Evidence based medicine Flashcards
1
Q
Aims of UKmi
A
To support safe, effective and efficient use of meds by providing evidence based information and advice.
This service is for healthcare providers
2
Q
No of UKmi enquiries per year
A
300,000
3
Q
Phase 1 trials
A
Generates intial PK/PD info
20-50 participants
Given to the healthy if trt is non toxic or the severely ill if very toxic
Usually only a single dose or a few weeks of treatment
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4
Q
Phase 2 trials
A
Provides exp with trt and administration
<100people
Measures trt efficacy
Short/moderate follow up (few weeks to a year)
Determines daily dosage and trt regimen for P3
5
Q
Phase 3 trials
A
Gives definitive data against a control
Evaluates toxicity/efficacy
500-3000 patients
