Exam 1 Flashcards

1
Q

What is the function of the Parathyroid Hormone?

A

Bone formation and resorption. Can increase the recruitment and the activity of osteoclasts.

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2
Q

Most Euchromatic Cells are what? name 4

A

Neurons
Hepatocytes(liver cells)
Pancreatic acinar cells
Sertoli cells

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3
Q

What are the 4 functions of a plasma membrane?

A

communication
intercellular connection
physical barrier
selective permeability

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4
Q

which organelle has Uniparental inheritance?

A

Mitochondria

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5
Q

What are some unique characteristics about Mitochondria?

A
  • they are self-replicating organelles
  • they are uniparental inheritance
  • double membrane=cristae (foldings)
  • not visible under LM
  • atp production
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6
Q

10% buffer formalin is added during which step of tissue processing?

A

Fixation

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7
Q

Which step during tissue processing is where paraffin is introduces?

A

infiltration

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8
Q

what is the resolving power of TEM?

A

0.16-0.18 nm

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9
Q

what are the advantages of SEM?

A

3D images

external structures only

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10
Q

When doing tissue processing what size do the tissues have to be sliced?

A

1-7um

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11
Q

What is the diameter range for intermediate filaments?

A

between 6 and 12nm in diameter. they are between the size of actin and myosin

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12
Q

What intermediate filament stain shows Epithelium?

A

Tonofilaments (cytokeratins)

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13
Q

what intermediate filament stain shows you mesenchymal cells?

A

VIMENTIN

fibroblasts, chondroblasts, osteocytes, macrophages, endothelial cells, vascular smooth muscle cells

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14
Q

What intermediate filament stain shows muscle?

A

Desmine

striated and smooth muscle

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15
Q

what intermediate filament stains shows neurons?

A

Neurofilaments

most but probably not all neurons

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16
Q

What are the four different pigments?

A

melanin
lipofuscin
lutein
hemosiderin

17
Q

Where is lipofusin found and what color is it?

A

neuro, skeletal, cardio
it is the wear and tear pigment
brown

18
Q

Where is hemosiderin found and what color is it?

A

spleen

brown pigment

19
Q

What are some characteristic of Microvilli and where are they located?

A

non-motile
increase surface area for absorption
located in the kidney and intestine

20
Q

What are some characteristics of Cilia and where are they located?

A

motile
longer but less dense
upper respiratory tract

21
Q

what are some characteristics of sterocilia and where are they located?

A

non-motile
large microvilli
located inner ear, male and female genital tract

22
Q

What is the resolving power of the light microscope?

A

0.2 um

23
Q

What are some advantages and disadvantages of the LM?

A

advantages: relatively inexpensive, rapid diagnosis, allows observation of living specimen
disadvantages: image is 2-dimensional, requires maintenance, resolving power is limited by wavelength of light

24
Q

advantages and disadvantages of TEM?

A

advantages: great resolution, very useful for rapid diagnosis
disadvantages: 2-dimensional image, image is black and white, cannot use on living objects, very expensive

25
Q

What is the term used for any agent, or factor that can cause congenital anomalies in an embryo or fetus?

A

Teratogen

26
Q

What does the ectoderm makeup?

A

skin, lining of oral & nasal cavity & anus. nervous system

27
Q

What does the mesoderm makeup?

A

connective tissue, muscle, cardiovascular system…

28
Q

What does the endoderm makeup?

A

epithelial structures: lining & glands of digestive and respiratory system

29
Q

What are the 3 sections of a somite? and where is their location

A

dermatome=dermis
myotome=muscle
sclerotome=cartilage, tendons, endothelia

30
Q

What are the 2 main roles of mitochondria?

A
ATP generation
Cell Death (necroses and apoptosis)
31
Q

Which secretory vesicle requires Ubiquitin for intracellular digestion?

A

Proteasomes

32
Q

Which secretory vesicle contains the enzyme catalase?

A

Peroxisomes