Exam 1 Flashcards
- List three most important properties
of drugs. Which is the most important?
Effectiveness, safety, selectivity.
Effectiveness most important.
What does selectivity mean?
Produces only desired responses for
which it is given.
- List three types of drug names.
Which is the best for communicating
between health professionals?
Chemical, generic, trade
Generic name is the best.
What factor primarily determines
the drug concentration at the receptor?
Administration.
- Pharmacokinetics determines what?
How much of a drug reaches the sites of
action
- List four processes of
pharmacokinetics
Absorption, distribution, metabolism,
excretion
- How does changing the route from
intravenous to oral influence dosage?
Oral dosages are usually higher than
intravenous dosages, because there is a
barrier to absorption.
- Pharmacodynamics refers to what
action?
The nature and intensity of response at its
site of action.
- Name the six rights of safe
medication administration.
Right patient, right drug, right dose, right
route, right time, right documentation
- Explain the difference between a
contraindication and precaution.
A contraindication prevents the drug use
under all but the most severe
circumstances. A precaution increases the
likelihood of an adverse reaction, but not
a life–threatening one.
- The Federal Food, Drug, and
Cosmetic Act of 1938 resulted in what
mandate?
Testing for toxicity
- The Harris-Kefauver Amendment
of 1962 mandated what two
requirements?
Proof of effectiveness and rigorous testing
procedures.
- The Controlled Substances Act of
1970 identified drugs with a potential
for what? What was developed?
Potential for abuse.
Developed Schedules I – V
- Schedule I includes what types of
drugs? Schedule II?
Schedule I- Drugs with no acceptable
medical use and high abuse potential.
Schedule II- Drugs with therapeutic use,
but high abuse potential.
- THE FDA Amendments Act
(FDAAA) of 2007 allowed the FDA
oversight over what?
Safety oversight over drugs that had been
approved. Specifically gave the FDA the
authority to require postmarketing safety
studies, labeling changes to include new
safety information, and restricting the
distribution of drugs with safety concerns.
