Evidence - Based Medicine Flashcards

1
Q

Odds are being expressed in cases
and control

A

ODD RATIO

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2
Q

Comprehensive summary of best evidence
addressing a defined question.

A

Systematic Review

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3
Q

Provide clear and concise, independent
and
evidence-based
recommendations
about patient management that have been
developed by experts.

A

Therapeutic Guidelines

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4
Q

Systematic review uses quantitative methods
to summarize results.

A

META ANALYSIS

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5
Q

EBM Integrated Components

A

Clinical expertise
Patient values
Best evidence

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6
Q

The conscientious, explicit and judicious use of
current best evidence in making decisions about the
care of the individual patient.

A

EVIDENCE - BASED MEDICINE

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7
Q

For quick and selective screening of 1° sources.

A

SECONDARY RESOURCES

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8
Q

Easy access; may be outdated

A

TERTIARY RESOURCES

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9
Q

Most current information

A

PRIMARY RESOURCES

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10
Q

Journals

A

PRIMARY RESOURCES

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11
Q

Textbooks

A

TERTIARY RESOURCES

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12
Q

Less recall bias
Expensive

A

COHORT/PROSPECTIVE STUDY

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13
Q

Presence or absence of risk factors.

A

COHORT/PROSPECTIVE STUDY

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14
Q

Study of the use and effects of drugs in
large number of population.

A

PHARMACOEPIDEMIOLOGY

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15
Q

Disease prevalence and prevalence of risk factors.

A

CROSS-SECTIONAL/PREVALENCE STUDY

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16
Q

Comparing treatment and placebo.

A

RANDOMIZED CONTROLLED CLINICAL TRIALS

17
Q

Presence or absence of disease.

A

CASE CONTROL/ RETROSPECTIVE STUDY

18
Q

Recall bias
Inexpensive

A

CASE CONTROL/RETROSPECTIVE STUDY

19
Q

Types of PHARMACOEPIDEMIOLOGY study design

A
  1. CASE-CONTROL/RETROSPECTIVE
  2. COHORT/PROSPECTIVE
  3. CROSS-SECTIONAL/PREVALENCE
  4. RANDOMIZED - CONTROLLED CLINICAL TRIALS
20
Q

Costly, tlme intensive, ethical considerations

A

RANDOMIZED-CONTROLLED CLINICAL TRIALS

21
Q

Encompasses the
measurement of serum drug
levels and the application of
clinical pharmacokinetics to
improve patient care.

A

THERAPEUTIC DRUG MONITORING

22
Q

The range of drug conc within which the drug exhibits max efficacy and min toxicity in px majority.

A

THERAPEUTIC RANGE

23
Q

Applications of TDM

A

Time to maximal response
Need for loading dose
Dosage alterations
Choosing a formulation

24
Q

gentamicin, tobramycin,
netilmicin, amikacin, vancomycin

A

AMINOGLYCOSIDES

25
Q

Instructions to Pharmacist

A

SUBSCRIPTION

26
Q

Rx Symbol

A

SUPERSCRIPTION

27
Q

Medication prescribed

A

INSCRIPTION

28
Q

Directions to patient

A

SIGNA

29
Q

digoxin, procainamide,
lidocaine, disopyramide, flecainide

A

CARDIOSELECTIVE

30
Q

5mmol/L (required folinic acid)

A

METHOTREXATE (MTX)

31
Q

Lidocaine,Amiodarone (1-25mg/L)

A

ANTI-ARRYTHMIC DRUGS

32
Q

10-20mg/ml

A

PHENYTOIN

33
Q

0.5-2mg/ml

A

DIGOXIN

34
Q

5-20 mg/L

A

THEOPHYLLINE

35
Q

Gentamicin - 1-10 mg/L
Amikacin - 4-12 mg/L

A

AMINOGLYCOSIDES