Exam 1 Flashcards
Three Stages of Prenatal Development
I. Germinal
II. Embryonic
III. Fetal
Duration of prenatal development stages
I. Germinal (0-2 weeks)
II. Embryonic (3-8 weeks)
III. Fetal (9 weeks-birth)
What happens during the duration the germinal stage?
- Zygote is not susceptible to environmental factors
- Fertilization and formation of zygote
- Cell division as zygote falls fallopian tubes
- Stage ends with implantation in the uterine wall
What happens during the duration the embryonic stage?
- Cell migration
(newly formed cells move from the place division occurs to the final destination) - Cell differentiation
(sections of genes (DNA) create proteins that determine what cell type it will become) - Cell “death”
(genetically programmed death of cells (Apoptosis)
(necrosis - cell death caused by trauma)
What stage is the time of the most sensitive period?
Embryonic stage
- A sensitive period
- All major body structures and organ systems are forming, most sensitive to teratogens
What is the support system that develops along the embryo?
- Amniotic sac (protective buffer)
- Placenta (exchange center)
- Umbilical cord
Development occurs from?
From head down (Cephalocaudal)
From center out (Proximodistal)
What happens during the fetal stage?
- Swallowing
- Breathing movements
Fetal movement
5-10 weeks or so: constant movement
10-20 weeks or so: more periodic
20 weeks: 3/4 of time in quiet, active sleep states (REM sleep)
Teratogens
An agent that alters the growth or structure of the developing embryo or fetus; it can cause damage or death during prenatal development
Types of environmental agents
Presence: of an agent that is not typically part of normal development (e.g. drugs, lead, alcohol)
Absence or lack: of environmental input needed for typical development (e.g. folic acid, nutrition)
What are some of the factors that can influence the degree of harm a teratogen will cause?
- Timing of exposure
- Dose-response relation: the amount of exposure
- Individual differences in susceptibility
What are some methodological complications? (In relation to teratogens)
- Sleeper-effects
- Invisible pollutants
- Cumulative risk
What methods are used to examine teratogens on developmental trajectories?
- Observational studies: prospective and retrospective
- Experimental animal studies
What is the most sensitive period of a developing fetus? Why?
Embryonic stage
It is a critical period because it’s the formation of internal and external structures
Thalidomide and importance?
- Medicine used to treat nausea in pregnancy
- Infants were born with limb abnormalities and malformations of organs
- Sensitive period (24-36 after fertilization)
Fetal alcohol syndrome (FASD)
- Fetus is exposed to large amounts of alcohol over a long period of time
Criteria for FASD diagnosis
- Alcohol exposure
- Growth
- Facial characteristics
- Cognition