Exam 1

Question 1

What is the Body’s Response to Non/Epinephrine?

Answer 1

⬆️HR, BP, CO
Pupil Dilation
Bronchodilation
GI Motility
Bladder Relaxation
CNS - Alertness

Question 2

What is the Body’s Response to Acetylcholine?

Answer 2

⬇️ HR, BP
pupil constriction
Bronchoconstriction
GI Motility - digest
Bladder contraction
Watery secretion in saliva
CNS - Relaxed, calm

Question 3

Describe the Alpha 1receptor

Answer 3

Located: blood vessels, eyes, bladder , and prostate
When the receptors in vascular tissues constrict, peripheral resistance increases and blood returns to the heart
Circulation is improved and bp is increased

Question 4

Describe the alpha 2 receptor

Answer 4

Located: postganglionic sympathetic nerve endings
When the receptors are stimulated, they inhibit the release of nonepiphrine, leading to the decrease in vasoconstriction, resulting in vasodilation and a decreased bp

Question 5

Describe the beta I receptor

Answer 5

Located: primarily in the heart and kidneys
Stimulation increases myocardial contractility and hr

Question 6

Describe the beta 2 receptor

Answer 6

Located: mostly in smooth muscles of the lungs, gi tract, liver, and uterine muscle
Stimulation causes:
1) relaxation of smooth muscles of Iungs resulting in bronchodilation
2) decrease in gi tone and motility
3) activation of glycogenolysis in the liver increasing blood glucose
4) relaxation of uterine muscles, resulting in a decrease in uterine contractions

Question 7

What are catechlomaines?

Answer 7

Cannot be given orally, have short durations of ‘ action, and cannot cross the blood-brain barrier
Prototype drug: epinephrine, it can activate all four subtypes of andrenergic receptors, therefore it can yield a broadspectrum of symathomimetic effects

Question 8

What are noncatechlomaines?

Answer 8

May be given orally, have longer durations of action, and are able to cross the blood-brain barrier
Phototype drug: albuterol, used to prevent and treat bronchospasms