Exam 1 Flashcards
Sagittal Plane
Right and left halves
Coronal/ frontal
Anterior and posterior
Transverse
Superior and inferior halves
The shaft in long bones
Diaphysis
The diaphysis is made up of
Hard, compact bone
Diaphysis wall
Cortex
Outer surface/membrane of the diaphysis
Periosteum
Contains fatty marrow
Medullary cavity
At each end of the long bone
Epiphysis
Spongy bone or
Cancellous bone
New bone is formed by specialized cells known as
Osteoblasts
Cells that reabsorb old bone are
Osteoclasts
Cortisol bone is stiffer and can withstand greater stress but less
Strain
Bone in a healthy bone will adapt to the loads it is placed under
Wolffs Law
Synovial joints are freely
Moveable
Protein molecule that is attached to many gylcosaminoglycans
Proteoglycan
Tensile strength
Collagen
Most abundant protein in the body
Collagen
Collagen in bone
Shear strength
Collagen in tendons
Tensile strength
How many types of collagen
4
Most abundant collagen in the body
Type 1
Type 1 cartilage is in
Bones, skin, and tendons
Type 2 collagen
Cartilage
Type 3 cartilage
Blood vessels
Type 4 collagen
Sheet like structures
Connective tissue consisting of chondrocytes
Cartilage
3 types of cartilage
Hyaline, elastic, and fibrocartilage
Muscle tissue =
Primary tissue
Skeletal muscles are =
Voluntary
Muscle cells are specialized for
Contractions
Functions of skeletal muscle
Allow us to move, keep posture, layer of protection, and helps maintain temp
Skeletal muscle has 3 layers of
Connective tissue
3 layers of connective tissue in a muscle
Epimysium, perimysium, endomysium
The epimysium surrounds
Collagen and the whole muscle (the outer bag)
The perimysium surrounds
Fascicles
The endomysium surrounds
The individual fibers (deepest)
Muscle fiber bundles
Fascicles
At the ends of muscles (attach muscle to bone)
Tendons
Muscles have extensive
Vascular networks
Skeletal muscle fibers look
Striated
Plasma membrane of muscle fiber
Sarcolemma
What happens when there is a change in membrane potential ?
Muscle contraction (shorten)
Tubes that extend from the surface deep into the sarcoplasm
Transverse T tubules
Transmit action potentials
Sarcolemma
Stripes and multi nuclei
Muscle cells
T tubules bring
Action potentials into the cell
Tubular network surrounding myofibrils
Chambers (terminal cistenae) to T tubules
Sarcoplasmic reticulum
Terminal cisternae and T tubules from a
Triad
Responsible for contraction
Myofibrils
Made up of protein filaments
Myofibrils
Thick and thin filaments are
Microfibrils
Thick filament
Myosin
Thin filament
Actin
Smallest functional unit of muscle fiber
Sarcomere
Dark bands
A bands
Light bands
I
M line
Center of a band , runs vertically, proteins stabilize thick filaments
H band
On either side of m band
Thick filaments only
Where thick and thin filaments overlap
Zone of overlap
I band contains only
Light filaments
Z lines mark the boundaries between
Sarcomeres
Green squiggles
Titin
Elastic protein, tip of thick filament to a line, helps sarcomere stretch back to its normal lengths
Titin
Contain f actin, tropomysosin, and troponin
Thin filaments
Sites to bind myosin
G actin molecules (g= globular)
Troponin blocks
Active sites for binding
Each have a tail and a head
Myosin (hinge allows the head to move)
Sliding Filament Theory
Contraction of muscles, h and I bands narrow , zones of overlap will widen and the z lines move closer together.
Thin filaments must slide towards
The middle of the sarcomere
In order for a muscle to be contracted you need an
Action potential
Space between neuron and skeletal muscle fiber
Neuromuscular joint
Axon terminal of motor neuron releases a
Neurotransmitter
the neurotransmitter that transmits a signal
Acetylcholine
Acetylcholine binds to the blank channel
Na+
Na+ depolarizes the
Motor end plate
The terminal end goes to the
Muscle fiber
Receives the information
Motor end plate
Action potential goes through the
T tubules
The action potential causes calcium to be released from
Sr
Calcium binds to troponin to change
Shape
When the myosin heads have what they are ready
ADP and phosphate
Cross bridge formation
Calcium exposes active sites, myosin heads will bind to the thin filaments
Myosin pulls actin toward
Midline
‘Types of muscle contractions
Isotonic, isometric
Skeletal muscle changes in length
Isotonic
Isometric
There is no change in length
Concentric
Muscle tension exceeds the load , muscle shortens
Concentric example
Raising a dumbbell
Eccentric
Peak tension is less than the load . Muscle will elongate due to contraction of another muscle or gravity.
Ex: lowering a dumbbell
Articulations =
Joints
Where 2 bones meeet, body movement occurs here
Joints
Some joints will have no
Movement
Stronger the joint , the less it will
Move
Structural classification of joint
Fibrous, cartilaginous , bony, or synovial
Functional classifications
Synarthrosis, amphirarthroses, diarhrosis
Immovable joint
Synarthrosis