Exam 1 Flashcards
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Mature nervous tissue has little capacity to store ______ or _____
oxygen, sugar (glucose)
Mature nervous tissue has little ______ capacity
mitotic
2 different components of the nervous system, broken up by structure
CNS, PNS
CNS is made up of what?
Brain (encephalon), Spinal cord (Medulla spinalis)
PNS is made up of what?
12 cranial nerve pairs, 31 spinal nerve pairs = 86 total nerve trunks and Ganglia
Groups of neuron cell bodies clustered together in the PNS
ganglia
Part of the N.S. that innervates the skeletal musculature “skeletal muscles”
Somatic component of the N.S.
Somatic component is synonymous with…
Voluntary component
Includes both efferent and afferent nerve fibers
Somatic component of the N.S.
The chemical released by the somatic axon endings (cholinergic)
Acetylcholine
2 different components of the N.S. broken up by function
Somatic and Autonomic
Part of the N.S. that innervates the glandular epithelium, smooth, and cardiac musculature
Autonomic (Visceral) Component of the N.S.
The involuntary portion of the N.S.
Autonomic
Parasympathetic subdivision of the visceral component of the N.S. is known as
Vegative
Autonomic component of the N.S. involves ____ and ____ structures
CNS and PNS
The nerves (PNS) that carry efferent parasympathetic fibers are limited to:
Cranial nerves: III, VII, IX, X
Sacral nerves 2, 3, 4
places where we find nerves that carry parasympathetic info is known as a
craniosacral subdivision
Two efferent neurons that are utilized to reach the gland cell or muscle cell involved are the
preganglionic (first) and postganglionic (second)
Autonomic preganglionic (___) neuron is _____
first, long
Autonomic postganglionic (____) neuron is _____
second, short
Preganglionic parasympathetic neurons release
acetylcholine
postganglionic parasympathetic neurons release
acetylcholine
Autonomic component of the N.S. is said to be a _____ system
cholinergic
Fight or flight
Sympathetic subdivision of the visceral component of the N.S.
Neurons of the sympathetic subdivision are located in…
both the CNS and PNS
PNS nerves that carry sypathetic efferent fibers are…
spinal nerves T1 through and including L2
Preganglionic sympathetic neurons are
short
Postganglionic sympathetic neurons are
longer
Preganglionic sympathetic neurons release
ACH
Postganglionic sympathetics neurons release
norepinephrine
Sympathetic subdivision of the Visceral component of the N.S. is said to be an
adrenergic system
In the sympathetic subdivision, exceptions, where ACH is released at the target, are known as:
sweat glands and arrector pili muscles
Slows heart rate / speeds peristalsis / constricts the pupil / constricts respiratory tree
parasympathetic
speeds heart rate / decreases peristalsis / dilates the pupil / dilates respiratory tree
sympathetic
Sympathetic ratio of preganglionic to postganglionic neurons
1:17
Parasympathetic ratio of preganglionic to postganglionic neurons
1:2
Neuron cell bodies in CNS trace origin to
neural tube
neuron cell bodies in PNS trace origin to
neural crest cells
The 3 primary brain vesicles
Prosencephalon (forebrain), mesencephalon (midbrain), and Rhombencephalon (hindbrain)
The 5 secondary Vesicles
Telencephalon, Diencephalon, Mesencephalon, Metencephalon, and Myelencephalon
Prosencephalon gives rise to
telencephalon and diencephalon
Mesencephalon gives rise to
Mesencephalon
Rhombencephalon gives rise to
metencephalon and myelencephalon
The 5 secondary vesicles give rise to
mature structures
Telencephalon gives rise to
cerebral cortex, basal ganglia, and lateral ventricles
Diencephalon gives rise to
Thalamus, Hypothalmus, Pineal Gland, and 3rd ventricle
Mesencephalon (Secondary vesicle) gives rise to
corpora quadrigemina, cerebral peduncles, and cerebral aqueduct (of sylvius)
Metencephalon gives rise to
cerebellum, pons, and 4th ventricle
myelencephalon gives rise to
medulla oblongata, 4th ventricle (continuous with spinal cord)
Brain at birth =
10% of body wt. / uses 50 - 60% of O2
Brain in adult =
2 - 2.5% body wt. / uses 20% of O2
Neuroepithelial cells (stem cells) give rise to
Neuroblast, Ependymal Cells, Glioblast
Neuroblasts give rise to
neurons
Glioblasts (or spongioblasts) give rise to
Astrocytes and oliodendrocytes
Glioblast cells can undergo
mitosis
The functional connective tissue of the CNS come from
glioblast and its derivations
Secrete chemicals that attract or repel migrating neurons
functional connective tissue
What cells help guide neurons
glioblast
It is estimated that in total there are 5 - 10 times as many ____ and _____ as neurons in the adult human brain
astrocytes / oliodendrocytes
Most numerous cell of the adult central nervous system
Astrocytes (stellate shape)
A stroke is most likely cause to move ______ around
astrocytes
Astrocytes are mostly not
mitotic
Protoplasmic astrocytes found in
gray matter
fibrous astrocytes found in
white matter
The primary job of astrocytes
structural support cell
Astrocytes are found between blood vessel capillaries and neuron cell bodies. Those in this position are said to be part of the ________ _______ ______
Blood Brain barrier
Astrocytes store
glucose (glycogen)
Astrocytes form (what) following a CNS injury.
“scar-like” tissue (this is where mobility potential may be of use)
Oligodendrocytes are found in the
white matter
Interfascicular oligodendrocytes form _____ ____ around most CNS neuron axons
myelin sheaths
Perineural oligodendrocytes are unclear but may serve a type of _____ ______ in the CNS
nutrient role
What cells line the central canal and ventricles of the CNS
Ependymal Cells
Most ependymal cells are classified as
simple cuboidal
Ependymal cells secrete CSF and form the
choriod plexus in each ventricle
Is there cilia present in Ependymal cells?
Yes, but NO. At first they are ciliated. but by the time we are adults they are lost.
Tanycytes are found in 1 place
3rd ventricle ependymal cells
Tanycytes are responsible for transporting things from the CSF to
hypophsial portal system
Most common brain tumor
astrocytoma
Most lethal primary brain tumor (more frequent in older people)
Glioblastoma
Most restrictive glioma?
ependymoma (derived from ependymal cells and restricts CSF, Blood flow down, and Intracranial pressure aka ICP is high)
This is mesodermally derived. They arise from fetal macrophages and invade from the bloodstream during embryonic and fetal development
Microglia
Microglia phagocytic function
responsible for clearing dead and damaged tissue and may even wall off damaged areas along with the astrocytes
Microglia also ______ ______ responses within the CNS
mediate immune
HIV infects
microglia
Neuroblast cells show little _____ activity but do undergo _____ / ______ and ______
mitotic, growth/maturation and adaption.
______ and _____ _____ during critical embryonic and foetal stages may cause under/over shooting of designated targets
radiation and alcohol exposure
The neuron is the _____, _____, and ______ _____ of the ner-vous system.
genetic, anatomical, and functional unit
Neurons are classified into ______ and _______
anatomical and physiological
Anatomicallyl neurons are based on _____ and generally designated as ____, _____, and _____
appearance, unipolar, bipolar, and multipolar
Physiologically neurons are based on ______ and _____ and generally designated as _____, _____ and _____
function, position, sensory, motor, internuncial
General sensory neurons in ganglia with one process =
unipolar/pseudounipolar
Special sensory organs (neurons with two processes)
Bipolar
Every neuron will have ____ axon process sending information away from the cell body
ONE
______ neurons have more than 2 processes, they are more in our CNS then anything else
Multipolar neurons
Most common type of neuron
multipolar
Neurons that carry information towards CNS
Sensory
Dendrites carry information
towards cell body
Axon carry information
away from cell body
Neurons that carrying information away from the CNS
motor
Neurons that are located entirely within the CNS structures. They are like messengers or connectors between incoming sensory and outgoing motor neurons. Terms associative or interneuron are sometimes used synonymously
Internuncial
An internuncial neuron that connects equivalent structures on opposite sides of the CNS
Commissural
An internuncial neuron that begins in one structure and terminates in a different structure of the CNS
Projection