Exam 1 Flashcards
NT for Alzeimers
ACH
NT for Parkinsons
Dopamine
PRIMARY NT for Depression
Serotonin
NTs for Anixety
Serotonin
Gaba
NorEpi
NTs for Schizophrenia
too much dopamine and glutmate
What can happen if you have too little dopamine for antipsychotic drugs?
meds result in loss of dopamine everywhere, tardive dyskinesia
Drugs for psychotic disorders work on what NT?
D2 (dopamine)
IM olanzapine should NOT be used with ______ together and need to be given at least 1 hour apart owing to FDA black box warning, from multiple case reports of cardiopulmonary arrest.
lorazepam
3 meds for emergencies
Haloperidol (Haldol)
Ziprasidone (Geodon)
Olanzapine (Zyprexa)
1st vs 2nd gen antipsychotics- movement disorder?
1st = higher rate EPS/ Tardive (d2) 2nd = Lower Rate of EPS (serotonin +d2)
What special testing/evaluation for we do related to movement for antipsychotic drugs?
AIMS testing
2nd generation antipsychotic has what kind of side effects?
metabolic side effects
Educate/monitor: BMI, Diabetes, weight gain, diet, exercise
Clozapine associated with risk for _______
and requires management within a lab monitoring program
agranulocytosis
What drugs causes neuroleptic malignant syndrome?
All antipsychotic drugs can cause NMS.
*more common in older meds
What can cause neuroleptic malignant syndrome? (aka we need to avoid these things to prevent it from happening)
Take a high doses of medication
Quickly increased doses
IM medications
Switch antipsychotic medications
s/s ofNeuroleptic Malignant Syndrome
High fever(102 to 104 F) Increased respirations Muscle stiffness Sweating Anxiety/changes in mental state Tachycardia Arrhythmia Alterations on blood pressure
- Serious symptoms: Kidney failure Heartand lung failure Hypoxia Aspiration Pneumonia Acidosis
3 NT for depression
Serotonin
Dopamine
Nor Epi