Exam 1 Flashcards
What does the specificity of a test measure?
A) The proportion of true positives among all people tested
B) The ability of a test to correctly identify those with the disease
C) The ability of a test to correctly identify those without the disease (true negatives)
D) The proportion of false positives among all people who test negative
C
What is the definition of sensitivity in a diagnostic test?
A) The proportion of true positives among all people who test positive
B) The ability of a test to correctly identify those with the disease (true positives)
C) The proportion of false negatives among all people tested
D) The ability of a test to correctly identify those without the disease (true negatives)
B
What does the Negative Predictive Value (NPV) of a test indicate?
A) The proportion of true negatives among all people with a positive test result
B) The proportion of true negatives among all people with a negative test result
C) The proportion of false negatives among all people tested
D) The proportion of true positives among all people tested
B
What does the Positive Predictive Value (PPV) of a test represent?
A) The proportion of true positives among all people with a negative test result
B) The proportion of true negatives among all people tested
C) The proportion of false positives among all people with a positive test result
D) The proportion of true positives among all people with a positive test result
D
What does external validity refer to in research?
A) The consistency of a test or measurement over time
B) The degree to which the results of a study can be generalized to other settings, populations, or times
C) The accuracy with which a test measures what it is intended to measure
D) The consistency of results across different researchers or raters
B
What does reliability mean in the context of research measurements?
A) The ability of a test to produce the same results under consistent conditions
B) The degree to which a test measures what it claims to measure
C) The extent to which a study’s findings can be generalized to other contexts
D) The precision of a study’s findings when compared to similar studies
B
What does test-retest reliability assess?
A) The agreement between different researchers’ or raters’ scores
B) The extent to which a test produces similar results when administered at different times
C) The degree to which items on a test measure the same construct
D) The generalizability of the results to other populations
B
What does test-retest reliability assess?
A) The agreement between different researchers’ or raters’ scores
B) The extent to which a test produces similar results when administered at different times
C) The degree to which items on a test measure the same construct
D) The generalizability of the results to other populations
B
Internal consistency refers to:
A) The similarity of results produced by the same test administered multiple times
B) The consistency of results across items within a single test
C) The agreement between different researchers’ scores on the same test
D) The extent to which a test correlates with an external criterion
B
Question: What does interrater reliability measure?
A) The stability of a test over time
B) The correlation between test scores and an external standard
C) The consistency of scores assigned by different raters or observers
D) The generalizability of findings across different populations
C
Question: What is criterion validity?
A) The correlation between how well a screening tool or assessment technique predicts the outcome of another measure
B) The consistency of test results across time
C) The degree to which test items measure the same construct
D) The ability of a test to be generalized to other settings
A
What does construct validity refer to?
A) The concept of testing the screening tool or assessment technique against similar measures to determine whether an association exists between measures
B) The ability of a test to produce consistent results across time
C) The correlation between test scores and an external benchmark
D) The degree to which a test accurately reflects all aspects of the construct
A
What does content validity assess?
A) The extent to which test results can be replicated
B) The consistency of scores across multiple test administrations
C) The degree to which the screening tool adequately covers the entire domain or all facets of the content it is seeking to evaluate
D) The agreement between raters on the same test
C
What does the likelihood ratio (LR) of a diagnostic test indicate?
A) The probability that a person without the disease will test negative
B) The comparison of how likely the screening test is to detect the condition (true positive) compared with how likely the test is to be accurate when an individual does not have the condition (true negative)
C) How much a test result will change the odds of having a disease
D) The proportion of true negatives among all people with a negative test result
B
What does a USPSTF Grade A recommendation signify?
A) The service is not recommended and may cause harm
B) The service is strongly recommended because the benefits substantially outweigh the harms
C) The evidence is insufficient to assess the balance of benefits and harms
D) The service should only be offered or provided to selected patients based on individual circumstances
B
What is the meaning of a Grade B recommendation from the USPSTF?
A) The service is recommended with high certainty that the net benefit is moderate to substantial
B) There is insufficient evidence to assess the net benefit of the service
C) The service should be discouraged due to moderate or high certainty of no net benefit
D) The service is strongly recommended and is proven to have substantial net benefits
A
A Grade C recommendation from the USPSTF implies which of the following?
A) The service is not recommended for the general population
B) The service should not be used under any circumstances
C) The service may be considered for individual patients based on professional judgment and patient preferences with small benefit
D) The service is strongly recommended for everyone
C
If a preventive service receives a Grade D recommendation from the USPSTF, it means that:
A) The service is recommended for all patients
B) The service has uncertain benefits and harms
C) The service is recommended to avoid due to a lack of net benefit or potential harm
D) The service should be used selectively, depending on patient risk factors
C
What does a USPSTF Grade I statement indicate?
A) The service is recommended, but the benefits are small
B) The service is not recommended at all
C) There is insufficient evidence to assess the balance of benefits and harms of the service
D) The service has moderate benefits and should be selectively offered
C
What is the term for an individual who manifests a disorder?
Affected
What is the term for one version of a gene at a given location along a chromosome?
Allele
What is the term for relation in descent by a common ancestor?
Consanguinity
What is the term for a new spontaneous mutation (non-inherited), alteration in a gene resulting from a germ cell mutation present for the first time in the family member?
De novo mutations
What is the term for the range of clinical features observed in individuals with a particular disorder?
Expressivity or variable
What is the term for the functional and physical unit of heredity passed from parent to offspring?
Genes
What is the term for the study of heredity, the process in which a parent passes certain genes onto their children.
Genetics
What is the term for all the DNA contained in an organism or a cell, which includes both the chromosomes within the nucleus and the DNA in mitochondria?
Genome