Exam 1 Flashcards
Etiology
Study of the cause of disease
Pathologenesis
The origin and development of a disease
Lesions
Areas of tissue that have been pathologically altered by injury, wound, or infection
Biopsy
the removal of living tissue from the body for diagnostic examination
Diagnosis
identification of an injury or disease
Differential diagnosis
a list of conditions the patient may have based on the symptoms exhibited and the results of the exam
Necropsy
examination of a body after death
sublethal
not quite lethal(death-causing); insufficient to cause death
-Degeneration
Causes of necrosis:
Toxicity, trauma, infections, genetic, altered metabolism, endocrine diseases
Toxicology
study of poisonous or toxic diseases or substances and their effects upon body parts
Ex: Tetanus produces neurotoxin by bacteria
Toxicosis
disease causes by poison
Anticoagulant rodenticides
rodenticides that kill rats by causing abnormal bleeding due to the inability to form a blood clot
coagulopathy
disease of the clotting process
Acetaminophen (Tylenol) Toxicity
Bonds to hemoglobin
- Cats
- They afixiate
- Causes Heinz body anemia
Abdominocentesis
Sampling of free fluid within the peritoneal space.
Apnea
not breathing
Dyspnea
difficulty breathing
Bradypnea
slow breathing
Tachypnea
rapid breathing
hyperpnea
increase in rate and depth of respiration
hypopnea
decrease in rate and depth of respiration
hypoxia
inadequate oxygen to tissues
hypercapnia
high CO2
hypocapnia
low CO2
Anoxia
without oxygen
Aspiration
inhalation of foreign substance into the respiratory tract
Asphyxiation
Suffocation
Atelectasis
incomplete alveoli expanision
Bronchiectasis
dilation of the bronchi
Bronchitis
inflammation of the bronchus
Bronchopneumonia
infection of the bronchi and lungs
COPD
Chronic Obstructive Pulmonary Disease
Cyanosis
blue mucus membranes
Diaphragmatic hernia
hole in the diaphragm
Emphysema
chronic disease causing changes to the wall of the alveloi
Epistaxis
bleeding from the nose
Equine Laryngeal hemiplegia
increased respiratory noises due to degeneration of the laryngeal nerves and muscles
Hemoptysis
coughing up blood
Hemothorax
blood in the chest
Laryngitis
inflammation of the larynx
Larynoplegia
Paralysis of the larynx
Laryngospasm
sudden closure of the larynx
Pharyngitis
inflammation of the pharynx
Phonation
act of producing sound
Pleurisy
inflammation of the pleura
Plueropneumonia
infection of the pleura and lung
Pneumonia
infection of the lung
Pneumothorax
air accumulation in the chest cavity
Polyp
benign growth
pulmonary edema
fluid in the lung tissue
pulmonary fibrosis
fiber formation in the alveoli walls
Pyothorax
puss in the chest
Orthopnea
unable to breath unless in an upright position
Rhinitis
inflammation of the nasal passagses
Rhinopneumonitits
inflammation of the nasal passages and lungs
Rhinorrhea
nasal discharge
Sinusitis
inflammation of the sinuses
Snuffles
upper respiratory infection of rabbits caused by pasturella
Stenotic nares
narrowed nasal passages
Tracheitis
inflammation of the trachea
Tracheobronchitis
inflammation of the trachea and bronchus
URI
upper respiratory infection
Bronchodilators
open airways
- Albuterol
- Beta-adrenergic agonists
- Methyxanthines
- Anticholinergics
Mucolytics
breakdown mucus
- Guaifenesin
- N-acytlcysteine
- Dembrexine
Antitussives
prevent coughing
- Morphine
- Codeine
- Hydrocodone
- Dextromethophan
- Butorphanol
-pnea
breathing
Ox/i, ox/o, ox/y
oxygen
Capn/o
carbon dioxide
Lead poisoning
no simple test exists to detect lead poisoning
Clinical Signs:
- Vomiting
- Diarrhea
- lethargy
- anorexia
- abdominal pain
- regurgitation(due to megaesophagus)
- weakness
- hysteria, extreme anxiety
Nitrate or nitrite poisoning
may occur in ruminants, pigs, and horses ingesting feeds with high concentrations of nitrate.
-Nitrites absorbed from the gut decrease the oxygen-carrying capacity of the blood by degrading hemoglobin to methemoglobin in erythrocytes or methemoglobinemia
Anticaogulant rodenticides
ex: warfarin, diphacinone, pindone
- act by inhibiting metabolism of vitamin K in the body
- coagulopathy hemorrhage(blood does not clot quickly)
Ethylene glycol
- most antifreeze solutions
- can cause serous of fatal toxicosis
- can be detected in whole blood or serum samples by a toxicology lab
Antidote: Fomepizole
- time period to treat is 3 hours for cats and 8-12 in dogs
Classic signs on inflammation
Redness
Heat
Swelling
Pain
Peracute
“very acute”
- 0 to 4 hours
- shock
Acute
4-6 hours to 3-5 days
Subacute
transition between acute and chronic, days to a week
Chronic
persists over a long period of time, weeks to years
What is inflammation?
Vascular and cellular response to trauma
- purpose is to heal injured tissue
- body’s attempt to destroy microorganisms, foreign particles, or dead cells
- protects the body by localizing and removing the injuring agent
Lesion locations
Focal- one spot
Multifocal- multiple foci(spots)
Locally Extensive- one large area that is involved
Diffuse- spread throughtout the organ
Exudation
presence of fluid that leaked out of vessels into tissues and the migration of inflammatory cells into an inflammation lesion
Types of Exudate
- serous
- serosanguinous
- purulent or suppurative
- Fibrinous
- Catarrhal
- pseudomembranous
- Fibrinopurulent
Vascular response
Vasodilation and vascular permeability (leakiness)
-exudation
Pleural Effusion
buildup of fluid in the pleural space
-dyspnea and tachypnea
Pulmonary Edema
fluid buildup in the pulmonary alveolar and interstitial spaces
Hardware’s Disease/ Traumatic reticulopericarditis
Causitive agent: consumption of metal foreign body Clinical Signs: -decreased milk production and fecal output -increased rectal temperature -normal or slightly elevated heart rate -dehydration -rapid and shallow respiration -walk with arched back -grunting
Treatment: surgical removal, antibiotics, and magnet
Johne’s Disease
Causative agent: Mycobacterium avium subspecies paratuberculosis
Clinical signs: silent, subclinical, advanced clinical, profuse watery diarrhea, and weight loss
Diagnosis: Necropsy
Treatment: none
Respiratory Disease
Common clinical signs:
- nasal discharge/congestion
- sneezing
- respiratory stridor
- cough; hemoptysis(coughing up blood)
- pleural effusion(accumulation of excessive fluid in he thoracic cavity)
- dyspnea; respiratory distress
- cyanosis
- anoxia
- facial swelling
- orthopnea(only able to breath in upright position)
- pulmonary edema(accumulation of fluid in the lungs)
Common Treatments:
- establish an airway
- oxygen therapy(ET tube, mask, nasal oxygen lines, oxygen cage)
- minimize stress(sedation, minimal handling)
- thoracentesis/chest tubes with analegesia
- Nebulize(airway humidification/hydration)/Coupage
- Medical therapies(bronchodilators, antibiotics, antifungals etc.)
FEline upper respiratory infection
RESPIRATORY DISEASE Caused by: -Feline Rhinotrachitis virus -Feline Calici virus -Chlamydophila felis( Chlamydiosis:Zoonosis disease)
*acute or chronic disease
Systemic mycoses
RESPIRATORY DISEASE
-Fungal disease from inhalation of spores/wound contamination
Histoplasma capsulatum- associated with bird dropping
Cryptococcus neoformans- pigeon droppings
Strangles
RESPIRATORY DISEASE
Causative agent: Streptococcus equi
Clinical Signs: Sudden fever, mucopurulent nasal discharge, and abscessation of the submandibular and retropharyngeal lymph nodes
Diagnosis: Culture, PCR, or serology
Treatment: Antibiotic therapy and lance and flush
- Maintain under strict isolation protocol(for 6 weeks after recovery)
- modified live virus intranasal vaccine
Guttural Pouch Empyema
RESPIRATORY DISEASE
- sequel to strangles or lymph node abcesses
*Bacterial infection
Guttural Pouch Mycosis
RESPIRATORY DISEASE
fungal infection of the guttural pouch
Heaves
RESPIRATORY DISEASE
- (RAO) recurrent airway obstruction
- allergic airway disease due to airway inflammation, bronchoconstriction, & excessive mucus production
Clinical Signs: cough, nasal discharge, flared nostrils, increased respiratory rate, increased expiratory effort, wheezing, allergic to dust and molds in hay and straw.
-never “cured” of heaves
Inflammatory Airway Disease(IAD)
RESPIRATORY DISEASE
Hyperactive response due to allergens, pollutants, and infectious agents.
-Pathologic changes; (inflammation and excessive mucus production) gas exchange impaired
Clinical Signs: Normal at rest, exercise intolerance, cough, airway secretions
Treatment: treatment of IAD consists of environmental management to decrease exposure to dust and allergens and inhaled or systemic corticosteriods and bronchodilators.
Exercise Induced Pulmonary Hemmorage (EIPH)
RESPIRATORY DISEASE
Cause: Unknown(may be due to rupture of capillary vessels during strenuous exercise)
Clinical Signs: Epistaxis, exercise intolerance, blood seen in airways via endoscopy
-Endoscopy. Cytology via TTW or BAL after exercise.
Treatment: Furosemide, treatment of inflammatory disease if present.
4 forms of Herpes
respiratory, abortion, neonatal, and neurologic disease
Herpes vaccines
- show horses and broodmares
- administered to broodmares during 3rd, 5th, 7th, and 9th month of pregnancy to prevent abortion.
Herpes
RESPIRATORY DISEASE
- Contagious virus
- Clinical signs almost indistinguishable from influenza
- Incubation period 2-10 days
- transmitted by aerosol transmission, respiratory secretions, and fomite transmission
Equine Influenza
RESPIRATORY DISEASE
Causative Agent: Orthomyxoviridae family
Clinical Signs: Fever, anorexia, weight loss, mucopurulent nasal discharge, increased respiratory rates, and retropharyngeal lymphadenopathy
Diagnosis: Presumptive, virus isolation, immunoassay, immunofluorescence, PCR, and antibody detection
Treatment: Supportive
Bacterial Pneumonia & Pleuropneumonia
RESPIRATORY DISEASE
Bacterial Pneumonia due to aspiration of bacteria, with colonization.
Clinical Signs: exercise intolerance, fever, tachypnea, cough, mucopurulent discharge anorexia and chest pain
Diagnostic proceures: Hematology, TTW, thoracic rads
Treatment: Antibiotics, anti-inflammatories, pleural drainage
Bovine Respiratory Disease Syndrome (BRDS)
Syndrome caused by a complex interaction of respiratory viruses, bacteria, and stress.
Viruses:
- Infectious bovine rhinotracheitis (IBR)
- BVD
- Parainfluenza Virus (PI3)
- Bovine respiratory syncytial virus (BRSV)
- respiratory coronavirus
Clinical Signs: depression, standing with head lowered, anorexia, fever, nasal discharge, cough,
BRDS in feedlot cattle is called what?
shipping fever
-mannheimia (pasteurella) haemolytica and sometime P. multocida
Ovine PRogressive Pneumonia (OPP)
RESPIRATORY DISEASE Manifests as: -Progressive respiratory failure -Mastitis ("hard bag") -neurologic signs -arthritis
Clinical Signs: exercise intolerance, open mouth breathing, exaggerated expiratory effect, occasional dry cough.
Atrophic Rhinitis
RESPIRATORY DISEASE
Clinical signs: sneezing, coughing, tear staining, blockage or inflammation of the lacrimal duct, epistaxis, decreased performance, and deformation of the upper jaw.
Glasser Disease
RESPIRATORY DISEASE
Clinical Signs: Fever, depression, difficult breathing, cough, anorexia, and lameness.
-chronic pericarditits & CHF
Treatment: antibiotics
Diagnosis: history, clinical signs, CSF, and cardiac blood or joint culture
other respiratory diseases
- kennel cough.
- pneumonia
- feline asthma
- tracheal collapse
- heartworm disease
- laryngeal paralysis
- Brachycephalic airway disease
abdominocentesis
use of a needle to remove fluid from the abdomen
adenoma
Benign tumor of glandular tissue(small intestine, colon)
ANAPHYLAXIS
acute hypersensitivity reaction
anemia
low red blood cell count
angiopathy
disease of blood vessel
anthrax
bacterial illness. Caused by the bacteria: Bacillus Anthracis. Mainly affect wildlife and livestock.
Aortic thromboembolism (ATE)
A thrombus is formed(typically in the left atrium) and then dislodges and travels through the aorta distally until it reaches an artery.
- usually in cats
- rear leg
- Causes serious pain and paralysis
-can be caused by hypertrophic cardiomyopathy
Apnea
not breathing
ascites
swelling in the abdomen caused by fluid buildup.
-most related to liver disease
asphyxiation
suffocation
aspiriation
inhaling foreign object into the lungs and lower respiratory tract
asthma
airways become inflmaed, narrow, swell, and produce extra mucus making it difficult to breathe
- bronchoconstriction, wheezing, coughing
Atelectasis
complete or partial collapse of a lung or a section (lobe) of lung.
autoimmune disease
The body’s immune system attacks healthy cells.
Basophilia
- blood condition
- high basophil count
emesis
vommiting
endocarditis
inflammation of the inner heart
eosinophilia
high eosinophils
epistaxis
nose bleed
febrile
fever
guttural pouch mycosis
-disease in horses
Caused by a fungus that infects the lining of the guttural pouch
-can cause some deep damage to the arteries and nerves
hardware disease
(Bovine traumatic reticuloperitonitis)
- caused by the ingestion of a sharp metallic object.
- reticulum; can penetrate the lining
Heart failure
can’t pump enough blood to meet the body’s needs
Heaves/
Recurrent airway obstruction)(RAO
-most prevalent lung disease seen in horses.
- equine asthma
- labored breathing
Hematemesis
vomiting blood
hematochezia
bright red blood in the stool
hematoma
collection of blood outside the blood vessels
-causing swelling
hemoptysis
coughing up blood
hepatoma
benign liver cancer
How do anticoagulant rodenticides work?
they stop the ability to clot
-they interfere with vitamin K
hypercapnia
high CO2
hypersensitivity
allergic reaction
hypertension
high blood pressure
hypertrophic cardiomyopathy
thickening of the heart muscle that causes contractions
- can cause ATE in cats
5 signs of inflammationbe able to write them out
- redness
- heat
- swelling
- pain
- loss of function
5 types of white blood cells**be able to write them out*
- Basophil
- Neutrophils
- eosinophils
- lymphocytes
- monocytes
Bovine respiratory disease syndrom(BRDS)(shipping fever)
can be caused by a bacteria, virus, or stress**
-can cause pneumonia
hypotension
low blood pressure
bronchial lavage
medical procedure in which a bronchoscope is passed through the mouth/nose into the lungs and fluid is squirted into a small part of the lung and then collected for examination.
-typically performed for diagnose of lung disease
cachxia
wasting of the body due to severe illness
Cancer caused by the feline vaccine administration
- sarcoma
- feline vaccine related sarcoma
carcinomas
malignant tumor of epithelial cells
cardiac tamponade
compression of the heart caused by fluid collecting in the sac surrounding the heart.
cystocentesis
aspirating urine from the bladder using a needle and syringe
core vaccines for felines
- FCV: feline calicivirus
- FPV: feline panleukopenia virus
- FeLV: feline leukemia virus
- rabies
- FHV1: herpes virus 1
core vaccines for canines
- parovirus
- distemper
- Adenovirus-2
- rabies
cardiomegaly
enlarged heart
cardiomyopathy
disease of the heart muscle
dilated cardiomyopathy
the hearts ability to pump blood is decreased because the hearts main pumping chamber (left ventricle), is enlarged and weakened
diastole
resting period
systole
contracting period
difference between arteries and veins
veins pump blood towards the heart
arteries take blood away from the heart
diseases containing in the EWT/WNV vaccine
- vaccines for horses
- west nile virus, tetanus, western equine encephalitis, eastern equine encephalitis
diseases contained in the DA2PP vaccine
distemper and adenovirus-2
diseases containined in the FVRCP vaccine
calici virus, rhinotracheitis, panleukopenia
dyspnea
difficulty breathing
ecchymosis
spontaneous bruising in large areas
edema
fluid buildup in the tissues
effusion
fluid buildup in the cavities
embolus
blockage; ex: blood clot
hypovolemia
decreased volume of circulating blood
hypoxia
low oxygen level
incidence
ratio of diseased animals to overall population
infarct
tissue death from lack of blood flow
infectious
spread easily
kennel cough
upper respiratory infection in dogs.
- bacterium: Bordatella bronchiseptica followed by canine parainfluenza virus, and lesser extent canine cornavirus
labile
killed by boiling
leiomyosarcoma
malignant tumor of the muscle
leptospirosis
effects the kidneys and liver
-bacterial disease spread through urine
leukocytosis
high white blood cell count
leukopenia
low white blood cell count
mast cell tumor
malignant tumor of the connective tissue
-most common malignant skin cancer in dogs
mediastinum
spot between the lungs.
-heart, esophagus
melena
dark black digestive blood in the stool
morbidity
number of sick animals to overall population
incidence
mortality
how many sick animals that will die
mucoid
fluid made of mucus
mucopurulent
pus/mucus
-green/yellow color
myelomas
malignant tumor of the bone marrow
neutropenia
low neutrophils
neutrophillia
high neutrophils
rhinitis
inflammation of nasal passages.
-mucus discharge/ sneezing
osteomas
benign bone cancer
pancytopenia
ALL low blood cell count
parvo
disease caused by the parvo virus
Symptom: diarrhea, vomiting
parainfluenza
can cause kennel cough
-can affect lower and upper respiratory tracts
pericardial effusion
fluid build up around the heart and pericardial sac.
Causes: cardiac tympanade
pericarditis
inflammation of the pericardium
pericardium
sac around the heart
peritoneal cavity
- abdominal cavity
- potential space between the parietal peritoneum and the visceral peritoneum
petechia
pinpoint bruising
pleura
lining of the chest cavity (thorax)
pleural effusion
fluid buildup in the chest cavity
pleurisy
inflammation of the tissues that line the lungs and the chest cavity
pleuritis
inflammation of the tissues that line the lungs and the chest cavity
-inflammation of pleura
pulmonary edema
fluid in the tissue of lungs
purulent exudate
discharge made up of pus(wbc)
rabies
symptoms: altered behavior, progressive paralysis, death
pyothorax
presence of inflammatory fluid or pus within the chest cavity, which is the area between the lungs and inner walls of the ribs
recurrent airway syndrome (heaves)
- equine asthma
- airway constriction in horses
rhabdomyosarcoma
malignant tumor of the muscle
what does IMHA stand for? be able to write it out
autoimmune hemolytic anemia
What does Tb stand for? be able to write it out
Tuberculosis
sequala
consequence of disease
serous
fluid
-serum
sarcomas
malignant tumors of connective tissue
rhinopneumonitis
equine herpes virus
right AV valve is also known as?
mitral valve
shipping fever is also called ?
bovine respiratory syndrome
-caused by virus, bacteria, STRESS
strangles
abscess in the lymph nodes
tetanus
bacterial infection that causes muscle spasms
(affects the nervous system)
-colstridium tetani
thoracic cavity
chest cavty
thoracentesis
removal of fluid with a needle and syringe from the thoracic(chest) cavity
thrombocytopenia
low thrombocytes
types of vaccines:
live-attenuated, inactivated, recombinant, toxoid
toxoplasmosis
results from infection with the Toxoplasma gondii parasite
vasculitis
inflammation of the blood vessels
vector for borrelia burgdorferi
lyme disease
ticks
vector for eastern equine encephalitis
mosquito
vector for heart worm disease
mosquito
what bacteria causes CIRD
bordatella bronchiseptica–kennel cough
what does CIRD stand for?
canine infectious respiratory disease