ex 1

Question 1

developmental anomalies due to problems with mesenchyme

Answer 1

dystoses

Question 2

dystoses deals with mutations in ______genes

Answer 2

homeobox

Question 3

mutations that deal with bone or cartilage formation

Answer 3

Dysplasia

Question 4

this disorder is due to defective synthesis of type I collagen

Answer 4

osteogenesis imperfecta (brittle bone)

Question 5

mutations in FGFR3

Answer 5

achondroplasia

Question 6

most cases of achondroplasia are (autosomal dominant or spontaneous)

Answer 6

spontaneous

Question 7

short stature, shortening of proximal extremities, frontal bossing

Answer 7

achondroplasia

Question 8

blue sclera occurs in

Answer 8

osteogenesis imperfecta

Question 9

thanatophoric dwarfism is due to

Answer 9

missense or point mutations

Question 10

brown tumor occurs in

Answer 10

hyperparathyroidism

Question 11

absent or incomplete development, supernumerary digits, abnormal fusion of bone

Answer 11

dysostosis

Question 12

Most common congenital malformation of the limbs

Answer 12

syndactyly

Question 13

bullet vertebrae occur in

Answer 13

achondroplasia

Question 14

80% of paget cases involve_______

Answer 14

the axial skeleton or femur

Question 15

most common age paget disease is diagnosed at

Answer 15

70

Question 16

salt and pepper skull & rugger jersey occurs with

Answer 16

hyper parathyroidism

Question 17

what type of fracture is the skin ruptured

Answer 17

compound

Question 18

“bone marrow inflammation”

Answer 18

osteomyelitits

Question 19

most common way that osteomyelitis spreads

Answer 19

hematogenous

Question 20

osteomas MC occur at age

Answer 20

40-50

Question 21

smaller than <2cm, asprin relieves

Answer 21

osteoid osteoma

Question 22

where do osteoid osteomas occur MC

Answer 22

near cortex, proximal femur or tibia

Question 23

osteoblastomas MC occur

Answer 23

spinous or TVP

Question 24

MC primary bone cancer

Answer 24

osteosarcoma

Question 25

3 types of cartilage forming tumors

Answer 25

osteochondroma, chondroma, chondrosarcoma

Question 26

osteochondroma is MC

Answer 26

solitary

Question 27

multiple lesions: chondroma

Answer 27

olliers disease

Question 28

when a chondroma is on the bone surface it is known as

Answer 28

justacortical chondroma

Question 29

produces O-ring sign

Answer 29

chondroma

Question 30

70% of fibrous dysplasias are

Answer 30

monostotic

Question 31

2nd MC pediatric bone CA

Answer 31

ewing sarcoma

Question 32

Primitive neuroectodermal tumor (PNET) show

Answer 32

homer wright rosettes

Question 33

onion skinning

Answer 33

ewing sarcoma