Exam 1 Flashcards
When did embalming start?
Ancient times
When did the preservation of foods using microbiology start?
Ancient times
Who is the English scientist famous for his work with microscopes?
Robert Hooke
When did Robert Hooke study his cells of cork?
1600 to 1800
Who coined the word cell?
Robert Hooke
What is Anthony van Leeuwenhoek famous for?
Primitive microscope using ground glass
What nationality is Anthony van Leewenhoek?
Dutch
Who is famous for identifying “animalcules”?
Anthony van Leeuwenhoek
Who opens up the science of microbiology?
Anthony van Leeuwenhoek
What is Francesco Redi famous for?
Beginning to disprove spontaneous generation
What nationality is Francesco Redi?
Italian
Who set up jars of meat to test spontaneous generation theory?
Francesco Redi
What is Edward Jenner famous for?
First vaccine against small pox using cowpox scraping.
What is profession of Edward Jenner?
Medical doctor
When was Anthony van Leeuwenhoek’s work?
1600 to 1800
When was Francesco redi’s work?
1600 to 1800
When was Edward jenner’s work?
1600 to 1800
When was Louis Pasteur’s work?
1800
What is Louis Pasteur famous for?
Pasteurization
What two industries did Louis Pasteur save in France?
Wine Silkworm (silk industry)
What vaccine did Louis Pasteur develop?
Rabies
Who is famous for the germ theory?
Robert Koch
When is Robert koch’s work?
1800s
When was Louis Pasteur’s work?
1800
What did people use to think about germs in 1800s?
If you were immoral or bad you would get diseases.
What is step one of Koch postulates?
Disease and microbe must Always be present in host.
What is step two of Koch postulates?
Isolate microbe in pure culture
What is step three of Koch postulates?
Infect new healthy host with microbe from pure culture and produce disease again.
What is step four of Koch postulates?
Reisolate microbe from second host
What are three problems with Koch postulates?
Viruses:step two cannot be carried out because they need a host
Small Pox:only in humans, who would want to participate?
HIV:symptoms take decades to show up
What solidifying agent did Robert Koch start using?
Agar
What did Robert Koch establish?
Pure cultures using agar
Who was the doctor who first started sterilizing surgical instruments?
Joseph Lister, MD
Who suggested hand washing in healthcare?
Ignaz Semmelweis
When was hand washing in healthcare suggested?
1800s
When were surgical instruments first sterilized?
1800s
When was Salvarsan (first chemical for disease) discovered?
1900s
How many chemicals did Paul Ehrlich study?
606
What does Salvarsan kill?
Syphlis
What is the base of Salvarsan?
Arsenic
What did Paul Ehrlich discover?
Salvarsan and sulfa drugs still used today
Who discovered Salvarsan? When?
Paul Ehrlich, 1900s
Who discovered the first true antibiotic?
Alexander Fleming
What did Alexander Fleming discover?
1st antibiotic, penicillin
Antibiotic definition?
Chemical produced by one organism to prohibit the growth of another organism
When did the mass production of penicillin begin?
1940s, WWII
When did the age of antibiotics begin?
1950s
Who discovered the structure of DNA?
Watson and Crick
When was the structure of DNA discovered?
1953
When were restriction enzymes discovered?
1970s
What was the result of the discovery of restriction enzymes?
DNA could be manipulated
When was polymerase method for copying DNA discovered?
1980s
What could be used to diagnose viral infections?
PCR, polymerase method
Now how do viral infections get diagnosed?
Wait for body to produce antibodies
When was the Nobel prize awarded for the discovery of prions?
1997
When was the human genome project?
2000
What was the human genome project?
Discovered the order genes come in, ATCG
When was the anthrax scare?
Right after 9/11, 2001
When was SARS and bird flu discovered?
2003
What is mortality rate of bird flu?
50%
When did government and world begin to prepare for bird flu and growing awareness begins?
2005
When was the swine flu H1N1 scare?
2009
What are the three shapes of bacteria?
Coccus
Bacillus
Sprillum
What is strepto?
Chain of bacteria
What is tetrad?
4 cluster bacteria
What is sarcinae?
8 cluster bacteria
Bacillus, plural or singular?
Singular
Bacilli, plural or singular?
Plural
Bacterium, singular or plural?
Singular
Bacteria, singular or plural?
Plural
What is vibrio?
Rice like shape of sprillum bacteria
What are agents?
Non-living and infectious
Can viruses replicate on their own?
No
What are germs and pathogens?
Disease causing microbes
What % of atmosphere is nitrogen gas?
79%
What are building blocks of
Protein?
Amino acids
What is microbiology definition?
Study of little life forms
Are microbes living?
Yes
Where are 7 places you expect to see normal flora?
Nose/throat Eyes Mouth Skin Large intestine Vagina Urethra
What is nitrogen fixing?
Microbes that take nitrogen and make new amino acids
What are the 3 domains of organisms?
Eubacteria
Archaea
Eukarya
What is binary fission?
Split in two!
Bacteria belong to what domain?
Prokaryotic
What does prokaryotic mean?
No organelles, simple cells
What is in bacteria cell wall?
Peptidoglycan
Bacteria are unicellular, t or f?
T
Viruses are acellular, t or f?
T
What is the protein coat on viruses called?
Capsid
Are viruses parasitic?
Yes, always!!
What domain are fungi in?
Eukaryotic
What domain are protists in?
Eukaryotic
Protists are unicellular, t or f?
T
How are protists classified?
By means of movement
What are helminths?
Multicellular worms
What are prions?
Infectious proteins
What is the body’s response to pathogens?
Immune system
What is mycology?
Study of fungi
What is parasitology?
Study of worms and protists
What does molecular biology study?
RNA and DNA
What belongs to eukarya classification?
Plants, animals, fungi, protistans
Why do we classify?
So we can predict and not have to start over
What is eubacteria?
True bacteria, includes pathogens
Archaeabacteria do what?
Live in extreme environments, deep in ocean/bpiling water/ice
What to eukarya have?
True nuclei, complex and have organelles
2 parts of scientific name
Genus and specific epithet
Scientific name is what if written?
Underlined
Scientific name is what if typed?
Italics
How do you write scientific names in papers?
Write it out first and then abbreviate genus name and write out specific epithet
How do giardi lambia move?
Flagella
What does giardi lamblia cause?
Hikers diarrhea
Do fungi do photosynthesis?
No!
What are protists?
Eukaryotic, multi-cellular
How do protists move?
Cilia
Flagella
Psuedopodia
Is there genetic info in prions?
No
How are prions transmitted?
Through ingestion and cause neurological changes
What is humoral immunity?
Antibodies made by B cells
What shape are proteins made by humoral immunity?
Y shaped proteins that have sticky ends and have affinity for specific things
What is cellular immunity?
T cells do surveillance and kill virus infected cells and cancer cells
Are prions stable?
Yes, tremendously stable so there is no way to kill them
Dr Bruce Ivans caused what?
Anthrax scare