Exam 1 Flashcards
X-linked trait of a hereditary disease: what is more common, recessive or dominant? women or men?
recessive, men
what is an x-linked disorder that is very severe?
hemophilia
turner’s syndrome
pt. has single X chromosome; monosomy
trisomy
extra copy of one chromosome; 3 copies of chromosome 21 are in each cell
monosomy
Each body cell has a missing chromosome
Most often incompatible with life
polyploidy
Embryo has one or more extra sets of chromosomes
Usually results in early spontaneous abortion
physical char. of monosomy turner’s syndrome
- broad chest, wide spread nipples
- cystic masses either side of neck
- short stature
- kidneys may be joined together
a physiologic change that removes the protective coating from the heads of the sperm
capacitation
a cap on the sperm, small perforations form here to allow enzymes to escape
acrosome
the inner protective layer of the ovum
zona pellicuda
– the outer protective layer of the ovum
corona radiata
when a sperm has penetrated an ovum, both become enclosed in a protective membrane
zona reaction
the fertilized ovum, the single cell formed by union of sperm and egg, 46 chromosomes, all characteristics of new being is established, every genetic feature including sex
zygote
a solid ball of cells within 3 days
morula
a hollow cavity that forms within the cell mast in 4 days, difference of the outer and inner cells
blastocyst
the outer layer of cells surrounding the cavity replacing the zona pellucida (produces HCG), double every 48 hours
trophoblast
occurs 6-10 days after conception, trophoblast burrow into endometrium, some woman experience vaginal bleeding and occurs around time of the missed period
implantation
vascular, finger-like projections extending out from trophoblast into the endometrium, begins to obtain nutrients fro developing ova
chorionic villi
what are the 3 stages of prenatal development?
-preembryonic development, 4th day after conception, embryonic stage
what is the pre-embryonic stage?
1st 14 days
what is the 4th day of conception?
the ZYGOTE enters the uterus with the help of chorionic villi (vascular, finger-like projections extending out of trophoblast & obtains nutrients for developing ova)
what happens during embryonic stage?
15 th day or the 3rd week - 8 weeks - 3cm crown to rump (most critical time in organ development)
what are the 2 main things to know about third stage: embryonic stage?
- most critical time for organ development
- most vulnerable to teratogens
what are the 2 fetal membranes that have to do with the embryo?
chorion & amnion
outer membrane; develops from trophoblast, covers fetal side of placenta
chorion
inner membrane, surrounds fetus; develops from interior cells of blastocyst; develops into fluid sac around the fetus
amnion
Development of specialized structures is controlled by 3 factors
genetic info from parents, interaction between adjacent tissues & timing
drugs in pregnancy: what is category A drugs and giv example
no evidence that it harms fetus (mag. sulfate)
category b:
animal reproduction studies have not demonstrated risk to fetus; no adequate studies done in pregnant women
(prozac, tylenol)
category c:
animal reproduction studies have shown an adverse effect on fetus but no adequate, well-controlled studies have been done in humans; (acyclovir, albuterol)
category d pergnancy drugs
positive evidence of human fetal risk based on adverse reaction data (depacote, tetracyc.)