UMHS Practice guidelines
Summaries
What level of the evidence pyramid does this fall into?
Pre-appraised Abstracts of Studies & Synthesis
ex) DARE, ACP Journal Club
Synopses
What level of the evidence pyramid does this fall into?
Systematic reviews
ex) Cochrane DSR, PubMed Clinical Queries (systematic review)
Syntheses
Secondary or Pre-appraised
Syntheses
Primary/Original
Studies
What level of the evidence pyramid does this fall into?
Primary Research
ex) PubMed Clinical Queries (Studies)
Studies
Different types of Studies
Randomized Control Trials
Cohort Studies
Case Control Studies
Case reports/Case series
Different types of Syntheses
Meta Analyses
Systematic Reviews
Best to start at the ___ of the pyramid!
Top
Secondary/Pre-appraised studies are those that?
Have multiple articles that are summarized and appraised
Primary/Original studies are those that?
One one study is reported
The reader must appraise study for quality
Appraisal =
Good Quality
Three discrete steps to appraise an article are?
1) Are the results of the study valid?
2) What are the results?
3) How can I apply these results to patient care?
Five Step Evidence Based Nursing Process
PEACE model
Problem Identification Evidence Review Appraise Evidence Care Integration Evaluate Care Integration
Use ___ to identify the Problem in the peace model
PICO
“A consistent systematic way to identify the components of a clinical issue”
PICO
What does PICO stand for?
P - Population
I - Intervention
C - Comparison
O - Outcome
Identify the parts of this PICO question
Among discharged patients, does the receipt of discharge phone calls, compared to no discharge phone calls improve patient experience scores?
P = discharged patients I = receipt of discharge phone call C = no discharge phone call O = improve patient experience scores
Why is PICO useful to you?
Lays the foundation to the 5 step evidence based nursing practice
Helps clarify the actual issue you want to address
Saves time searching - as you can focus your research on evidence that will best address your question
The initial an one of the most difficult steps in evidence based practice
An iterative process
Formulating a PICO question
Question Types (4)
Intervention or therapy
Etiology
Prognosis/Prediction
Meaning
What study design tries to determine which treatment leads to the best outcome?
Ie) Experimental studies (RCT)
Intervention of Therapy
What study design tries to determine the greatest risk factor of a condition?
Ie) Observational studies (eg cohort, case control, observational)
Etiology
What study design tries to determine the progression of a disease?
Ie) Observational studies (eg. cohort, case control, observational)
Prognosis/Prediction
What study tries to understand the meaning of an experience?
Ie) Qualitative research
Meaning
What type of study does this describe?
- Researchers actively introduce intervention or treatment
- Often called clinical trials in medical research
- Can be randomized (RCT) or quasi experimental (when randomization is not performed)
Experimental studies
What type of study does this describe?
- Researchers collect data without intervening or introducing treatments
- Often called non-experimental research
- Can be cohort study, case control study, cross-sectional study, they differ in the time frame of how data are collected
Observational Studies
Types of Observational studies (3)
Cohort
Case Control
Cross Sectional
Time Frames for Cross Sectional study
Exposure and Outcome is in the present
Time Frames for Case Control study
Exposure or No Exposure in the Past
Outcome or No Outcome in the Present
Time Frames for Cohort study
Exposure or No Exposure in the Present
Outcome or No Outcome in the Future
Example of what type of observational study?
Is use of public transport system in NYC associated with covid 19 sx?
Case Control
Outcome = covid 19 -> look back overtime through their travel patterns
What study design would be most appropriate to address this question type?
You work in the inpatient setting and observe suboptimal environmental cleaning practices. You wonder if patients are at increased risk for infection if the individual they are rooming with has an active infection
Observational study
Purpose of a ______ Study
- To explain and predict
- To confirm and validate
- To test theory
- Seeks generalizations
Quantitative
Purpose of a ______ Study
- To describe and explain
- To explore and interpret
- To build theory
- Seeks patterns
Qualitative
What are the methods of data collection for a Quantitative study?
Representative
Large sample
Standardized Instruments
What are the methods of data collection for a Qualitative study?
Informative
Small Sample
Observations, Interviews
What is the form of reasoning in the anaylsis for a Quantitative study?
Deductive
What is the form of th reasoning in the analysis of a Qualitative study?
Inductive (deductive and inductive)
How are findings communicated in a Quantitative study?
Quantitative (numerical) information
Statistics
Aggregated data
How are findings communicated in a Qualitative study?
Qualitative (non-numerical) information
Narratives
Individual quotes
Quantitative Research Concepts
Study purpose/Aim Study population and sampling Variables Measurement Error Hypothesis Testing
States an expectation, a predicted answer to the research question
Research hypothesis
Subset of people in a defined setting
Sample
People in a defined setting
Population
Attributes of patients and clinical events that vary and can be measured
Variables
Independent variable
purported cause or predictor variable
Dependent variable
outcome variable
Extent to which a tool measures the actual condition it is meant to measure
Validity
Consistency of measures over time
Reliability
Bias ie systemic error
“The systematic introduction of error into a study that can distort the results in a non-random way”
Error (2)
Bias (systematic error) Random error (chance)
Null hypothesis
Assume no relationship; akin to “presumed innocence”
P values
likelihood results due to chance
Confidence intervals
contains range of true value
measure of precision
Directional hypothesis
Predicts direction of a relationship
Non-Directional hypothesis
Predicts the existence of a relationship, not its direction
Are Hypothesis proven?
Never proved or disproved
Used only in statistical testing
Expresses the absence of a relationship
Statistical testing performed to provide the probabilistic information to support or reject it
Null Hypothesis
Face Validity
Does an instrument appear to measure phenomenon of interest, weakest form of validity
Content Validity
Extent to which an instrument includes dimensions of the phenomenon under study
ie) scale for measuring pain includes questions about severity and sensation of pain (dull, throbbing, itching)
Construct Validity
Does the instrument perform as expected between similar and dissimilar constructs
Convergent validity
like constructs have similar scores
ie) expect to see similarities between pain and distress scores
Discriminant vailidity
unlike constructs do not have similar constructs
ex) pain scores would differ from intelligence scores
Instrument reliability
The consistency with which an instrument measures the target attribute
Internal consistency
The extent to which all items on an instrument are measuring the same attribute
appropriate for most multi-item instruments
Cronbach’s alpha
Used to assess reliability
Alphas >/- ____ are highly desirable
0.80
Alpha of 1 = total agreement of all items (this is not desirable bc then their just duplicates of each other)
Stability
The extent to which scores are similar on two separate administrations of an instrument
(test, retest- taking your BP twice are they similar)
Measurement
The assignment of numbers to represent the amount of an attribute present in an object or person, using specific rules. Used to operationalize or MEASURE variables in a quantitative study
4 classes of measurement
Nominal
Ordinal
Interval
Ratio
Colors of the rainbow
Race
Gender
Nominal
Likert scale strongly agree to disagree
Letter grades
Ordinal
What class of measurement?
Temperature
Interval
What class of measurement?
Weight
Ratio
Nominal
Classify characteristics into categories, no inherent order
Ordinal
Ranking objects based on their relative standing on an attribute; inherent ordering between categories, but size of intervals not specified
Interval
Objects ordered on a scale that has equal distances between points on a scale (but no absolute zero)
Ratio
Equal distances between score units; there is a rational, meaningful zero
Selection bias
Flawed sample selection procedures; preexisting differences exist between groups being compared; study sample not representative of a larger population
Measurement bias
Biases arise when measures are not valid or reliable
Or are performed inconsistently between study groups
ex) before and after compliance of hand hygiene not measured the same, before by cameras, after by self report
Social desirability bias
Biases that stem from desire to report favorable informatin