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PHM 604 > Exam 1 > Flashcards

Exam 1 Flashcards

1
Q

Allergic contact dermatitis treatment

A

Topical corticosteroids (high on thick skin, medium on face no more than 2 weeks)

Calcineurin inhibitors for chronic localized

Systemic cortico for ACD > 20% BSA

Drying agents aluminum acetate

Soothing agents - oatmeal, calamine

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2
Q

Toxicodendron dermatitis posion ivy caused by

A

urushiol

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3
Q

Toxicodendron dermatitis treatment

A 
Prevention
Soothing 
Topical astringents (aluminum acetate)
Topical corticosteroids  high potency 
Systemic corticosteroids

Oral antihistamines

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4
Q

Do topical calcineurin inhibitors work for toxicodendron dermatitis

A

No

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5
Q

Atopic dermatitis is

A

eczema

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6
Q

Eczema caused by

A

filaggrin deficiency

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7
Q

Is atopic dermatitis more likely to affect black children

A

Yes

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8
Q

Mild vs. Moderate vs. Severe atopic dermatitis

A

Mild - itching
Moderate - moderate impact
Severe - losing sleep

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9
Q

Atopic dermatitis treatment mild to moderate disease

A 
Topical corticosteroids 
Low potency (Desonide 0.05%)

High potency cream (Triamcinolone acetonide 0.5%)

Topical calcineurin inhibitors - Tacrolimus 0.03% and 0.1% and pimecrolimus 1%

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10
Q

Severe atopic dermatitis treatment

A 
Soak and smear 
Wet wraps (wet pjs)
coal tar
Dupixent
Cyclosporine
MTX
AZA
MMF
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11
Q

Seborrheic dermatitis is

A

greasy looking yellow scales

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12
Q

Seborrheic dermatitis treatment

A

Topical antifungal agents
Topical corticosteriods
Topical calcineurin inhibitors
Systemic antifungals for severe

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13
Q

Cradle cap treatment

A

Baby shampoo remove scales with soft brush (daily but once resolves q. 2-3)

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14
Q

Bacterial conjunctivitis treatment

A

Erythromycin 5mg/g 1/2 inch qid x 5-7 days

Trimethoprim/polymixin B 0.1% 1-2 gtts qid x 5-7 days

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15
Q

Viral conjunctivitis - pink eye treatment

A

vasoconstrictor

Naphazoline

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16
Q

Permethrin duration

A

apply to damp hair, leave on for 10 mins, wait 7 days to give another

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17
Q

Pyrethin duration

A

apply to dry hair, leave on for 10 mins, repeat in 7 days

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18
Q

How old do you have to be to use DEET

A

< 2 months

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19
Q

For stings use

A

anti histamines

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20
Q

Irritant contact dermatitis treatment

A

topical corticosteroids

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21
Q

Diaper rash consult provider if

A

Fever
Does not improve in 3 days
Blisters or sores

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22
Q

Diaper rash treatment

A

white petrolatum, zinc oxide, paraffin

can try corticosteroids if those don’t work

23
Q

Goals of acne therapy

A

remove keratin plug
reduce inflammatio
reduce sebum production
reduce / eliminate scarring

24
Q

Acne initial therapy

A

topical retinoids

25
Q

Oral isotretinoin names

A

Zenatane, Amnesteem, Claravis, Sotret, Absorica, Absorica LD

26
Q

C/Is for isotrentinoin

A

pregnant
psychiatric conditions
tetracyclines/ doxycycline/minocycline

vitamin A toxicity

27
Q

Dose of isotrentinoin

A
  1. 5 - 1 mg/kg/day

0. 4 - 0.8 mg/kg/day

28
Q

Monitoring isotrentinoin

A

LFT

FLP

29
Q

Maculopapular rash caused by

A

7-10 days starting penicillins, ceph, sulf, anticonvulsants

30
Q

DRESS caused by

A

eosinophilia
delayed onset 1-6 weeks
allopurinol, sulf, barb, phenym, carba, lamotrigine, dapsone

31
Q

DRESS organ involvement treatment

A

0.5-2 mg/kg/day prednisone

32
Q

DRESS non organ involvement treatment

A

High potency topical steroids

33
Q

High potency steroids

A 
Clobetasol 0.05%
Fluocinonide 0.1%
Betamethasone dipro 0.05%
Halobetasol 0.05%
Halcionide 
Other F, beta dip
34
Q

Urticaria is a

A

Type 1 hypersesitivity IgE

35
Q

Serum sickness like reactions

A

urticaria and fever, onset 1-3 weeks after starting drug (pen, ceph, sulf)

36
Q

SJS/TEN

A

life threatening, mucosal surfaces, start with target lesions, onset 7-14 days

37
Q

SJS/TEN risk factors

A

HIV, SLE, malignancy, UV light, HLA

38
Q

SJS/TEN treatment

A

withdraw drug, check cross reacting, supportive care, wound care (chlorhexidine, silver nitrate, silver silfadiazine, gentamicin), opthalmology consult, can try IVIG, systemic corticosteroids, cyclosporine (NO Thalidomide)

39
Q

Hyperpigmentation seen in

A

phenytoin, tetracyclines, silver, mercury, antimalarials, amiodarone

40
Q

Sulfonamide non antibiotics

A 
Loop diuretics
Thiazide diuretics
Sulfonylureas
Sulfasalazine
Dapsone
41
Q

Are 3rd gen cephalosporins cross reactive with penicillins

A

No - just 1st and 2nd gen

42
Q

Normal IOP

A

13

43
Q

Elevated IOP

A

21

44
Q

Types of glaucoma based on IOP

A

NT-glaucoma (normal tension)
Glaucoma
Ocular HTN

45
Q

Glaucoma risk factors

A 
Elevated IOP
Age (>60, >40 blacks)
Family history
race/ethnicity 
increased cup to disc ration (0.2)
Central corneal thickness
ocular perfusion pressure 
T2DM
myopia
46
Q

Goals of glaucoma treatmet

A

drop IOP by ≥25%

47
Q

Best drugs for glaucoma

A 
#1 Prostaglandin analogs 
Beta blockers
Alpha agonists 
Carbonic anhydrase inhibitors 
Rho kinase inhibitors
48
Q

Most efficacious glaucoma drug

A

Bimatoprost or latannprostene bunod

49
Q

First line glaucoma

A

Prostaglandin

BB

50
Q

2nd line glaucoma

A

Dorzolamide
Brimonidine
Brinzolamide, dorzolamide
Netarsudil

51
Q

Who should be treated for ocular HTN

A

elevated IOP and confirmed disc changes/field dfects

risk factors

52
Q

Who should be treated for NT glaucoma

A

field changes
risk factors
documented progression of visual field loss

53
Q

Acute angle closure crisis treatment

A

IV or PO Carbonic anhydrase inhibitor
Topical Beta blocker
Topical Alpha agonist
Topical Pilocarpine

54
Q

Acute angle closure crisis treatment 1 hour no better

A

PO glycerin or isosorbide OR IV mannitol

Ophthalmic steroid

PHM 604 (3 decks)

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