Exam 1 Flashcards
What is osteology?
the study of bone
What are the four tissues of the human body?
epithelial, muscle, neural, & connective tissues
What are the three primary cell types of bone?
osteoblasts, osteocytes, and osteoclasts
What is the function of each type of bone cell?
osteoblast–to form bone
osteocyte–maintain or nurture bone
osteoclast–remodel bone
What are the bone cells embedded in?
an amorphous matrix consisting of ground substance, protein fibers and various minerals
What is the primary constituent of the ground substance?
glycosaminoglycans
What types of glycosaminoglycans predominate in bone?
chondroitin sulfates, keratin sulfates, and hyaluronic acid
What is the principal type of protein fiber in bone?
collagen type 1
What is the primary constituents of the bone mineral?
calcium, phosphate, citrate, and carbonate ions
What is the most frequently described deposit in bone?
hydroxyapatite
Bone is also the repository for what additional ions?
sodium, magnesium, flouride, lead, strontium, & radium
What is Wolff’s Law as it pertains to bone?
living tissue will respond to stressors; bone is formed or absorbed in response to stress
What are the three responses of bone which allow it to be described as “living”?
it has the ability to heal, to remodel under stressors, and to age
What is bone the embryological derivative of?
mesenchyme or cartilage
What is the name given to the pattern of ossification in mesenchyme?
intramembranous ossification
What is the timing for the appearance of intramembranous ossification?
from the second to third month in utero