Exam 1 Flashcards

1
Q

Resting potential

A

the net flow of all ions is zero (above and below the x-axis is the same)

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2
Q

Equilibrium Potential

A

for a specific ion, when its net flow is zero at a this voltage (where its line intersects the x-axis)

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3
Q

Nernst equation

A

Z, valence -
Xo - extracellular
X1 - intracellular

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4
Q

Which ion flows more at _____ .

A

whichever is closest to the x-axis, this one has more channels therefore more flow

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5
Q

If cell needs to be maintained at ____, what can do?

A

create a pump that pumps 1 Na+ out/ 4 K+ in ( for 10+, find voltage on X-axis and goes up or down to both ion lines)

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6
Q

The lipid bilayer is permeable to ____?

A

water - most permeable, using aquaporins

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7
Q

In water, ions diffuse whenever there is … ?

A

a nonzero temperature

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8
Q

Osmosis can be defined as

A

diffusion of water down its concentration gradient

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9
Q

Osmosis can be defined as

A

diffusion of water down its concentration gradient

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10
Q

When placed in distilled water the cell will…

A

expand

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11
Q

When the membrane potential is equal to the Na+ equilibrium potential, an individual ion moving through a leak channel is….

A

pushed by the electric field towards the more negative side

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12
Q

Based on our discussions, the resting potential of a cell can be defined as the membrane potential where….

A

the sum of Na+ and K+ flows through the membrane is zero

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13
Q

Diffusion of K+ ions through K+ channels requires energy…

A

never

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14
Q

The Na+/K+ pumps

A

maintain constant intra an extracellular K+ and Na+ concentrations

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15
Q

One important difference between Na+ and K+ voltage-gated channels is that….

A

K do not inactivate, Na do

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16
Q

The highest concentration of ligand-gated Na channels in a neuronal membrane is located at the …

A

postsynaptic site

17
Q

The highest concentration of voltage-gated Na channels….

A

Axonal initial segment

18
Q

During an action potential, the membrane potential changes as much as…

A

100mV

19
Q

Considering that the main ions that flow during an action potential Na and K, the peak value of the action potential is limited by…..

A

the nernst for Na

20
Q

Action potentials propagate…

A

in every direction, away from the location where they were initiated

21
Q

The basic mechanism of action potential propagation is…

A

the diffusion of Na ion along the axon

22
Q

In a myelinated neuron, APs cannot propagate if voltage-gated Na+ channels are..

A

present only at the axon hillock

23
Q

Voltage-gated Ca channels are useful for synaptic transmission at this location:

A

presynaptic site

24
Q

At synapses, Ca ion cause presynaptic vesicles to …

A

fuse with the presynaptic membrane to release neurotransmitter in the synaptic cleft

25
Q

For a chemical synapse to function properly, the NT released in the synapse…

A

must be removed from there as quickly as possible to increase the rate of synaptic transmission

26
Q

Certain NT/postsynaptic receptors combinations have a inhibitory effect on the postsynaptic neurons because…..

A

those receptors increase the excessive negative charge inside the cell

27
Q

The primary role of an inhibitory synapse is to…

A

prevent the postsynaptic neuron from firing APs in response to excitatory input from other neuron