Exam 1 Flashcards
What is preload?
The amount of “stretch” the heart goes through before it gets ready to squeeze.
What is afterload?
The amount of resistance the heart must overcome to open the aortic valve and to push the blood through.
What is CVP (Central venous pressure) ?
The blood pressure in the venae cavae
How do you calculate cardiac output?
HR X SV
What is stroke volume ?
the amount of blood pumped out of the heart during a single contraction
What is ejection fraction ?
The PERCENTAGE of blood that leaves the heart during contraction
Acute Coronary Syndrome
Any condition that is brought on by a sudden reduction or blockage of blood flow to the heart
Tip: Syndrome means not specific
What are manifestations of ACS (acute coronary syndrome)
chest pain/ tightness
SOB
diaphoresis
Dizziness
Radiation of pain
What are risk factors for ACS?
-45+ and male
-postmenopausal women
-African American and Hispanic
-sedentary lifestyle
-Hypertension
-tobacco use
-Hyperlipidemia
-Obesity
-Diabetes
-Family History
-Stress
-Male Pattern Baldness
What is coronary artery disease?
Damage or disease of the blood vessels that supply oxygen to the heart itself.
What is Ischemia
Reduced blood flow
CAD and ischemia relationship
W/ CAD, blood vessels that supply o2 to the heart muscles become damaged or blocked. This leads to ischemia (reduced blood flow to the heart muscles). When blood flow is reduced, O2 is reduced. A reduction in O2 can lead to angina, and eventually MI.
What is an Myocardial infarction (MI)
Complete loss of blood and oxygen to part of the heart. After an MI, tissue death occurs.
What is stable Angina?
“Exertional angina” - anytime someone exerts themselves, they get chest pain.
However, pain is relieved with rest and/or nitroglycerin
What is unstable angina?
Chest pain that is not resolved by resting or taking nitro.
The pain can occur at any time and for any reason (not strictly exertion). This is a sign that MI is imminent.
What is variant angina?
Coronary arterial spasms - this is typically found in cocaine users. The angina comes and goes randomly.
What is a NSTEMI
Non Q-wave MI; only the endocardium is affected
What is STEMI
Most serious form of MI; Necrosis of the entire myocardium
What are the cardiac enzymes that are tested for after a suspected MI
Troponin 1 (this is the first sign of MI). These levels increase after an MI, and it can stay elevated for a few days after an MI
Troponin 2 (this enzyme does not increase during an attack, but shows up later and stays in a persons system for up to two weeks). This can be used as an indicator for long term heart disease.
Creatine Kinase: this is released by muscles that are stressed or dying.
Myoglobin: this is released by muscles that are stressed or dying.
What are the different diagnostic procedures for MI?
ECG (noninvasive)
Echo (noninvasive; basically an ultrasound of the heart)
stress test (exercise or nonexercised)
Thallium Scan (nuclear scan)
What are treatment options for MI
Medication; Anticoagulants, lower cholesterol, lower BP
Cardiac catheterization (angiography)
-invasive non-surgical
-angioplasty
-stenting
Coronary artery bypass graft
-done depending on more severe occlusions
-take a blood vessel from somewhere else and bypass the blockage
What are the two main heart sounds?
S1 = systole: “Lub” (caused by the closing of the mitral and tricuspid valves during contraction)
S2 - Diastole: “Dub” (caused by the closing of the aortic and pulmonic valves during relaxation)
What is a murmur?
Any extra heart sounds outside of S1 & S2; can be caused by turbulence through a valve (whooshing sounds)
What is a systolic murmur?
When the extra sounds happen between the “lub-dub”
“Lub” – “whoosh” – “Dub
What is a diastolic murmur?
when the extra sounds happen outside of the “lub-dub”
“Lub” – “Dub” – “Whoosh”
What type of murmur is more severe, systolic or diastolic?
Diastolic
What is an ejection murmur?
Systolic murmur where blood flow through a narrowed vessel or irregular valve bc the valve is restricted.
What is a regurgitant murmur?
Systolic murmur where backward flow of blood into one of the chambers of the heart (back through a valve that my not have closed)