Exam 1 Flashcards
ANS and Gastro
What is the function of the ANS?
controls involuntary bodily functions (heart rate, digestion, respiratory rate, glandular activity)
What are the key components of the ANS?
ganglia, pre-ganglionic neurons, post-ganglionic neurons
What neurotransmitter is released by pre-ganglionic neurons in the ANS?
ACh
What neurotransmitter is released by sympathetic post-ganglionic neurons?
NE (NA), except in sweat glands (ACh)
What is the primary function of parasympathetic nervous system activation?
rest and digest - decreased HR, promotes digestion, constricts pupils
What are adrenergic receptors, and what do they respond to?
receptors for NE (NA) and E, including alpha-1, alpha-2, beta-1, beta-2
How does sympathetic activation affect the heart?
increases HR (tachycardia) and contractility
What is the effect of parasympathetic activation on the heart?
slows HR (bradycardia) and reduces conduction speed
What is the role of the LES?
controls food entry into the stomach and prevents acid reflux
What is the cause and symptom of Horner’s Syndrome?
sympathetic nerve damage to the eye causing miosis, ptosis, and anhidrosis (no sweating)
What is Myasthenia Gravis?
autoimmune disorder blocking ACh receptors at the neuromuscular junction, causing ptosis, diplopia, and muscle weakness
How does parasympathetic activation control the eye?
contracts the circular muscle, causing miosis (pupil constriction) and focuses the lens for near vision
What is the role of the accessory digestive organs?
aid in digestion but do not move food (e.g., teeth, tongue, salivary glands, liver, gallbladder, pancreas)
What is the alimentary canal and its function?
a continuous tube from mouth to anus responsible for digestion, absorption, and excretion of food
What is the function of the ENS?
regulates digestion through the myenteric and submucosal plexuses, controlling motility and secretion
What are the main digestive processes?
ingestion, propulsion, digestion (mechanical chemical), absorption, and excretion
What is GERD and its main symptoms?
gastroesophageal reflux disease caused by LES dysfunction, leading to heartburn, chest pain, and acid regurgitation
What is the function of the LES?
prevents acid reflux by regulating food entry into the stomach
What are the major layers of the alimentary canal?
mucosa (absorption/secretion), submucosa (blood vessels/nerves), muscularis (food movement), serosa (protective outer layer)
What is the function of saliva in digestion?
lubricates food, initiates carbohydrate digestion (via amylase), and protects the oral cavity
What is the function of hydrochloric acid (HCl) in the stomach?
Activates enzymes (e.g., pepsin) to break down proteins and protect the stomach lining.
What is Pepsin and its role?
An enzyme that breaks down proteins into smaller peptides in the stomach.
What is Achalasia?
A condition where the LES fails to relax properly, leading to difficulty swallowing (dysphagia) and regurgitation.
What is the role of bile in digestion?
Bile, produced by the liver and stored in the gallbladder, aids in fat digestion by emulsifying fats.