exam 1 Flashcards
pre term weeks
20-36
full term weeks
> 37
first trimester
1st day of LMP -13w6d
2nd tri
14-27
3rd tri
28w- birth
normal BW
2500-4000g
3 trends in US
increase in preterm
increase in SGA/IUGR babies
increase in high birth weight LGA
the 2 most important predictors for an infants health and survivial is
gest age and birth weight
leading cause of death among neonatal period
congenital abnormalities
major cause of reproductive loss is
genetic and congenital d/os
how many xsomes? how many pairs
22 pairs + x (MOM) and 22 pairs and x or y (DAD)
dominant vs recessive
Dominant: 1 allele (GENE) will cause phenotype to be present
- Recessive: 2 alleles (GENE) required for the phenotype to present itself
aneuploidy
trisomy 21 down syndrome 47 xsomes
turner syndrom
monosomy - missing xsome
who is affected in autosomal dominant
both equally
who is most affected in autosomal recessive
both equally
x linked recessive disorders affect who
men more
when are babies most suseptible to teratogens
first 8 weeks
goal of preconception counseling
make sure couple is in best state of health before counseling
where does fertilization happen
zygote
where does fertilization happen
ampulla of fallopian tube
describe embryonic dev. cascade
Autosomes (body cells) divide by Mitosis.
Gametes (sex cells) divide by Meiosis
union of sperm and ovum form the zygote -< cell division continues to form the morula (16 cells) -> inner cell mass is blastocyst/embryoblast which is the embryo-> outer cell is trophoblast which is the placenta and the implantation occurs 6 days post conception into endometrium
describe implantation
Implantation (embedding of blastocyst into decidua) occurs around day 5 or 6,
generally in upper third of uterus
Once pregnant, endometrium continues to thicken and secrete glycogen.
HCG prohibits further ovulation – this is hormone detected by pregnancy tests
when does heart form
3rd week of gestation
embryonic stage is when
day 15 to week 8
what is embryonic stage
major body organs complete , amniotic sac and fluid and umbilical cord and placenta are formed
what is amniotic fluid
proteins, carbs, lipids, electrolytes, cells, lanugo, vernix
polyhydraminos vs oligohydraminos
poly = > 2L / oligo = <300mL
6 functions of amniotic fluid
cushions fetus
promotes fetal movement
maintains body temp
barrier to infection
promotes lung dev
allows cord to be free from compression
umbilical vein carries
oxygenated blood from placenta to the fetus
umbilical arteries carry
oxygen poor blood from fetus to placenta
what is 3 vessels
1 vein and 2 arteries
placenta is formed by
chorion
placenta function
metabolic -resp, nutrition, excretion and storage
placenta formed by
3rd week from maternal and fetal tissue
placenta becomes fully functional
around 8-10 weeks of gestation
hcg
stimulates corpus luteum to secrete estrogen and progesterone
hcs
preparation of mamillary glands for lactation
relaxin
increases skeletal flexibility
progesterone
supports endometrium and relaxes smooth muscle
estrogen
promotes enlargment and vascularity of organs
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