Eukaryotic genomics - INTRO

Question 1

Functional genomics?

Answer 1

Study of relationship between genotype and phenotype on a genome-wide scale

Question 2

Comparative genomics?

Answer 2

compares genomes of different organisms to learn about gene function and evolution

Question 3

What are approaches used in functional genomics?

Answer 3

• genomics e.g. Whole genome sequencing
• Transcriptomics e.g. RNA-Seq
• Epigenomics e.g. ChIP-Seq
• Translatomics e.g. Ribo-Seq

Question 4

Structural genomics?

Answer 4

Study of complete set of protein structures within a genome

Question 5

Epigenomics?

Answer 5

Study of complete set of epigenetic marks across genome & transcriptione

Question 6

Metagenomics?

Answer 6

Study of complete set of organisms within a sample

identify species within a sample

Question 7

What are elements of protein-coding gene structures?

Answer 7

• promoter
• exon
• intron
• CDS/ORF
• 5’-UTR
• 3’-UTR