Exam #1 Flashcards
pain
- whatever the patient experiencing the pain says it is
- pain with someone who has dementia can be experienced as aggitation
- comotose and metnally disabled pts can feel pain just the same
- pain clinics and pain teams in hospitals assigned to deal specifically with pain
why is pain undertreated?
- physicians have: inadequate knowledge in assessment, unwilling to believe pts, lack of time, may think pain management can cause death, inadequate info about addiciton
- pts might not report pain due to: fear of addiction, fear of side effects, belief that pain means they are getting worse, desire to be a “good pt”
pain mechanisms
- nociception: physiologic process by which info about tissue damage is communicated to CNS
1 transduction
2. transmission
3. perception
4. modulation - acute, unrelieved pain leads to chronic pain
- pts can develop adaptive and maladapative mechanisms for dealing with pain (behavioral, addiciton)
how does pain affect pts?
- pysiologic: prolonged stress response, increased HR, increased BP, increase o2 demand, decreased GI motility, immobility, decreased immune response, delayed healing, increased risk for chronic pain
- quality of life: interferes with ADLs, causes anxiety, depression, fear, anger, poor sleep, impairs relationships
- financially: very expensive (lost income, medications, hospitalizations)
Acute pain
- diminishes as healing occurs; responds well to analgesics
chronic pain
- lasts longer than 3 months, nerves may become oversensitive and react to even a slight stimulus
neuropathic pain
- c/b(?) damage to CNS or PNS; not well-controlled by opiods alone, needs adjuvant therapy
- shingles, diabetic neuropathy
- gabapentin, lyrica
- numbing, shooting, stabbing, sharp, electric shock like, burning
tolerance
- body adapts so that exposure to a drug causes changes that result in a decrease in one or more of the drug’s effects
physical dependence
- symptoms c/b abrupt cessation, rapid dose reduction, decreased blood level, and/or administration of an antagonist
addiction
- primary, chronic, neurobiologic disease with genetic, psychosocial and environmental factors
pain assessment
- 5th vital sign
- must assess in a mutlidimensional way
- document the specific words the patient uses
- pattern: onset, duration
- location: local, generalized, referred, radiating
- describe the site, point to the site, drawon on body map, describe every location
- intensity
- quality
- associated symptms
- management strategies
- impact
- DOCUMENT and REASSESS every 30-60 minutes
paint nursing diagnosis
- asses an ‘acceptable’ level of pain for your patient
- don’t plan to make the pain go away all together
- “decrease in pain within one hour of nursing intervention”
OLDCARD & PQRST
- onset, location, duration, characteristics, aggrivating factors, relieveing factors, treatment
- provoke, quality, radiate, severity, time
basic principles of pain treatment
1) follow the principles of pain assessment
2) evert pt deserves adequate pain management
3) base the tx plan on the pt goals (acceptable level according to pt)
4) use both drug and nondrug therapies
5) when appropriate, use a multimodal approach to analgesic thearpy
6) address pain using mutidisciplinary appraoch
7) evaluation the effectiveness of all therapies to ensure they are meeting the pt goals
8) prevent and/or manage med side effects
9) incorporate pt/caregiver teaching throughout assessment and treatment
* administer PRN pain meds “PER DR ORDER”
Drug Therapy for Pain
- non-opiods: mild pain; IBprofen, tylenol, naproxin
- opioid with tylenol: moderate pain
- opioid: moderate to severe pain; morphine; must be on a stool softener 2x day
- adjuvant: neuropathic pain and moderate pain
- treatment can be more effective using meds from more than one group - nonstepor w opiod can help with diff types of pain (bone, cancer)
- “drug ceiling”: drug no longer has an effect after a certain dose
non-opiods for pain
- NSAIDs, acetomenophen, aspirin, tylenol
- NSAIDs, acetomenphehn, aspirin
1) have analgesic ceiling
2) do not produce tolerance or dependence
3) available OTC (most) - mild to moderate pain
- used with opioids to allow for lower opioid levels “opioid sparing effect”
types of Opioids
- work by modifying pain perception
- agonists, and agonist-antagonists
- AVOID giving: darvon and demerol (produce toxic metabolite causeing seizures; DO NOT give to 65+)
- bind to receptors in the CNS and cause 1) inhibition of the transmission of nociceptive input from the periphery to the spinal cord 2) altered limbic system activity 3) activation of the descending inhibitory pathways that modulate transmission in spinal cord
- act on NOCICEPTIVE processes
Opioids for pain
- use for moderate to severe pain; breakthrough pain
- only need one b/c they are all very similar pharmacologically
- can be given by any route - prefer oral route unless pain is severe or need dose titration
- use an equianalgesic chart when changing from IV to oral (conversion chart)
codeine
- weak opioid
- requires an enzyme to break it down to work
- not good for severe pain
- use with a stool softener
hydrocodone
- opioid
- always combined with tylenol or Ibuprofen (lortab, vicodin, vicoprogen) so dose limited
Oxycodone
- opioid- single or combined
- oxycontin is long acting
morphine
- gold standard opioid
- roxanol, avinza, MS contin = long acting
- drug of choice for the elderly, can be given in small doses
hydromorphone
- opioid
- dilaudid
- 8x more potent than morphine
- only short acting
fentanyl (duragesic)
- 72 hour patch (duragesic)
- oral losange (actiq, lollypop)
- not for the opioid-naive
methadone
- opioid
- works on 2 receptors
- long hald-life (24-36 hours)
- sedation
- bad for elderly
tramadol
- ultram
- atypical opioid
- can cause seizures; avoid in pts with history of seizures
- effective in: low back pain, osteoarthritis, fibromyalgia, diabetic peripheral neuropathy,
- side effects: nausea, constipation, dizziness, sedation
opioid common side effects and treatment
- constipation - bowl regimen, stool softener
- nausea/vomiting - antiemetics, resolves with tolerance (24-48 hours)
- sedation - resoolve with tolerance 2-3 days, stop sedatives
- respiratory depression - used a sedation scale, decrease dose, narcan
- itching (pruritis) - benadryl, low dose infusion of narcan with epidural use
Less common side effects of opioids
- urinary retention
- dizziness
- confusion
- hallucinations
- opioid induced hyperalgesia (OIH) - opioids taken over time can increase sensitivity to pain
adjuvants
- can be used alone or in combination
- meds that are not typically used for pain but can be used for it in special cases
- common adjuvants: antidepressants, antisizure drugs, GABA receptoragonist, anesthetics
corticosteroids, adjuvant
- corticosteroids (prednisone, dexamethasone): best for cancer pain, spinal cord compression, inflammatory joint pain; many side effects; don’t give with NSAIDs
antidepressants, adjuvant
- antidepressants (TCAs - elavil, SNRIs - cymbalta)
- increase seratonin & norepinephrine, promotes sleep, don’t give if history of seizures or cardiac disease, bad for older adults, many side effects, SNRIs have less side effects but cost more)
- inhibit transmission of nociceptive signals in the CNS
antiseizure drugs, ajuvant
- lamictal, neurontin, lyrica
- affect peripheral nerves and CNS
- used for chronic pain
gaba receptor agonists, adjuvant
- baclofen
- inhibits pain transmission, used for muscle spasms, best used intrathecally
- spinal cord injuries, cerebral palsy
- used for muscle spasms
alpha adrenergic agonists, adjuvant
- clonidine, zanaflex
- used for chronic headaches, neuropathic pain
local anesthetics, adjuvant
- interrupes transmission of pan signals to the brain, works for types of neuropathic pain
- bupivacine, ropivacaine
pain med administration
- scheduling: focus on preventing and controlling pain, pre-medicate before painful activities, give regularly with constant pain, fast acting for breakthrogh or incident pain, sustained release for constant pain
- titration: adjusting dose based on adequacy of analgesic effect vs side effect (switching from one med to another)
- equianalgesic dosing: carefully monitor and adjust for each individual pt
oral pain meds
- route of choice if GI system is good
- opioids requires a larger dose than IV or IM due to first-pass effect
- skiwer inset, peak 1-2 hours
- dont crush, break, chew sustainted release drugs (MS contin, oxycontin)
sublingualbuccal pain meds
- bypasses the first pass effect
- doesnt always work well
- fentanyl can be given in a lollypop
intranasal pain meds
- stadol, sumatriptan
- used for headaches
rectal pain meds
- often overlooked
- good if pt has nausea and vomiting, NPO
- lasts 4-6 hours
- can’t use if a bleeding risk
transdermal pain meds
- fentanyl patch
- slow to reach affect when first applied
- can cause death from overdose (slow rr, confusion, dizziness)
- can absorb med too quickly if febrile
topical pain meds
- creams and lotions
- trolamine salicylate for joint/muscle pain; capsaicin; EMLA
- little systemic absorption, can cause skin reactions
parenteral pain meds
- SC, IM, IV
- IM not recommended due to pain, unreliable absorption, avscesses with frequent use
- SC is rarely used due to slow response, but can be used if no IV access
- IV is best for immediate analgesia and rapid titration; fastest onset but shortest duration; peaks 5-15 minutes; not good for constant pain
intraspinal pain meds
- epidural or intrathecal
- intermittent bolus or continuous
- can place tip of catheter as close to the nerve as possible
- highly potent requiring much smaller doses
- side effects are itching, nausea, urinary retention
- uses: catheter displacement, accidental infusion of neurotoxic agents, infection
- implantable pumps, intrathecal delivery by pump
Patient Controlled Analgesia (PCA)
- IV delviery system or epidural catheter
- pt decides when does is needed
- can have a continuous basal rate
- be careful with opioid naieve patients
- monitor sedation level and resp rate
- important to do good patient teaching
- give before pain is severe
- assure them they can not overdose
- only the pt can push the button
interventional therapies for pain
- nerve block: regional anesthesia, used during and after surgery, sometimes used for chronic pain syndromes
- neuroablative techniques: used for severe pain unresponsive to other tx, destorys the nerves by surgical resection or thermocoagulation
- neuroaugmentation: electrical stimulation of the brain and spinal cord, used for chronic back pain from severe nerve damage, also CRPS, spinal cord injury
non-drug pain therapies
- massage: superficial, deep, trigger point
- exercise: esp with chronic MSK pain
- TENS: transcutaneous electrical nerve stimulation, for acute pain
- acupuncture
- heat
- cold
- distraction
- hypnosis
- relaxation strategies
nursing care for pain
- effective communication
- overcome barriers to pain management
- tolerance: opioid rotation, remeber there is no uipper limit with pur opioid agonists
- dependence: taper when discontinuing
- addiction: no true risk factors, dont let it keep you from treating moderate to severe pain and chronic pain
joint commission requirements for pain
- recognize pt right to appropriate assessment and management of pain
- identify pain during initial assessment and during ongoing, periodic reassessments
- educate and ensure competency of HCPs regarding pain assessment and management
- educate patients and familites about pain management
ethical issues with pain
- fear of hastening death, no scientific evidence of this even at end of life, rule of double effect
- requests for assisted suicide, aggressive pain management could actually decrease this
- use of placebos, condemned by several professional organizations
gerontologic considerations for pain
- often inadequatly assessed and treated
- pts/HCPs often believe it is a normal, inevitable part of aging and nothign can be done
- elderly often don’t report pain, may have trouble taking about it
- they have a high prevalance of cognitive, sensory-perceptual, and motor problems that make pain harder to assess
- metabolize drugs slower, start low and go slow (tylenol)
- NSAIDs cause serious GI bleeding in elderly
- often taking many drugs for chronic problems
- cognitive impairment/ataxia can be worsened with analgesics
- very important to incorporate nondrug therapies
nonverbal pts and pain meds
- ask anyway
- look for potential causes of pain
- observe for behaviors indicating pain (grimacing, rubbing, goaning, agitation)
- try an analgesic and see if it works
substance abusers and pain meds
- still have a right to pain management
- can still use opioids but don’t use opioid agonist-antagonist
- avoid psychoactive drugs
- may need higher doses or increased frequency
- need a multidisciplinary approach
primary role of nurse in pain management
- believe the patient’s report of pain
NSAIDs, non-opioid pain
- NSAIDS: decrease production of pain-sensitizing chemicals, pts should try a variety of NSAIDs; all have COX in them; ibuprofen, naproxen, ketorolac, celecoxib;
- used for mild to moderate pain
- do not produce tolerance or dependence
- have an analgesic ceiling
- used with opiods to give locer opiod doses
- can cause GI problems, cognitive impariment, hypersensitivity
- at risk for NSAID toxicity: history of ulcer disease, older than 65, using corticosteroids or anticoagulants; more at risk for cardicascular events like MI, stroke and heart failure; patients who have just had heart surgery should not take NSAIDS
- NSAIDs: can caused bleeding, renal toxicity, CHF in elderly, some interactions with anticoagulatns, oral hypoglucemics, antihypertensive, diuretics
acetomenophen, non-opioid for pain
- acetomenophen: can cause hepatoxicity; percocet and lortab have acetomenophen in them
- Tylenol: does not cause bleeding, but can be toxic to the liver; has analgesic and antipyretic effects; no antiplatelet or antiinflammatory effects
- ceiling = 3mg
aspirin, non-opioid for pain
- ASA: use limited by side effects (bleeding, ulcers), mild pain
opioid agonists
- agonists: morphine, oxycodone, hydrocodone, codeine, methadone, hydromorphone; often combined with non-opiod analgesics limiting the total daily dose that can be given
- used for acute and chronic pain
- pure opioid agonists: morphine, oxycodone, hyrdocodone, codeine, methadone, hydromorphone
- moderate to severe pain; no ceiling
- moderate pain = opioid combined with non-opioid
opioid agonist-antagonist
- agonist-antagonist: nubain, talwin, stadol; produce less resp depression but causes more dysphoria and agitation, have analgesic ceiling, can lead to withdrawl, not used much
- work on kappa (agonists) and mu (antagonist) receptors
- less resp depresion than pure agonists
- more dysphoria and agitation
substance abuse
- in the last 12 months, have had one or more of the following:
1) failure to fullfill major role obligations (school, work, home)
2) recurrent use even when it is hazardous (driving, operating machinery)
3) recurrent substance related legal problems
4) continued use despite relationship problems
addiction
- primary, chronic, neurobiologic disease with genetic, psychosocial, and environmental factors:
1) loss of control over use
2) continued use despite knowledge of harmful consequences
3) compulsion to use
4) craving “surviving to get fix”
dependence
- reliance on a substance that has reached the level that absence of it will cause an impairement in function
- in the last 12 months, have had 3 or more of the following:
1) tolerance
2) withdrawl
3) taking in large amounts or for longer than intended
4) uable to control use
5) great deal of time spent getting the substance, using the substance or recovering from the substance
6) important social/recreational activities are given up because of the substance
7) continued use even with known health or psychological problems caused by substance
common health related problems related to substance abuse/dependence
- COPD - smoking
- Cancers - smoking, drinking
- heart disease
- peptic ulcer disease
- GERD
- chronic sinusitis - cocaine
- uncontrollable tremors
- respiratory depression
- memory impairment
- skin infections - heroin, meth, absesses
- blood clots
- hepatitis B & C - IVs
- HIV/ADIS
- malnutrition
Nicotine
- most common addictive behavior
- smoking is the most harmful method
- injures nearly every organ in the body: lung disease, CV disease, cancer, cataracts, pneumonia, periodontitis, aortic aneurysms, menstrual problems, infertility, delayed wound healing
- damage from chronic respiratory irritation, carbon monoxide (decreased oxygen carrying capacity of the blood)
tobacco cessation products
- every healthcare provider is required to address this with patients
- nicotine replacement products to reduce craving and withdrawl (with patient in hospital)
- chantix: gives some nicotine effects but also blocks the effects of nicotine if they resume smoking (vivid dreams, suicidal thoughts)
- zyban: atnidepressant, reduces the urge to smoke. reduces some withdrawl symptoms, prevents weight gain
- tobacco cessation programs should be used with nicotein replacement programs
tobacco cessation 5As and 5Rs
- 5 As:
1. ask - identify all tobacco users at every contact
2. advise - strongly urge all tobacco used to quit
3. assess - determine willingness to quit
4. assist - aid the pt in developing a plan to quit
5. arrange - schedule follow-up contact - 5 Rs:
1. relevance - ask the pt to tell you why quitting is personally relevant
2. risks - ask the pt to identify consequences of tobacco use
3. rewards - ask the patient to idetify potential benefits of stopping tobacco use
4. roadblocks - ask patient to identify barriers to quitting
5. repetition - repeat process every clinic visit
Benefits of smoking cessation
- in 20 minutes: BP decreases, HR decreases, body temp and hangs/feet increase
- in 12 hours: carbon monoxide levels in blood drops to normal, oxygen level increases to normal
- in 24 hours: chance of heart attack decreases
- in 48 hours: nerve endings start regrowing, ability to smell and taste is enhanced
- in 2 weeks to 3 months: circulation improves, walking becomes easier, lung function increases, coughing/sinus congestion/fatigue/SOB decrease
- in 1 year: risk of heart disease decreases to half that of a smoker
- 10-15 years: risk of stroke, lung and other cancers, and early death returns to nearly the level of people who have never smoked
Stimulants
- work by increasing the amount of dopamine in the brain producing euphoria, alertness, and raid dependence
- Nicotine, cocaine, amphetamines, methamphetamine, ritalin, caffeine
- overdose is common, death does occur
stimulants overdose
- overdose: restlessness, paranoia, agitated deliruym, confusion, reptetive behaviours, seizures, combative, fever, high HR/BP
- no antidote for cocaine or amphetamines
- patent airway, IV access, 12-lead ECG, treat dysrhythmias, treat HTN, tachy, give ASA to prevent MI, give valium or ativan for seizures, avoide resptraints
- withdrawl: few physical symptoms but intense cravings, may become depressed
depressants
- alcohol, sedatives, hypnotics, opioids
- sedative-hypnotics: barbituates, benzodiazepines, barbituate-like drugs; depress CNS at low doses and sleep at high doses; high doses can give initial euphoria
- opioids: illegal or legal; cause CNS depression and major effect on the brain regawrd system; usually injected IV so increased risk of disease
depressant overdose
- causes death from resp depression/arrest, nausea and vom, slurred speech, confusion, drowsiness, low HR, low BP, low RR
- need serum and urine drug screens
- ABCs is priority
- ensure pt airway, IV access, 12 lead EKG, drug levels, give antidotes, gastric lavage, activated charcoal
- need to see a psyhiatric professional before being released
- sedative hypnotics: antidote for benzodiazepines is flumazenil (romazicon) - can cause seizures in people with physical dependence; charcoal can be given within 4-6 hours
- opioids: antidote is naloxone (narcan), does may have to be repeated
depressant withdrawl
- most dangerous and should be observed for in any patient with a history of substance abuse (including alcohol)
- sedative-hypnotics: severe symptoms can start within 24 hours, persist for 3-5 days, with mild symptoms persisting for 2-3 weeks
- signs and symptoms: craving, delirium, seizures, resp/card arrest
- tx: long acting meds (valium, klonopin) gradually taper after stabalization
- opioids: happens when drug is decreased or stopped or naloxone is given
- s/s: craving, abdominal cramps, diarrhea, n/v, sweating
- tx: symptom-based and doesn’t always require medications
- uncomfortable but isn’t life threatening
- methadone in decreasing doses can decrease symptoms
methadone
- PO opioid
- blocks the “high” caused by using opiates (doesnt cause euphoria or intoxication)
- produces stable levels of the drug in the brain so the patients odesnt get a rush
- helps decrease the patient’s desire to use opioids (reduces cravings, prevents withdrawl)
- do not use with alcohol
- sometimes used to treat chronic pain
- usually taken in a supervised setting
alcohol
- alcohol dependence usually occurs over a period of years
- chronic, progressive, potentially fatal disease
- affects almost all cells of the body, but particularly CNS (depressant)
- women have higher blood alcohol levels than men with the same amount
- Blood alcohol concentration BAC:
- 0.02 - one drink, light drinkers will feel it
- 0.06 - judgement is mildly impaired
- 0.08 - judgement is clearly imparied, legal intoxication in some states
- 0.1 - legally intoxicated in most states
- 0.3 - usu lose consciousness
- 0.45 - stop breathing
health problems with alcohol
- alcohol dimentia
- wernicke’s encephalopathy (increased amonia levels)
- depression
- ADD
- seizures
- peripheral neuropathy
- decreased immune system
- increased cancer risk (GI)
- anemia
- osteoporosis
- liver disease
- testicular atrophy
- spider angiomas (spider veins of face, red butterfly effect on face)
alcohol intoxication
- occurs after binge drinking or using alcohol with CNS depressants causing resp and ciruclatory failure
- maintain ABCs until detox is complete and alcohol is metabolized
- closely monitor VS and LOC
- no antidote for alcohol, should not give stimulants or depressnts
- administer IV thiamine first and then IV glucose = banana bag
- watch for hypoglycemia, low magnesium levels
- expect agitaiton and anxiety
- risk for injury, agitation
- continue assessment and intervention until BAC is 0.1
alcohol withdrawl syndrome
- tell pts to be honest about how much they use to help with withdrawls
- delirium tremens
- if you are non-dependent, you have a hangover
- if dependent and hospitalized, can develop alcohol withdrawl syndrome:
> occurs 4-6 hours after last drink and contunues 3-5 days
> minor: anxiety, increased HR, increased BP, sweating, nausea, hyperreflexia, insomnia
> major: visual/auditory hallucinations, tremors, seizures, delirium
> alcohol withdrawl delirium: disorientation, visual/auditory hallucinations, hyperreactivity, death from hyperthermia, peripheral vascular collapse, cardiac failure - prevent this by giving benzodiazepine (ativan), tegretold or dilantin to prevent seizures, antipsychotics (haldol, throazine) if benzodiazepines dont work
- quiet calm environment, don’t restrain