Exam 1 Flashcards

1
Q

What happened in 430 BCE wit thucydides?

A

eyewitness account of plaque to promote survival upon future disease occurences

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What happened in the 10th century with rhazes?

A

use of humor theory to distinguish different contagious diseases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What happened in 1000 Ad in china?

A

immunization practiced using crusts of small pox leasions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What happened in 1546 with Girolamo Francastoro?

A

proposed that epidemics are caused by transferal of seed-like entities

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What happened in 11th Century avicenna?

A

refinement of the theory of acquired immunity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What happend in 1720 great britain?

A

inoculation using small pox to prevent smallpox infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What happened in 1796 with Edward Jenner?

A

inoculation with cowpox to prevent smallpox infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What happened in 1862 with ernst haeckel?

A

recognition of mast cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What happened in 1880 with louis pasteur and emile roux?

A

vaccination of chickens against cholera using an attenuated culture of vibrio cholerae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What happened in 1884 with Ilya Machnikov?

A

cellular theory of immunity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What happened in 1890 with Emil von Behring and Shibassaburo Kitasato?

A

theory of humoral immunity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What happened in 1891 with robert koch?

A

discovery of delayed- type hypersensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What happened in 1894 with jules bordet?

A

discovery of the complement system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What happened in 1897 with paul ehrlich?

A

theory of antibody formation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What happned in 1901 with Karl Landsteiner?

A

discovery of A, b, O blood groups

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What happened in 1906 with Clemens von Pirquet

A

term allergy coined

17
Q

What happened in 1932 with alexander gienny?

A

discovery of adjuvants

18
Q

What happened in 1944 with Peter Medawar and Thomas Gibsom?

A

discovery of the immunological basis of transplantation immunology

19
Q

What happened in 1948 with astrid fagraeus?

A

discovery of antibody production occurring in B cells

20
Q

What happened in 1958 with frank McFarlane burnet?

A

development of the clonal selection theory

21
Q

What happened in 1959-1962 with Gerald Edelman and Rodney Porter?

A

determination of the structure of antibodies

22
Q

What happened in 1961-1962 with Jacques Miller?

A

discovery of the thymus involvement in cellular immunity

23
Q

What happened in 1974 with Rolf Zinkernagel and Peter Doherty

A

demonstration of MHC restriction of T cells in their antigen response

24
Q

What happened in 1976 with Susumu Tonegawa

A

ID of somatic recombination of immunoglobulin genes

25
Q

What happned in 1983?

A

discovery of the T-cell antigen receptor

26
Q

What happened in 1990 with david baltimore?

A

discovery of the role of RAG genes in VJ recomination

27
Q

What happned in 1994 with Polly Matzinger?

A

development of the danger model of immunological tolerance, whereby self reactive lymphocytes are deleted from the population