Exam 1 Flashcards

0
Q

Turbid urine may be due to

A
crystal precipitaion
bacteria, yeast
WBC, RBC
Mucus, squamous epithilial cells (normal)
Sperm, prostatic fluid, lipids
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1
Q

Urine appearance: Color
Normal: pale straw colored or dark amber
Abnormal

A

Red or red brown - blood or hemoglobinuria
R/O menstrual contamination, food dyes, myoglobin beets.

Dark brown to black - BILE OR BILIRUBIN, melanoma

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2
Q

fruity odor is a sign of

Abnormal odors are due to

A

Ketone bodies/DM

UTI, cigarrettes, AA disorders

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3
Q

Urine Dipstick checks for

A

pH, Spec gravity, glucose, ketones (fruity), protein (turbid smell), blood (red), Nitrite and Leukocyte estrase = UTI, Bilirubin and Urobilinogen = liver dz

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4
Q
  1. Normal pH is

2. pH > 8 is a sign of

A
  1. 4.5-8.0

2. of urine sitting too long and bacterial overgrowth (contaminated due to long processing time)

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5
Q

Specific Gravity of H2O is 1, everything else is substance wgt
Normal SG si

A

1.003 - 1.035

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6
Q
  1. SG reflects the ability of kidneys to

2. With kidney dz, the SG is fixed at

A

concentrate the urine

1.010 (same as filtrate due to inability to concentrate urine)

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7
Q

When renal threshhold of glucose >150 is exceeded, the glucose is spilled into urine.
In some types of kidney defects, the renal threshold for glucose is

A

lower

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8
Q

Urine Glucose False Negative can be due to

A

Vit C

Aspirin

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9
Q

Ketones are a result of low carb diet (rapid wgt loss, starvation, DKA diabetic ketoacidosis, pregs)
Presence of ketones in urine represents

A

Acidosis

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10
Q

Normal protein in urine is < 150
30% albumin
30% globulin
40% Tamm-Horsfall protein (A mucoprotein secreted ONLY by renal tubular cells)

A

High SG - may give higher protein level

lower SG - may give lower protein level

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11
Q

Tomm Horsfall protein is

A

a mucoprotein that is secreted ONLY by renal tubular cells

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12
Q

Falsely positive for protein if

A

High alkaline urine
Hematuria (blood picked up as protein)
Pyridium present (analgesic for UTIs in addn to ABs)
High SG

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13
Q

Microalbuminuria

A

excretion of albumin BELOW dection level of 300, but ABOVE normal:
EARLY sign of diabetic neuropathy
urine dipstick doesn’t detect < 300
other causes: excercise, fever, cystitis (UTI) and CHF

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14
Q

Glomerulonephritis (and vasculitis) has was type of casts

A

Red cell casts

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15
Q

Acute pyelonephritis has which casts

A

White cell casts
(infection, fever, low back pain + White casts)
kidney inf not bladder

16
Q

Granular cells are

A

from renal tubular cell casts (injury to epithilium)
old epithilium sloughing off
rectangular shape

17
Q

Distended tubules, kidney dz

A

waxy casts:

broad, sharp edges with crackles

18
Q

Urine culture is most relaible to dx infections

range indicative of inf is

A

> 100,000 colonies

19
Q

hyaline casts are

and made of

A

very pale and made of Tamm-Horsefall mucoprotein secreted by tubule cells only

20
Q

High number of epithilial cells in UA is a sign of

A

contamination

21
Q

oval cell bodies consist of

A

degenerated tubular cells that contain high amounts of lipid,
maltese cross on microscope

22
Q

Large amount of renal tubular and transit epithilial cell are a sign of

A

tubular degeneration

23
Q

Normal WBC in urine is

A

0-5
10-20 suspect UTI
>20 = UTI

24
Q

If sediment is red after centerfuging

A

Its hematuria

25
Q

If supernatent (top part) is RED after centerfuging

A

Do a dipstick for HEME,
If HEME is neg - it’s beets
if HEME is pos - its either Myoglobin (clear plasma) or Hemoglobin (red plasma)

26
Q

Abnormal range for RBCs in urine

A

> 3

27
Q

Causes of RBCs in urine

A
kidney stones, renal and urinary tract trauma
glomerular damage
tumors
UTI
menstrual contamination
28
Q

Bilirubin and Urobilinogen in urine is a sign of

A

LIVER dz

29
Q

Proteinuria is a sign of

A

KIDNEY dz
due to endothelial dysfx
(in blood vessels, endothelial dyxfx results in atherosclerosis)

30
Q

Tx of proteinuria

A

Decrease BP
ACE inhibitor
Low protein diet

31
Q

Microalbuminuria is a

A

early sign of diabetic neuropathy
other: excercise, fever, cystitis (UTI), CHF

use 24 hr urine or alb to creat ration (first am void)
<30 is normal