exam 1 Flashcards
What is the purpose of connective tissue?
forms metabolic and structural connections
what are the four major classes of CT?
- CT proper
- cartilage
- osseus (bone)
- blood
what makes connective tissue?
- ECM
- vascularity
- make structural elements (ground substance, extracellular fibers, cells)
what is the ECM?
the substance found between cells that provides support and nourishment
the extracellular matrix is the mixture of _____ and _____.
extracellular fibers; ground substance
what are the three types of extracellular fibers?
collagen, elastic, and reticular fibers
what is the function of extracellular fibers?
provides support and structure to the connective tissue
extracellular fibers are the ______ component of ECM.
fibrous
ground substance is the ______ component of ECM.
jelly-like or liquid
what are the three types of extracellular fibers?
collagen, elastic, and reticular fibers
collagen fibers - structure
strong, thick strands composed of collagen organized in long parallel fibers
collagen fibers - function
provide tensile strength for resistance against pulling forces
where are collagen fibers found?
tendons and ligaments
what is the structure of elastic fibers?
branched, complex fibers of elastin in coiled bundles
what is the function of elastic fibers?
they can stretch and contract without losing integrity
where are elastic fibers found?
vocal cords, lungs, skin, and blood vessels
what is the structure of reticular fibers? what is it composed of?
net-like; thin, delicate branched fibers composed of collagen and coated in glycoprotein
what is the function of reticular fibers?
they provide support around complex organs
where are reticular fibers found?
endocrine glands, liver, nerves, muscle fibers, capillaries
what are the three structural elements of connective tissue?
ground substance, extracellular fibers, and different types of cells
what are connective tissue cells?
fundamental cell types at various stages of growth
what is a fibroblast?
a non-specified, general type of cell that builds connective tissue
what is a chondrablast?
the cell responsible for building cartilage
what is an osteoblast?
the cell type responsible for building bone
what are mezenchymal stem cells?
non-specified stem cells that can become any other cell type
what is a hematopoietic stem cell?
immature cell type
what are adipocytes?
fat cells
what response are mast cells responsible for?
inflammatory
what are the properties of CT?
- cell “poor”
- ECM “rich”
- vascular
- most are dense/rigid in structure (some are fluid and flexible though)
- all derived from mezenchymal stem cells
what is the overall function of CT?
to connect, protect, and support
what are the four major classes of CT?
- CT proper
- cartilage
- bone
- blood
what are the two types of CT proper?
- loose
- dense
what is the function of loose CT proper?
to support the structure it surrounds; joins together the cells of the other main tissue types and joins tissues into organs
what is the most widely distributed CT type?
loose CT proper
what are the three subclasses of loose CT?
areolar, adipose, and reticular
what is the structure of areolar CT?
most plentiful, loosely organized, liquid, and very dense
what is the function of areolar CT?
wraps and cushions organs
what fiber types are found in areolar CT?
elastic, collagen, and reticular
what cell types are found in areolar CT?
fibroblasts, WBC, mast cells, and macrophages
where is areolar CT found?
across the body
what is the structure of adipose CT?
fat tissue; large, bubble-like, small amount of matrix
what is the function of adipose tissue?
contains reserve food stores, insulates, supports, protects, and stores energy
what fiber types are found in adipose CT?
elastic, collagen, reticular
what cell types are found in adipose CT?
adipocytes
where is adipose CT found in the body?
under skin, around kidneys, within abdomen, in breast tissue, surrounding joints, on surface of heart, behind eyes
what is the structure of reticular CT?
net-like fiber network/framework
what is the function of reticular loose CT?
form structural support for complex structures
what fiber types are found in reticular loose CT?
only reticular
what cell types are found in reticular loose CT?
fibroblasts, WBC, mast cells, and macrophages
where is reticular loose CT found?
spleen, liver, lymph nodes, blood vessels, bone marrow
what is the structure of dense CT?
highly fibrous, little vascularity, very dense
what is the function of dense CT?
to reinforce and bind body structures
what are the three types of dense CT?
regular, irregular, and elastic
what is the structure of regular dense CT?
minimally vascular, fibers lie in direction of force
what is the function of regular dense CT?
improves tensile strength
what fiber types are found in regular dense CT and how are they arranged?
tightly bound collagen fibers with few elastic fibers
what is the major cell type found in regular dense CT?
fibroblasts
where is regular dense CT found in the body?
facia, tendons, and ligaments
what surrounds soft tissue organs?
irregular dense CT
what is the function of irregular dense CT?
allows for withstanding force from multiple directions
what are the fiber types found in irregular dense CT and how are they arranged?
dense collagen fibers arranged in a sheet of
where is irregular dense CT found in the body?
dermis of skin; forms joint capsule; cover kidneys, testes, liver, and spleen
what is the function of elastic dense CT?
allows for recoil of tissue
what fiber types are found in elastic dense CT and how are they arranged?
elastic fibers arranged in a parallel or interwoven pattern with few collagen fibers
where is elastic dense CT found in the body?
space between vertebrae, artery walls, stomach, heart, and bladder
what is the function of tendons?
connects muscle to bone and enhances movement; assists muscle groups in locomotion
what are the properties of tendons?
type 1 collagen (85%), elastin (small amount), proteoglycans, aggrecan, glycoaminoglycans, inorganic molecules (Cu, Ca, Mg), and tenocytes (aka fibrocytes)
what is the function of ligaments?
connects bone to bone, stabilizes/limits movement, force resistance, “shrink-wrap” around movable joints (connects bones together without letting them go willy-nilly)
what are the properties of ligaments?
- similar to tendons
- parallel collagen fibrils
- fibroccytes - ECM components
what is the function of cartilage?
protection
what are the three subclasses of cartilage?
hyaline, fibrocartilage, elastic
what fiber types are found in hyaline cartilage and how are they arranged?
closely packed collagen fibers
what is the function of hyaline cartilage?
helps ease movements; takes grinding force off bones; gives bones some lubrication and cushion
where is hyaline cartilage found?
articular( making physical contact); at the end of long bones; found where two bones meet to prevent grinding
what fiber types are found in elastic cartilage?
elastic and collagen fibers
what is the function of elastic cartilage?
maintains shape while allowing for flexibility
where is elastic cartilage found?
epiglottis and ears
what fiber types are found in fibrocartilage and how are they arranged?
thick bundles of collagen fibers
what is the function of fibrocartilage?
cushion for joints, takes compression; helps with longevity of breeding stock
where is fibrocartilage found?
knee, pelvis and between vertebrae
what are the two sub classes of bone/ osseus tissue?
compact and spongy
what are the properties of bone/osseus tissue?
combination of collagen fibers (allow for a little bit of flexibility) and calcium salts; very vascular
what are the functions of bone/osseus tissue?
structure and protection
what is the most atypical CT?
blood
why is blood listed as a CT?
- derived from mezenchymal stem cells
- has blood cells
- surrounded by a fluid matrix (plasma)
- vascular
- connects, protects, and supports the body
What is a tissue membrane?
Thin protective layers that line the body cavity, separate organs, and cover surfaces; collaboration of ET and CT
what is the lumen?
the interior cavity of na organ or vessel
what are the four types of tissue membranes?
mucous, serous, cutaneous, synovial
what is the function of a mucous tissue membrane?
line organs with a connection to the outside environment
what is the function of a serous tissue membrane?
line closed body cavities
what is the function of a cutaneous tissue membrane?
protects an organ perpetually exposed to the outside environment
what is the function of a synovial tissue membrane?
protects joints; produces synovial fluid
what are goblet cells made of?
water, electrolytes, mucin
what are goblet cells typically associated with?
tissue membranes
what is the function of goblet cells?
decreases friction
is nervous tissue vascular or avascular?
avascular
what are the three types of muscle tissue?
skeletal, cardiac, and smooth
what are some characteristics of keratinized epithelia?
- highly regenerative
- waterproof
- help animal regulate temp and retain moisture
where is keratinized epithelia located?
skin, hair, horns, hooves
what is the process of keratinization?
as cells move from basal to apical layers, cells let go of cytoplasm and bring in granules of keratin which then dry out and flake off
what are the two major ways we classify glands?
endocrine and exocrine
what are some characteristics of endocrine glands?
ductless, produces hormones, released directly into extracellular space
what are some examples of endocrine glands?
pituitary gland, thyroid, adrenal, ovary, testes
what are the eight necessary life functions?
- maintaining balance
- movement
- responsiveness
- digestion
- metabolism
- excretion
- reproduction
- growth
what necessary life function is first to go when resources are limited?
reproduction
what are the five survival needs?
- nutrients
- oxygen
-water - normal body temperature
- atmospheric pressure
what are examples of positive feedback loops?
giving birth, healing and hemorrhage
what is the process of healing a hemorrhage?
- break or tear occurs in blood vessel
- platelets adhere to site and release chemicals
- released chemicals attract more platelets
- platelet plug forms
what is the purpose of a positive feedback loop?
to intensify the response
what is the purpose of a negative feedback loop?
stimulus that makes something counteract
what is an example of a negative feedback loop?
blood glucose
what is the process of maintaining blood glucose levels?
- stimulus: rising blood glucose level
- high blood glucose level is detected by insulin-secreting cells of the pancreas
- pancreas secretes insulin causing liver cells to take up glucose and store it as glycogen
- as body cells take up blood glucose, glucose levels in the blood decline, and insulin release stops
- return to homeostatic blood glucose level
what are the four types of simple epithelial tissue?
simple squamous, simple cuboidal, simple columnar, and pseudostratified columnar
what are the functions of epithelia?
- protects, covers, and lines organs
- filters
- absorbs nutrients
- sensory input
- secretions/excretions
what are the specialized features of epithelial tissue
- Cellularity—form sheets
• Unique contact points- junctional complexes
• Polarity- gives the cell direction
• Supported by connective tissue
• Innervated, yet avascular
• Capacity to regenerate
what is the structure of simple epithelial tissue?
single cell layer, very thin
what is the structure of stratified epithelial tissue?
multiple cell layers; regenerates from bottom and push apically
what is the function of glandular epithelial?
secretion/export of a particular product
what is the structure of glandular epithelia?
water-based; protein, lipid, or steroid rich substance
what is the function of simple squamous epithelia?
part of the organ
where is simple squamous epithelium located?
lungs and kidneys
what is the function of simple cuboidal?
absorption and secretion
where is simple cuboidal found?
tubular structures
what are the functions of simple columnar?
- absorption of nutrients in digestive system
- secretion
where is simple columnar found?
digestive tract
what is the structure of pseudostratified columnar?
all cells touch the basal membrane, but the nucleus is found at different levels giving the appearance of being stratified; usually ciliated
what is the function of pseudostratified columnar?
secrete mucus and ciliation sweeps things through tubular structures
where is pseudostratified columnar found?
respiratory tract and male reproductive tract
what type of epithelia is often associated with goblet cells?
pseudostratified columnar
what is the structure of stratified squamous?
- thick membrane of multiple cell layers
- basal layers are cuboidal or columnar and are metabolically active
- new cells are pushed to the surface by nutrient sources supplied by underlying tissue
- young cells are pushed towards the surface and cytoplasm is squeezed out, flattening the cell
what is the function of stratified squamous?
increased protection against mechanical damage and chemical stress
where is non-keratinized stratified squamous found?
mouth, esophagus, vagina, rectum
what is the structure of stratified cuboidal?
- occurs (generally) as two cell layers
- cuboidal cells
what is the function of stratified cuboidal?
- protects cell layers
- some absorption and secretion
where is stratified cuboidal found?
- excretory ducts
- sweat glands
- mammary glands
- tubular structures
what is the structure of stratified columnar?
- multiple cell layers
- columnar cells
what is the function of stratified columnar?
- protection
- some absorption and secretion
where is stratified columnar found?
- select parts of respiratory, reproductive, and digestive systems
- some excretory ducts
what is the most rare epithelial tissue?
stratified columnar
what is the structure of transitional epithelium?
- multiple cell layers
- cells dont fall into shape categories
what is the function of transitional epithelium?
- stretches/allows organ stretch
- protection
where is transitional epithelium found?
lines uterus, bladder, and part of the urethra
what do surface cells look like in transitional epithelium?
dome shaped
what shape are the basal cells of transitional epithelium?
cuboidal or columnar
what is the structure of fibers in ligaments and what does this provide?
collagen fibers lie in the direction of force giving great unidirectional strength