Evidence-Based Surgery (PCS CPGs) Flashcards
Antibiotic prophylaxis for:
Biliary, breast and gastroduodenal surgery
Cefazolin 1g IV single dose
Alt: Cefuroxime 1.5 g IV
Antibiotic prophylaxis for:
Colorectal surgery
- Co-amoxiclav 1.2g IV
- Cefoxitin 2g IV
- Ampi-sul 1.5g IV
Antibiotic prophylaxis for:
CSF shunting
Cloxacillin 1g IV
Alt: Oxacillin 1g IV
Antibiotic prophylaxis for:
Cranial procedures other than CSF shunting
Cefuroxime 1.5g IV
Alt: Cefazolin 1g IV + Genta 80 mg
Antibiotic prophylaxis for:
TCV Surgeries
Cefazolin 1g IV
Antibiotic prophylaxis for:
Orthopedic procedures
Ceftraxone 2g IV
Antibiotic prophylaxis for:
Transurethral resection of the prostrate
Gentamicin 80mg IV within 2 hours before surgery
Antibiotic prophylaxis for:
Elective groin hernia sugery and groin hernia repair
NO prophylaxis recommended!
A TRAP!
in adult patients not undergoing immediate laparotomy, ___ is the imaging modality of choice to determine presence of an intra-abdominal infection.
CT scan
Patient was diagnosed to have a periappendiceal phlegmon. Patient has stable vital signs. Is there room for conservative management, i.e. antimicrobial tx without source control?
HIGHLY selected patients with MINIMAL physiologic derangement and a WELL-CIRCUMSCRIBED focus of infection may be treated conservatively.
Are blood cultures routinely ordered in patients presenting with community-acquired intraabdominal abscess?
NO. They do NOT provide additional clinically relevant information.
Which antibiotic is NOT to be used in the local setting in the management of intraabdominal abscess, due to high resistance rates? Which antibiotics that are traditionally used to cover for anaerobes are NOT recommended locally?
Ampicillin-sulbactam
Aminoglycosides also NOT recommended (too toxic when safer alternatives exist)
NOT recommended anti-anaerobes:
Cefotetan
Clindamycin
What are antibiotics of choice for adult patients with mild to moderate community acquired intraabdominal abscesses?
As single agents: Ticarcillin-clavulanic acid Cefoxitin Ertapenem Moxifloxacin Tigecycline
Combinations of Metronidazole +
Cefax/Cefu/Cefot/Levo/Cipro
For community-acquired infections, do we need to cover for:
- Enterococcus
- Candida
NO!
If the following are isolated in high risk intra-abdominal infections, what is the antibiotic of choice?
- Candida albicans
- Candida albicans in a critically ill patient
- Enterococci
- Fluconazole
- Echinocandins
- Ampi, Pip-Tazo, Vanco