Exam 1 Flashcards
The CNS is made up of the ___
brain and spinal cord
The CNS ____
controls and mediates behavior
The PNS is made up of the ____
somatic, autonomic, and enteric systems
The somatic system ___
controls the cranial and spinal nerves
The autonamic system ___
controls organs and glands, parasympathetic and sympathetic
The enteric system ___
controls the gut
Ramon y Cajal discovered that
neurons don’t actually touch
Synapses are mostly formed as ___
babies and toddlers
Nissyl Staining reveals
cell bodies
Golgi staining reveals
cell bodies + dendrites
Electron Microscope reveals
individual neurons
Multi-photon microscope reveals
detailed images
Glial cells are the ___ of the brain
glue
Ependymal Cell
makes the spinal fluid
Astrocyte
blood brain barrier so toxic substances don’t enter
Micro glial cells
clear waste from the brain
Oligiodendrocytes
make up mylein sheath in CNS
Schwannn cells
make up myelin sheath in PNS
Neurons talk to each other via ___
electrochemical transmission
what are oscilloscopes used to study
electrochemical signals and resting potential
what happens in the depolarization phase
Na+ rushes in and K+ channels open and K+ leaves but slowly
what happens in the repolarization phase
K+ continues to leave to restore membrane potential
When is there an absolute refractory phase
depolarization and repolarization
when is there a relative refractory phase
hyperpolarization
Step 1 of Lifecycle of Neurotransmitter
Synthesized from precursor
Step 2 of Lifecycle of Neurotransmitter
Transported to axon terminal if needed
Step 3 of Lifecycle of Neurotransmitter
Packaged into vesicles
Step 4 of Lifecycle of Neurotransmitter
released via exocytosis after action potential
pros of gap functions (electrical synapse)
fast, bidirectional, does not require a lot of energy
con of gap functions (electrical synapse)
no mechanism for plasticity
pro of chemical synapses
plasticity
con of chemical synapses
slow, requires energy and neurotransmitters
Synapses are the site for ___
neural basis of learning
are inotropic or metabotropic receptors quicker
inotrpic
2 types of Hebbian Learning
habituation and sensitization
Hebbian Learning
connections between a pre and post synaptic neuron will be strengthened following coordinated activity and weakened during uncoordinated activity
Sensitization definition
neurons become more responsive to stimuli with repeated stimulation
How does sensitization work?
repeated stimulus because cAMP causes K+ channels to be less active which causes a longer action potential so more Ca2+ enters the cell during the long depolarization phase so more vesicles of neurotransmitters are released into the synapse which results in larger EPSPs
Habituation definition
neurons become less responsive to stimuli with repeated stimulation
How does habituation work?
repeated stimulus means less Ca2+ is around so less Ca2+ enters the cell, so less neurotransmitters are released into the synapse which results in smaller EPSPs
non associative learning
learning that does not require stimuli association or pairing
3 categories of neurotransmitters
Large Neuropeptides, small molecules, and lipids
Example of a large neuropeptide
opiods
example of lipids
endocannabinoids
3 categories of small molecules
Amino acids, amines, acetylcholine
2 amino acids
glutamate and GABA
2 categories of amines
catecholamines and Seratonin
3 catecholamines
dopamine, epinephrine, and norepinephrine
Glutamate Features
excitatory and involved in learning and memory
Death Mechanism of Glutamate
Glial Uptake