Everything Flashcards

Question

What is sales - cost of goods sold called? (3 names)

Answer 1

Gross margin, gross profit, manufacturing margin

Answer 2

A plant that grows on another plant that is not parasitic. Ferns, Air plants, and orchids. They grow on tree trunks in tropical rainforests.

Answer 3

Writer of Breaking Bad

Answer 4

Life threatening altitude induced blood clot

Answer 5

Solvency is when you have enough cash to pay for bills, profitability is when your revenue is more than your costs (you can be profitable, but not solvent).

Answer 6

Apollo 11 (Gemini were before Apollo)

Answer 7

Mona Lisa, Vitruvius Man, Last Supper

Answer 8

Humpback: April to December, migrate from Alaska to Hawaii; Gray whales: November to April

Answer 9

Brexanolone (GABAa modulator) now marketed as Zulresso ($7000/vial, $34K for whole treatment), 60 hour infusion required

Answer 10

1. Human genetics 2. Dysregulation or modulation in specific cells or tissues 3. Druggable 4. Effect of drug on pathophysiology 5. Target engagement using biomarker

Answer 11

Tau-PET in the parietal lobe can detect patients who are fast progressors (patients who will convert from MCI to AD)

Answer 12

Used to calculate NPV, like interest, but in reverse. Sometimes called the "hurdle rate" - company's minimum acceptable return

Answer 13

Calculations used to compare cash flows (cash spent and received) at different times in the future.

Answer 14

7M years ago

Answer 15

Interest is tax deductible as a business expense (effective cost of capital is lowered by the 34% expected tax savings) Ex: 10% interest x 66% = 6.6% cost of equity capital

Answer 16

Discounting - process of finding the present value today of cash to be received at some future date.

Answer 17

"Risk free" + "Risk premium" interest rate Risk free - lending return from government bonds Risk premium - based on how risky they determine the business to be

Answer 18

Autonomy of time, tasks, team, and techniques

Answer 19

Cerebral amyloid angiopathy - characterized by amyloid beta in blood vessels in the brain; represent as microvascular lesions (microbleeds and microinfarcts)

Answer 20

1. Autonomy 2. Competence 3. Relatedness

Answer 21

Formatted like a historical financial statement, a proforma shows future financial operations of the company; answers "what might our financial future look like if we make this investment?"

Answer 22

25M years ago

Answer 23

NPV is lower when discount rate is higher (because computed value of future cash flow is lower if discounted more) and NPV is higher when discount rate is lower

Answer 24

FV = PV * (1+i)^y (where i is interest and y is years)

Answer 25

NPV = -Co + Sum(1 to n years){Cy/(1+d)^y} where Co is initial investment and Cy is net cash flow (cash input - cash output for year y); NPV is value that will be added to a business after converting all future cash inflows and outflows into present value; if NPV is positive - add that value to the business, if negative - project should not be pursued.

Answer 26

1. Autonomy 2. Mastery 3. Purpose

Answer 27

PV = FV/(1+d)^y (where d is discount rate per year and y is years)

Answer 28

1. Inflation 2. Risk 3. Opportunity cost

Answer 29

18% (doubling risk after 90), Hypertension and high cholesterol are protective against dementia after 80.

Answer 30

1. Mastery is a mindset 2. Mastery is a pain 3. Mastery is an asymptote

Answer 31

Chimpanzees, Gorillas, Orangutans, Gibbons

Answer 32

Crenezumab - anti-amyloid beta IgG4 mAb (designed to bind Abeta oligomers, lack of vascular amyloid binding and low effector function backbone suggested as reasons for low ARIA risk), Phase III in prodromal or mild AD, Phase II in Mild-moderate AD; Phase III was 4x dose (60mg) as Phase 2 (15mg)

Answer 33

Novartis' newly approved gene therapy for SMA

Answer 34

1. Metalearning - first draw a map (start by learning how to learn the subject of skill you want to tackle. Discover how to do good research and how to draw on past competencies to learn new skills more easily) 2. Focus - Carve our chunks of time you can focus on learning 3. Directness - Learn by doing the thing you want to be good at, do not trade it off for other tasks that are convenient or comfortable 4. Drill - Attack your weakest point, break down complex skills into small parts and build them back together again 5. Retrieval - Test to learn (test before you feel confident) 6. Feedback - Feedback is harsh and uncomfortable, don’t let ego get in the way 7. Retention - Understand what you forget and why, learn to remember things for forever 8. Intuition - Dig deep before building up 9. Experimentation - Explore outside your comfort zone

Answer 35

Divide into why (your motivation) what (the knowledge and abilities you need to acquire - breaking down into concepts, procedures and obstacles that need to be overcome) and how (resources, environment and methods to use)

Answer 36

Expanded CAG repeats coding for polyglutamine (polyQ) tract in the N-terminal region of ataxin-1 SCA1 is an autosomal-dominant neurodegenerative disease - characterized by cerebellar atrophy with severe loss of purkinje cells (ATXN1 alleles with more than 39 uninterrupted CAG repeats can cause SCA1, with tight inverse correlation between length of CAG repeats and age of disease onset. The pathogenic mechanism is mainly driven by gain of function mechanism mediated by the interaction of polyQ-expanded ataxin-1 with its binding parter Capicua (CIC), cognition mechanism is unknown.

Answer 37

1. Concepts - needs to be understood 2. Facts - needs to be memorized 3. Procedures - needs to be practiced

Answer 38

1. Benchmarking (how others have learned skill - research) 2. Emphasize/Exclude method - emphasize and exclude portions of benchmarked curriculum to better direct learning skill for your application

Answer 39

Identify bottlenecks of learning your skill and focus specifically on those parts. Direct-then-drill approach (the cycle of learning) 1. Time slicing - isolate slice in time of a longer sequence of actions (ex few bars in musical piece) 2. Cognitive components - ex for language - grammar, pronunciation, and vocabulary 3. Copycat - copy others’ works or edit your older versions 4. Magnifying glass method - spend more time on one component of the skill than you would otherwise (for when you have to create the whole piece from scratch) 5. Prerequisite chaining - go back to foundational topics if you don’t have prerequisites for learning the skill

Answer 40

Equity: BOD (independent members) - anywhere from 0.25-1% (less for later stage; more for chair (typically 1-1.5% for latter); usually see four year vesting, sometimes with one year cliff and monthly thereafter but often just monthly immediately SAB - typically have seen 0.1-0.25%; rare to see higher than that; vesting may be shorter e.g. 2 years because needs change over time at the company; usually vest monthly starting right away (as I’ve seen for regular consultants) Cash: BOD - $15-30k annually (usually lower end of that); usually don’t see extra for committee work but sometimes do (more usual for public not private companies); more like $30-40k + if independent chair SAB - either hourly rate as advisor ($350-700 depending on seniority/expertise; usually ~ $500); annual retainer ($5-20k, depending on how involved); sometimes a combo (e.g., for 0.1-.0.2% equity, they will charge half usual hourly rate, or take a smaller retainer. SAB chair may be higher

Answer 41

Outcome feedback - right/wrong, but no details Informational feedback - tells you what you are doing wrong, but not how to fix it Corrective feedback - what you are doing wrong and how to fix it (usually only through teacher or mentor)

Answer 42

1. Spacing - Repeat to Remember 2. Proceduralization - make some parts of learning dependent on procedural circuits - conversation, motor function 3. Overlearning - practice core components of skill or go up a level to overlearn initial level 4. Mnemonics

Answer 43

1. Write down the concept or problem you want to understand at the top piece of paper 2. In the space below, explain the idea as if you had to teach it to someone else A. If it is a concept, ask yourself how you would convey the idea to someone who has never heard of it before. B. If it’s a problem, explain how to solve it and crucially - why the solution prosecute makes sense to you. 3. When you get stuck, go back to your book, notes, teacher, or reference material to find the answer

Answer 44

9,941 Fahrenheit | 5600 Celsius

Answer 45

1. Performance drives success, and when performance can’t be measured, networks drive success. 2. Performance is bounded, but success is unbounded 3. Past success x fitness = Future success 4. While team success requires diversity and balance, a single individual with receive credit for the group’s achievements. 5. With persistence, success can come at any time

Answer 46

1997 - Garry Kasparov (world champion in chess)

Answer 47

Cue (make it obvious) Craving (make it attractive) Response (make it easy) Reward (make it satisfying)

Everything Flashcards

(71 cards)