Exam 1 Flashcards

1
Q

________are the functional units of the brain.

A

Neurons

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2
Q

______ play a supportive role in the brain.

A

Glial cells.

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3
Q

What are the two major cell types that make up the brain?

A
  1. Neurons
  2. Glial Cells
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4
Q

Cajal formulated the Neuron Theory which says_________

A

The cells forming the brain are not continuous with each other. Instead they are individual units

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5
Q

The neuron theory was proposed in opposition to the Reticular theory proposed by Golgi which postulates_______

A

That the brain is one big reticulum (not composed of individual cells) and thus the cytoplasm is a giant syncytium (a single cell or cytoplasmic mass containing several nuclei)

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6
Q

The reticular theory and the neuron theory both were supported using the _________ method

A

Golgi staining method. (Black reaction)

Cajal used a modified version of this method which allowed him to only color parts of the network (these parts were neurons)

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7
Q

What underlies the flow of information in neurons?

A

Polarity

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8
Q

How many types Neurons exist?

A

The number is unknown. It depends on how you classify them.

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9
Q

What are some different ways of classifying neurons?

A

Morphology
Transcription profile
Origin
Function

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10
Q

How many major types of glial cells are recognized?

A

6

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11
Q

Do Neurons undergo cellular division?

A

No. They are in a post-mitotic state

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12
Q

The major parts of a neuron are:

A

Cell body
Axon
Dendrites
Presynaptic sites

Make sure you can identify these on a diagram

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13
Q

Neurons are both _______ and ______ excitable

A

Chemically and electrically

This allows neurons to transform stimuli into electrical signals that can be transmitted over long distances

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14
Q

How do neurons communicate with each other?

A

Synapses

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15
Q

A neuron has both ______ and ________ sites.

A

Presynaptic and post synaptic sites

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16
Q

If neurons differentiated by the number of processes that originate from the cell body, how many types of neurons are there and what are they.

A

4 types:

1) unipolar neurons
2) bipolar neurons
3) pseudo-unipolar neurons
4) multipolar neurons

17
Q

What are unipolar neurons?

A

They have only one process that bifurcates into a dendritic end and an axon an axonal end.

Most neurons in invertebrates are unipolar

18
Q

What is a bipolar neuron?

A

The neurons have two processes that originate from the cell body:
One dendritic structure
One axonal structure

Many sensory neurons in vertebrates are bipolar

19
Q

What are pseudo-unipolar neurons?

A

These neurons initially develop as bipolar cells, but the two cell processes fuse into a single continuous structure that emerges from a single point in the cell body

This type of neuron is found I. The somatosensory system.

20
Q

What is a multipolar neuron?

A

These neurons usually have a single axon and multiple dendritic structures. They vary greatly in shape, especially in the extent, dimensions and intricacy of their branchings.

Most neurons in our brain are multipolar

21
Q

If neurons are categorized by their function, how many types of neurons are there and what are they?

A

3 types:

1) sensory neurons
2) motor neurons
3) interneurons

22
Q

What is a sensory neuron?

A

These neurons detect physical features of the outside world (e.g. a wavelength) and transform these features into electrical signals. They are mostly found in the peripheral nervous system

23
Q

What are motor neurons?

A

These neurons transform electrical signals into behaviors- by regulating muscle tone.

24
Q

What is an interneuron?

A

These neurons connect sensory neurons to motor neurons and integrate/process an electrical signal into a command signal.

Most of the brain is interneurons.

25
The many different ways that neurons can be classified highlights what?
The cellular diversity of the brain
26
True/false: neurons are much like other cells in that they have a nucleus, cytoplasm, organelles and a vacuolar apparatus (ER, Golgi, lysosomes)
True
27
What determines the shape of a neuron?
It’s cytoskeleton
28
What are the three types of cytoskeletal filaments that compose the neuron?
1) neurofilaments 2) microtubules 3) microfilaments
29
What are neurofilaments?
They are the most abundant and most stable cytoskeletal elements in neurons. They are highly stable polymers (~10 nm in diameter) Polymers are made from 3 different subunits: 1) neurofilament L 2) neurofilament M 3) neurofilament H (MLH) Because of their stability, neurofilaments provide strong architectural support.