Exam 1 Flashcards
What is neuroplasticity?
- Ability of the nervous system to change as circumstances require.
- Instrinsic and extrinsic stimuli trigger reorganization of structure, function and connections
- Can occur at any level of the nervous system
Explaining Cortical mapping
Dermatomes on skin have cortical receptive fields that slightly overlap - the more they overlap the more fine the tactile discrimination
Functional reorganization of the cortex for the hand can be long lasting due to:
- -Changed sensory experience
- -Performance of the hand
- -Local peripheral nerve injury
- -Separation of syndactylies (fingers)
- -UE slings
2 types of CNS plasticity
- Synaptic plasticity
* -Increased/decreased sensitivity
* -Increase/decrease in actual number
- Synaptic plasticity
- Cortical plasticity - size, synapses etc.
- CHANGES ARE ACTIVITY DEPENDENT (CPM won’t work - need active component)
Key points about the reorganization of motor cortex
- -Expands into other areas
- -Reversible
How to increase neuroplasticity
- Must be active - passive stimulation doesn’t work.
- Attention to task important for optimal environment.
Not all neuroplasticity is positive
Tactile function can worsen with certain forms of sensory stimulation (vibration for construction workers)
-Dystonia (form of writer’s cramp) - such a low threshold that it’s easy to activate
Who is Edward Taub and what did he find?
- Edward Taub - one of founders of neuroplasticity
- Found increased cortical representation of the hand of string musicians.
How to make CIMT effective
FARS
- Feedback
- Active
- Reward them and make it achievable
- Self efficacy - let them know why it’s important - what goal are you working towards that they want to achieve?
CIMT: Shaping
How you set up the enviornment
- Explicit feedback to smallest improvement (Knowledge of results)
- Lots of positive feedback/rewards, de-emphasize negative
- Relate shaping task to functional task
- Can use assisted movement with lower functioning patient
Task Practice
- No explicit training
- Functional tasks used
- Limited feedback provided
- GOAL: Use of limb
NOT as effective as shaping approach
Benefits of CIMT
- Overcoming learned nondisuse - reverse mindset of dysfunction
- Cortical reorganization can occur with focused training
When to start aggressive therapy?
- Don’t want to overstress brain as it is healing (first 1-2 weeks post stroke)
- –Basically like overtraining.
Optimizing functional carryovers: Blocked design vs. Random design
Blocked: Initial performance better but worse retention.
(self-efficacy…)
Random exercise and trial and error = better retention and learning (performance initially worse)
Initial inclusion criteria for Modified CI Therapy
- Some finger and wrist movements
- 10° wrist extension
- 10° thumb abduction
- 10° extension of 2 digits
- 50% all stroke patients met this criteria
CIMT summary
Inclusion criteria: cognition intact, some active wrist and finger extension
- Massed practice- 5-6 hrs/day for weeks or less intense, longer duration for months
- Restrained uninvolved UE 5-6 hours/day minimum
- Active, repeated, task-specific practice is critical
- Significant feedback and encouragement
- Consider massed practice bilaterally
- Avoid stressing the CNS too early in acute care— intense therapy is detrimental to the brain because the brain is still healing
- 1 year follow up shows no difference with or without the use of a mitt on unaffected UE
Treatment of focal hand dystonia
Overuse causes cortical smudges
-Minimal repeated practice
Mirror Therapy
using visual input instead of somatosensory input
Movement of intact extremity looks like bilateral movement “trick” brain into activating cortical neurons?
Neurological basis of mirror therapy
Mirror-Neuron system
- Cortical neurons that are activated while moving can also be activated by watching movement
Areas of brain activated by Mirror Therapy
- Superior temporal gyrus
- Pre-motor cortex
- Ipsilateral primary motor cortex
- Integraton with attention (percuneus area)
- Mirror neuron system may connect perceptual and motor areas
Specialized electrical stimulation devices for muscle movement
- Neuro-prostheses - can assist via electrical stimulation to provide many reps.
- Bioness - synchronize electrical pulses to stimulate correct muscles during gait.
- Walkaide - just on fibular nerve
Necessities for Gait
- Biomechanics
* -Appropriate ROM
* -Appropriate Timing
- Biomechanics
- Neuromuscular control
* -Cortical level - initiate gait
* -SC level - SC generator yielding automaticity and reproducibility
* -strength, balance, coordination
- Neuromuscular control
- Cardiovascular stamina
Idea behind Body Weight Support Treadmill Training (BWSTT)
Initiate gait at cortical level and then becomes automatic
Some parts of the neuromotor pathways affecting gait that can malfunction and lead to abnormalities
- Higher centers - dyscontrol over spinal cord outflow
- tone problems, difficulty initiating movement, decreased strength
- Basal ganglia - modulation of movement
- Cerebellum - balance and coordination
- SC lesion - weakness, tone issues