exam 1 Flashcards
best binder for drugs
molasses
how to administer oral meds in horses
60cc syringe directly into mouth using a binder facing back of mouth
gap space between teeth
diastema
advantages for needle facing heart
drives into neck if they are jumpy
disadvantages of needle facing the heart
more prone to clostridial infections
IV needle size in horses
18G 1.5inch needle
why is the needle always 1 and a half inches in horse IV
to make sure it is well seeded into the vessel
advantages of needle facing head
easier placement for the human – biggest disadvanage is if the horse moves
biggest issue with perivascular injections
laryngeal hemiplegia and the horse could become a roarer
where to inject in horse neck
middle to upper 1/3 of the neck
making sure to avoid the carotid
how can you tell if you hit the carotid or the jugular
carotid will spew out all the blood
needle size for IM injections
no smaller than 21G 1.5inch needle
what is the max amount that can be injected in the neck of a horse
10-15cc max per site
most common clinical condition and cause of death in ICU horses
endotoxemia
criteria to dx SIRS
need at least 2 of these: leukopenia or >10% bands hyper/hypothermia tachycardia/tachypnea evidence of sepsis in foals
what part of gram - bacteria accounts for the endotoxemia
LPS layer
accounts for the serological difference among bacterial species
polysaccharide O - polar region
responsible for the toxic effect of LPS
lipid A region
hepatic macrophages that are scavengers of endotoxin
kupffer cells
T/F
bloat is a major sign of colic
true
if you have a horse that you treat with banamine and they are not showing clinical signs of pain, but are refluxing?
enteritis
neorickettsia ristcii disease that causes damage to GIT
potomac horse fever
esophageal obstruction that causes GI and resp signs
choke
major cause of reproductive colitis
retained placenta
how many hours do you have before the retained placenta must be out before it is bad
2 hours – treat with oxytocin
excessive conversion of glucose to fat
lipotoxicity – can progress to insulin deficiency
T/F
bacteremia is registered by the adaptive immune response
FALSE – innate
no memory is ever formed
LPS binds to ___
LBP
The LBP binds to ___ on the macrophages
CD14
TLR4 activates what pathways
MyD88 - pro inflam = horses only have this one!!
Trim and Tram - anti inflam
what does MyD88 release
TNF and IL-1 = proinflammatory
vasodilatory substances released by damaged endothelial cells
prostacyclin and no2
which is the initial stage in endotoxemia:
hyper or hypodynamic shock
hyperdynamic is initial stage - with pulmonary vasoconstriction
hypodynamic shock is later and has vasodilation