Evaluation of Chest Pain Flashcards
What angina symptom do older ppl. often present with?
dyspnea
who presents w/atypical chest pain?
women, diabetics & elderly
Chest pain: symptoms of 3 other life threatening causes
PE: pleuritic, a/w SOB, hemoptysis, risk factors
Aortic Dissection: ripping or tearing chest pain radiating to back/legs/throat, acute onset, a/w HTN, male, 50-70 years old
Cardiac tamponade: pain worse w/laying down, HYPOTENSION, MUFFLED HEART SOUNDS, JVD, pulsus paradoxus
Chest pain hx (memorize this list of 10)
Onset of pain (gradual or acute) Quality of pain (tearing, burning, stabbing, squeezing, pleuritic) Radiation (shoulder, jaw, back) Site (diffuse, localized) Course (waxing/waning, constant) Associated symptoms (SOB, N/V, hemoptysis, etc.) Risk factors Previous cardiac evaluation? Ever had this type of pain before? Social stressors?
Risk factors for CAD (15)
age gender (M>F) race tobacco use PVD HTN HLD Cancer Diabetes Family history Obesity/physical inactivity Stress Alcohol Illicit drugs Recent travel or surgery
Chest pain: physical exam (6 areas and what to examine there)
General: anxiety, diaphoretic, pale, cyanosis, Levine's sign Neck: JVD, carotid bruits Cardiac: rate, rhythm, murmurs Lungs: wheezing, rales, flail chest Abd: epigastric tenderness Ext: edema, Homan's sign Skin: lacerations, bruising, lesions
Initial dx workup of chest pain
CBC, CMP Cardiac enzymes (Troponin, CK-MB) D-Dimer BNP (if signs of CHF) Cardiac monitoring/telemetry CXR (PA+lateral) EKG (absence of ischemic changes-risk of AMI 4% w/hx CAD, 2% w/out hx CAD)
Stable angina characteristics
- oxygen supply/demand mismatch
- occurs with exercise
- relieved with rest and/or nitroglycerine
Unstable angina characteristics
- more severe, less predictable
- increasing severity/frequency/duration
- occurs at rest
- not relieved with rest and/or nitroglycerin
NSTEMI characterized by
non ST elevation MI
- NON-OCCLUSIVE thrombus
- ischemia with elevated cardiac enzymes
STEMI characterized by
ST elevation MI
- OCCLUSIVE thrombus
- transmural infarction
New LBBB are considered
MI until proven otherwise
Acute Coronary syndrome hx: Onset
gradual & worsens w/exertion, stress
Acute Coronary syndrome hx: time:
ANGINA/ISCHEMIA: <10 min, relieved w/rest
INFARCTION: prolonged & more sever, increasing frequency or constant
Acute Coronary syndrome: quality
discomfort (pressure, heaviness, tightness, fullness, squeezing)
Acute Coronary syndrome: location
substernal or left side chest with radiation to arm, neck, jaw, shoulder, back
NOT related to position or respiration
Most common signs/sxs of ischemic heart dz (8)
- chest pain, pressure, heaviness, tightness, squeezing
- N/V
- diaphoresis
- dyspnea
- palpitations, bradycardia, tachycardia, irregular
- syncope, dizziness
- fatigue
- fluid overload
What is the best test to identify acute myocardial infarction in ED?
12 lead ECG
12-lead ECG: use, goal
single best test to ID AMI in ED
goal: w/in 10 mins of presentation
- still low sensitivity (STEMI, NSTEMI, LBBB, paced rhythms)
- Useful in cardiac risk stratification (normal or nonspecific: 1-5% chance MMI, new ischemia increases the risk to 73%)
Troponins: pros, cons
more specific than CK-MB False positives w/: -sepsis -renal failure -PE (poor prognosis indicator) -subarachnoid hemorrhage
Creatine kinase (total & MB) onset, peak, duration
Onset: 3-12 hrs
Peak: 18-24 hrs
Duration: 36-48 hrs
Troponins: onset, peak, duration
Onset: 3-12 hrs
Peak: 18-24 hrs
Duration: up to 10 days
Myoglobin: onset, peak, duration
Onset: 1-4 hrs
Peak: 6-7 hrs
Duration: 24 hrs
Lactate Dehydrogenase: onset, peak, duration
Onset: 6-12 hrs
peak: 24-48 hrs
duration: 6-8 days
ACS lab studies (other than ECG & enzymes)
CBC, CMP
CWR: cardiomegaly, pulmonary edema
Echocardiography: LV wall thickness/LV enlargement, regional wall motion, valve function/dz, ejection fraction
Nuclear imaging: myocardial perfusion, localizes & quantifies myocardial damage (more expensive)
ACS treatment
IV access cardiac monitoring MONA Morphine Oxygen Nitroglycerin (SL, paste, drip) ASA 325 mg PO
- beta blocker (but NOT if pt is bradycardic)
- unfractionated heparin if indicated
others: ACE-I, CCB, clopidogrel
ACS-reperfusion
PCI, mechanical or pharmacologic:
- coronary angioplasty w/ or w/out stents; atherectomy
- fibrinolytic therapy: streptokinase, tPA, reteplase, tenectoplase
- antiplatelet therapy:glycoprotein IIb/IIA inhibitor (integrelin)
CABG (U) in ppl who can’t be stented
Coronary Artery Bypass Graft (CABG) description
surgical grafting of native blood vessels to bypass obstructed coronaries
CABG: where is it desirable, what is used
desirable for sites of critical flow (LAD)
Saphenous vein graft: superfluous vein from the leg, 50% patent after 10 years
Internal mammary artery graft:
superfluous branch of subclavian artery, remains patent more often than vein
90% patent after 10 years
Aortic Dissection: definition & presentation
severe, acute onset of tearing, sharp or ripping pain radiating to BACK, arms & throat
presentation: UNEQUAL PULSES/BP IN EXTREMITIES, aortic insufficiency murmur
sick appearing: shock, acute HF, CVA/neurologic abnormalities