Eugenics and CRISPR

Question 1

Who originated the term “Eugenics” ?

Answer 1

Francis Galton

Question 2

What relation was Galton to Darwin?

Answer 2

Cousin

Question 3

What is sterilization?

Answer 3

The process of taking away the ability to have children

Question 4

Who was Carrie’s defense in Buck v. Bell?

Answer 4

Oliver Wendel Holmes Jr

Question 5

Why was Carrie Buck deemed feebleminded?

Answer 5

She was raped at 17 and gave birth out of wedlock

Question 6

Who was Carrie Buck’s mother?

Answer 6

Emma Buck

Question 7

Who were the first people murdered in gas chambers by the Nazi’s?

Answer 7

Disabled children

Question 8

What was the positive change of sterilization in the 1950s?

Answer 8

Became “voluntary”

Question 9

What happened if you were white and wanted to be sterilized?

Answer 9

Denied

Question 10

Why were POC approved for sterilization?

Answer 10

The government wanted a majority of the population to be white (claimed to be the superio race)

Question 11

What happened in Madrigal v. Quilligan?

Answer 11

POC signed for sterilization while giving birth without knowing, violated these women’s rights. The US gov’t wanted to restrict the number of children born (especially those that weren’t white)

Question 12

What does CRISPR stand for?

Answer 12

Clustered, regularly interspaced, short, palindromic repeats

Question 13

What does Cas9 stand for?

Answer 13

CRISPR associated

Question 14

What does tracrRNA stand for?

Answer 14

Trans-activating RNA

Question 15

What does crRNA stand for?

Answer 15

CRISPR RNA

Question 16

How much more efficient is CRISPR than TALENS?

Answer 16

4 times more efficient

Question 17

What are some uses of CRISPR?

Answer 17

Correct genetic defects, treat/prevent the spread of disease, and improve crops

Question 18

What is Cas9?

Answer 18

An enzyme that cuts strands of DNA

Question 19

What does PAM stand for?

Answer 19

Protospacer Adjacent Motifs

Question 20

What do PAM do?

Answer 20

Prevent Cas9 from cutting the DNA randomly

Question 21

What is eugenics?

Answer 21

The self-direction of human evolution

Question 22

What profession did Francis Galton have?

Answer 22

Psychometrist

Question 23

What did Charles Darwin struggle with?

Answer 23

Extreme flatulence

Question 24

What was “race suicide” ?

Answer 24

Teddy Roosevelt coined this term, stating that if you chose not to have children it was a national crime, but if you couldn’t, it was a great misfortune.

Question 25

What did Helen Keller say about Baby Bollinger?

Answer 25

The baby would be an idiot, and it would be a great shame to bring them into the world. The baby shouldn’t be saved, both for its sake and the world’s.

Question 26

Who were other eugenicists?

Answer 26

Alexander Graham Bell, Kelloggs, Planned Parenthood

Question 27

What’s the ranking of feeblemindedness from best to worst?

Answer 27

Moron, High Grade Imbecile, Low Grade Imbecile, Idiot

Question 28

What are the two ways of putting DNA back together?

Answer 28

Gluing, filling the gap with a nucleotide sequence

Question 29

What are the drawbacks of genome editing?

Answer 29

Not 100% effective, “genome vandalism”

Question 30

What was the Central Virginia Training Center?

Answer 30

1910 Eugenics facility. Moved “morons”, the disabled, epileptic, etc. to stop reproducing

Question 31

What’s the difference between Darwin and eugenicists?

Answer 31

Darwin focused on variation, he believed that a lack of variety meant that the population was weak