Exam 1

Question 1

Primary receptor of parasympathetic

Answer 1

Cholinergic

Question 2

Primary neurotransmitter of parasympathetic

Answer 2

Acetylcholine

Question 3

Primary receptor of sympathetic

Answer 3

Adrenergic

Question 4

Primary neurotransmitter of sympathetic

Answer 4

Norepinephrine

Question 5

Direct acting cholinergic agonist

Answer 5

Bethanechol; activates cholinergic receptors causing bladder muscle relaxation

Question 6

Bethanechol SE/AE

Answer 6

tachycardia and hypotension

Question 7

Prototype anticholinergic

Answer 7

Atropine; blocks cholinerguc effects

Question 8

Reversal of atropine

Answer 8

Physostigmine; patenteral only

Question 9

Acetylcholinesterase inhibitors

Answer 9

Donepezil and Galantamine; inhibits acetylcholinesterase from destroying acetylcholine

Question 10

Alpha one adrenergic antagonist

Answer 10

Doxazosin, prazosin, tamsulosin, alfazosin

Question 11

Alpha blockers SE/AE

Answer 11

Orthostatic hypotension, reflex taxhycardia, sexual dusfunction

Question 12

Drug used for extravasation and diagnosing a pheochromocytome

Answer 12

Phentolamine

Question 13

Beta adrenergic anatagonists

Answer 13

Propanolol, metoprolol, labetalol; blocks beta one receptors, reducing cardiac chronotropy and inotropy

Question 14

Beta blocker SE/AE

Answer 14

Fatigue, bradycardia, and hypoglycemia

Question 15

Indication of Alpha blockers

Answer 15

BPH and HTN

Question 16

Indications of Beta blockers

Answer 16

Angina, HTN, HF, Dysrthmias, migraines prevention, anxiety

Question 17

What to assess prior adminestering beta blocker

Answer 17

HR and BP

Question 18

Stimulates aloha one adrenergic receptors resulting in vasoconstriction

Answer 18

Phenylephrine

Question 19

Indications of pheynleprhine

Answer 19

Shock, hypotension

Question 20

Increases two adrenergic effects and reducing symphatetic effects

Answer 20

Clonidine

Question 21

Indication of clonidine

Answer 21

HTN

Question 22

Beta one adrenergic agonist that increased cardiac chronotropy and inotropy effects

Answer 22

Dobutamine and isoproterenol

Question 23

Indication of dobutamine and isoproterenol

Answer 23

Acute decompensated HF; IV only

Question 24

Beta two adrenergic agonist resulting in bronchodilation

Answer 24

Albuterol

Question 25

Beta 3 adrenergic agonist resulting in detrusor smooth muscle relation increasing bladder capacity

Answer 25

Mirabegron

Question 26

SE/AE of mirabegron

Answer 26

Angioedema, HTN, tachy, urinary retention

Question 27

First line for alzheimer's disease

Answer 27

Donepezil, galantamine, rivastigmine

Question 28

Second line for alzheimer

Answer 28

Anti-anxiety

Question 29

Use to treat anticholinergic tox, myastenia gravis and nuero blcoker reversal

Answer 29

Physostigmine

Question 30

Other than physostigmine what other drugs can treat myastenia gravis

Answer 30

Neostigmine and pyridostigmine

Question 31

Increase dopamine synthesis

Answer 31

Levodopa/carbidopa

Question 32

Most effective for Parkinsons disease

Answer 32

Levodopa

Question 33

SE/AE of levodopa

Answer 33

NV, dyskinesia, OH and psychosis

Question 34

has wearing off effect

Answer 34

levodopa

Question 35

activate dopamine

Answer 35

Pramipexole, apomorphine for PD

Question 36

SE/AE of pramipexole and apomorphine

Answer 36

Constipation, nausea, dizzy, drowsy, insomnia

Question 37

Blocks breakdown of dopamine by blocking MAO-B

Answer 37

Selegiline for PD

Question 38

SE/AE for selegiline

Answer 38

Insomnia, no tyramine, administer in the AM

Question 39

Blocks the inactivation of dopamine by blcoking COMT

Answer 39

entacapone for PD

Question 40

serves to reduce the wearing off effect, added to levodopa

Answer 40

Entacapone

Question 41

Treat various severe viruses

Answer 41

Interferon beta 1a

Question 42

Treat mutiple sclerosis

Answer 42

Interferon beta 1b

Question 43

SE/AE of interferon

Answer 43

Flu like, hepatotoxic

Question 44

First line for Multiple sclerosis

Answer 44

Interferon

Question 45

What other drugs are used for Mutiple sclerosis

Answer 45

Monoclonal antibodies and immunosuppressants

Question 46

Drugs used for spasticity

Answer 46

Baclofen, carisoprodol, methocarbamol, and cyclobenzaprine

Question 47

Skeletal muscle telaxant that has anticholinergic effect

Answer 47

Cyclobenzaprine

Question 48

Durgbused for malignant hyperthermia

Answer 48

Dantrolene

Question 49

Black box warning for dantrolene

Answer 49

Hepatotoxic

Question 50

Other indicated used for benzo

Answer 50

Muscle relaxant

Question 51

muscle inactivition

Answer 51

Onabotulinumtoxin A

Question 52

activates GABA

Answer 52

Benzo

Question 53

Drugs under benzo

Answer 53

Lorazepam, diazepam

Question 54

SE/AE of benzo

Answer 54

muscle weakness, hypotension, sedation, muscle relaxant

Question 55

First line for seizure

Answer 55

Benzo

Question 56

Reversal of benzo

Answer 56

Flumazenil

Question 57

Prolong sodium channel inactivation

Answer 57

Phenytoin, fosphenytoin

Question 58

SE/AE of phenytoin and fosphenytoin

Answer 58

Dysrthmia and hypotension

Question 59

Phenytoin can reduce what? And may cause what?

Answer 59

Vitamin K, bleeding

Question 60

Blocks specific calcium channels causes seziure threshold

Answer 60

Ehthosuximide

Question 61

Barbiturates

Answer 61

Phenobarbital

Question 62

SE/AE of phenobarbital

Answer 62

Respiratory depression and sedation

Question 63

For seizure, migraine and bipolar

Answer 63

Valproate

Question 64

Black box of Valproate

Answer 64

Hepatotoxic, teratogenic and pancreatitis

Question 65

Can present with neuro effects upon initial of treatment

Answer 65

Carbamazepine

Question 66

BBW of carbamazepine

Answer 66

SJS/TEN, aplastic anemia, agranulocytosis

Question 67

best option for seizure in pregnancy

Answer 67

Lamotrigine and levetiracetam

Question 68

BBW of lamotrigine

Answer 68

SJS/TEN

Question 69

For post-herpetic neuralgia

Answer 69

Gabapentin

Question 70

Off label for migraine, anxiety and neuropathic pain

Answer 70

Gabapentin