exam 1 Flashcards
the branch of medicine, policy, and administration that protects populations of people from diseases
public health
intersection of vet medicine and public health
vet public health
T/F
there are less than 70 million food borne disease cases a year in the USA
FALSE – more and 70 mill
T/F
Most foodborne disease agents originate from
animals
TRUE
diseases with animal reservoirs
zoonoses
zoonoses account for what percent of emerging diseases
75%
what was SARS originally
a bat coronavirus
the study of distribution and determinants of disease and other health outcomes in animal populations
epizootiology
what are the three “dynamics” of disease transmission
host
agent
environment
who discovered cholera was spread fecal-orally in londons water supply
john snow - 1849
earliest reports of anthrax
1491BC
who first isolated the bacteria that causes anthrax
robert koch 1879
who had the anthrax vaccine in 1881
pasteur – for sheep goats and cattle
discovered malaria is transmitted by mosquitos
Ronald Ross
discovered yellow fever is from mosquitoes
Walter Reed
T/F
knowing the specific agent is more important than transmission method in disease prevention
FALSE – other way
habitat in which an infectious agent normally lives, grows, multiplies
reservoir
**maintain pathogens over time year to year, generation to generation
three questions to decide if its a reservoir
- naturally infected
- maintain pathogen over time
- can source transmit disease to a new susceptible host
T/F
all sick animals are reservoirs
FALSE
infection doesnt equal disease doesnt equal infectivity
transmission from host to offspring
vertical
pathogens that can cross the placenta
congenital transmission (vertical type)
transmitted during parturition via colostrum
perinatal – vertical type
transmission from reservoir to new host
horizontal
T/F
airborne is a type of direct transmission
TRUE q
any inanimate object that serves to communicate a disease
vehicle
a living organism that serves to communicate a disease
vector
objects that can be contaminated and transmit disease on a limited scale
fomites
microbe is replicating but not enough to be infectious
latent
microbe is replicating but not yet symptomatic
incubation
invasion, not multiplication of an organism
infestation
disease caused by an agent capable of transmission by direct, airborne, or indirect routes from an infected person, animal, plant or a contaminated inanimate reservoir
communicable
disease transmissible from one human/animal to another via direct or airborne routes
contagious
disease caused by the invasion and multiplication of a living agent in/on a host
infectious
what do epidemic curves tell you
– Most probable source of the outbreak
– If the pathogen is contagious
– If the outbreak is ending – or will continue
– Incubation period of the pathogen (sometimes)
– About outliers
Represent the number of new cases of
disease, over time
epidemic curve
common point single source exposure curves
All animals are exposed at once • All are exposed to the same source of infection • Not contagious • Can determine the minimum, average, and maximum incubation time
common source with intermittent exposure curve
- Animals are exposed at different times
- Exposed to the same source
- Incubation period is NOT clearly shown
A situation in which all factors influencing
disease are relatively stable, resulting in little
fluctuation in disease incidence over time
endemic stability
– New cases occur at a regular, usually low, level
– Young individuals may enter the population
– Old individuals die or are removed
Factors that help DETERMINE the probability, distribution, or severity of a disease in an animal or population of animals
determinants
Social Economic Physical environment Person/animal individual characteristics, behaviors, and genetics
primary determinant
a MAJOR contributing factor, usually a
NECESSARY one
secondary determinant
factors that make the disease more or less LIKELY; predisposing or enabling factors
intrinsic determinant
determinants that are internal to the
animal (age, breed, sex, etc.)
extrinsic determinant
determinants that are external to the
animal (housing, medical treatment, etc.)
T/F
primary determinants must always be present for a disease to occur
TRUE
extrinsic factors of an infectious agent
Infectivity • Pathogenicity • Virulence • Immunogenicity • Mutation rate • Resistance
extrinsic factors of the environment
- Demographics
- Climate
- Housing
- Crowding/density
- Diet
- Stress
what can mutations include as far as agent determinants go…
– Increased infectivity within typical hosts
– Ability to infect new species / populations of hosts
– Acquisition of new toxins
– Immune system evasion
All of these host factors are intrinsic/extrinsic??
-Age • Sex & Behavior • Genotype • Breed • Nutrition • Immunity
INTRINSIC
genotype
a term describing the DNA
sequence, or “type”, of an individual
T/F
genetic diseases are entirely determined by genotype
TRUE
T/F
Nutrition has a strong effect on immune
function
TRUE