Ex Phys Test 3 Flashcards
What are the CV responses to hypoxia?
- Blood volume decreases: plasma volume decreases, respiratory water loss, and increase urine production
- Hematocrit increases: Makes blood more viscous
What is the oxyhemoglobin disassociation curve and what does it mean?
-It’s how saturated the hemoglobin is
-PaO2: pressure of oxygen in the arterials
-SaO2: saturation of oxygen in the hemoglobin
What are the pulmonary responses to hypoxia?
- Pulmonary Ventilation Increases: activation of chemoreceptors, respiratory alkaline, and kidneys excrete more bicarbonate - stabilize pH of blood
- Gas exchange reduced: decrease in gradient and the partial pressure is going to be less than 60 mmHg
What is a hypobaric environment?
high altitude environment which means low overall pressure
What is the significance of the “S Shape” of the oxyhemoglobin curve?
-The flat part is important b/c it resembles a protective mechanism
-Provides a variation for values to be between for PaO2, can have a high saturation for oxygen
-If we drop below 60, then we start to see a big drop in saturation for O2
-Chemoreceptors will jump in and ↑ breathing which ↑ saturation
What are the metabolic responses to hypoxia?
Increased in metabolic rate: increased in thyroxin and catecholamine concentration
Increased food intake to prevent weight loss
Increase reliance on carbs for energy: carbs can be broken down w/o oxygen
Increased sweat evaporation: increase H20 loss
What are nutritional needs for people at altitude?
-Lose of fluids through the skin, respiratory system, and kidneys: increase for dehydration
-Appetite decreases: weight loss over time
-Iron rich foods are recommended: iron deficiency’s may prevent the increase in RBC production
What are totals for air pressure?
Nitrogen: 79%
Oxygen: 21%
Carbon Dioxide: 0.03%
What is air temperature?
gets colder as we go higher in altitude
What is solar radiation?
-increase as we get closer to the Sun
-Easier to get sun-burnt at higher altitude even if it’s cold
What is hypoxia?
oxygen deficiency
How does someone acclimatize to high altitude?
-6-10 days
-Must train at desired intensity and altitude
-A person can acclimatize to high altitude, but can’t fully compensate for hypoxia
What happens to CV when people acclimatize to high altitude?
Max cardiac output ↑ : never reaches sea level values
VO2max ↑ : Goes down and then increases after being in envior., but doesn;t reach sea level values
Resting HR ↓ : higher than sea level values
Max HR ↓ : plateaus lower than sea level value
What happens to Pulmonary when people acclimatize to high altitude?
-Increase in ventilation at rest and during exercise
-With time spent in high altitude ventilation is going to decrease within 3-4 days and levels off but still about 40% higher than sea level at rest
-During exercise ventilation is up, but over time it starts to decrease and then levels off, but still 50% higher
What happens metabolically when people acclimatize to high altitude?
Blood Adaptations:
- Increase in erythrocytes
-EPO increases within 3 hours- return to baseline within a month
-Polycythemia
-Total blood volume increase 10% after 6 months
-People who live at higher altitude have higher hematocrit: percentage of red blood cells is going to be higher than someone at sea level.Their body is used to it which makes their blood more viscous, so they get the benefits of higher red blood cells
What is Blood Doping?
-Athletes take blood out, put it in a freezer and inject before their competition and it’s supposed to input more red blood cells which means you carry more oxygen
-It’s dangerous due to not putting in plasma volume which can lead to blood viscosity
What happens to the Muscle Adaptations when people acclimatize to high altitude?
-If not training correctly, we are going to see a muscle cross-sectional area decrease due to loss of appetite and overall weight loss: This negative effect could not happen as pronounced if we are focusing on eating the right things and since our metabolic rate increases which means we have to increase our food intake to balance that out
-If people do a good job balancing their food intake with their increased metabolic rate, there won’t be as much negative effects on the muscle
-Mitochondrial function and glycolytic enzyme activity reduced: Decreased performance
-Capillary density increases: increase gas exchange
How is Blood Doping compared to altitude training?
-Altitude training you are not taking blood out and injecting blood back in, but you are putting yourself in an environment where you are going to increase red blood cells
-It’s having the same effect except with altitude training your body gets more plasma volume, so it’s less dangerous bc you don;t see that big increase in viscosity that occurs because of it
What are the physiological responses of different types of sports at altitude?
-Endurance:
VO2max decreases as altitude increases
Training at sea level gives advantages
-Anaerobic/ Sprint Exercise:
Minimal demands on oxygen transport system
Generally not impaired; may actually be improved
- Performance might increase bc the air is thinner and therefore air resistance is less
How can you use high altitude as an exercise training stimulus?
-There are more benefits of living at high altitude than training
-People who live at sea level and train at high altitude won’t really get a physiological effect, so it’s not really beneficial for them
-If the exercise event is going to be at high altitude it might help them tolerate it better
-If the event is going to be at high altitude, it’s best to either have the event right away before the effects of altitude can impact their body or they should wait the 7 to 10 days of acclimation before they have their event
What is classical altitude training?
A person will both live and train at high altitude
What are the advantages of using classical altitude training?
-Uses hypoxia as an additional training stimulus
-May cause increase in O2 carrying capacity
-Causes increase in total hemoglobin and RBC mass
What are the disadvantages of using classical altitude training?
1.Athletes may become easily over-trained
-Their body has to work harder to exercise at that high capacity with lower oxygen content
2.Athletes will never be able to train at true VO2max and maxHR!
3.All of the CV variables are going to plateau over time at a value that is less than sea level
-So the athlete may only be able to get to 90 to 95% of their max capacity
What is the training method of living high training low?
A person will live at high altitude but train at sea level
What are the advantages of using the exercise training method living high training low?
- Get benefits of altitude
- Are able to train at true VO2max
- Living at high altitude increases red blood cells, increases blood volume which increase their oxygen carrying capacity and by training at sea level they are able to train at their true VO2max
-Super beneficial for people competing at sea level
What are the disadvantages of using the exercise training method living high training low?
If the competition is at high altitude, then the athlete is not going to have that advantage over their opponents because they are not training at high altitude
What is acute mountain sickness?
Cause: excessive pulmonary hypertension
Signs and Symptoms: headache, mental impairment, inability to sleep, Cheyne Stokes breathing-hyperventilation for a few seconds and then not breathing at all
Treatment: O2 administration, decent- going back to sea level
Prevention: gradually ascending (300m/day)
What are the major male and female sex hormones?
Anterior Pituitary
Testosterone
Estrogen
What does the Anterior Pituitary Gland do?
Stimulates gonads and releases estrogen/progesterone
What does testosterone do?
Increases bone formation: larger bones
-Increase protein synthesis: more muscle mass
-Stimulates EPO: increase red blood cell production
What does estrogen do?
- Broadens pelvis: Females have higher estrogen concentration which is why females have a bigger pelvis
2.Stimulates breast development
3.Increases fat deposition (fat storage)
- Increases LPL activity: lipoprotein is an enzyme that takes the fat out of cholesterol and deposits it somewhere else
5.Increases growth rate of bones: This is why females get larger in size quickly once they hit puberty
What is the relationship between LPL, cholesterol, and fat storage?
- Estrogen increases fat deposition (fat storage),
- Increases LPL activity- lipoprotein is an enzyme that takes the fat out of cholesterol
Why physiologically do women store more fat in their hips and thighs?
LPL activity is high and lipolysis is low
Storage is high and usage is low
What are the differences in strength between males and females?
Females are 40-50% weaker in upper body
Females are 20-30% weaker in lower body
There is a 5-15% difference in relative strength (scaled for body mass)
0% difference in strength when scaled for FFM
Why are there cardiovascular differences between males and females? HR? SV?
Females have higher submax HR
Females have lower SV:
Smaller Hearts: left ventricle and
Smaller blood volume
MaxHR is the same compared b/w males and females
How can women compensate for lower hemoglobin during exercise?
Increase A-VO2diff
Why are there pulmonary differences between males and females? Breathing rate? Tidal volume?
Relative breathing rate is the same
Absolute: women breathe harder:
-They are working at a higher intensity
Females have smaller TV- Tidal Volume
-Smaller lungs
What are the differences in aerobic capacity between males and females?
Average female VO2max is 70-75% of male
Differences occur due to:
-Greater fat mass
-Lower hemoglobin
-Lower max CO
What are the differences in blood lactate response during exercise between males and females?
Same absolute sub max work rate
BL is higher at absolute workload for males than females
LT occurs at the same point when expressed at % of VO2max
How do males and females adapt to training? Are any of these adaptations different?
None of the adaptations are very different
Body Composition: Similar
-Males and female lose/gain weight the same through diet and exercise
Strength: Slight Differences
-Females don’t get big like males but can get strong
-Neuromuscular adaptations more than hypertrophy
CV and Respiratory: Similar
-SV, HR, A-VO2diff, and blood chara. Change the same way
What happens during the menarche phase?
Endometrial lining is shed
What happens during the follicular phase?
Increase in FSH- estrogen production
Stimulate the formation of primary follicle and proliferative growth of uterine lining