Etiology of SCI Flashcards
Non-Traumatic Spinal Paralysis
development
structural deformities
congenital malformations
familial paralysis
Non-Traumatic Spinal Paralysis
Development
Development: incomplete closure of the spinal cord: spina bifida with meningocele, meningomyelocele (amount of excrusion through cord and skin)
Non-Traumatic Spinal Paralysis
Structural deformities
- scoliosis, kyphosis, spondylolisthesis,
- ankylosing spondilitis (bamboo spine, i.e. fixed flexed position, spine looses elasticity and the spine doesn’t move and lack of movement can lead to spinal compression)
- Non traumatic, can compromise the spine
Non-Traumatic Spinal Paralysis
Congenital malformation
- –Kippel-Feil Syndrome: hemivertebrae and fusion with adjacent vertebral compression and increased SCI risk.
1. Half the vertebrae fuses with the adjacent vertebrae, this leads to cord compression at that level and a SCI
—Sacralization of the 5th lumbar vertebrae.
Non-Traumatic Spinal Paralysis
Familial Paralysis
Fredrick’s Ataxia (familial paralysis), Spinal Cord Agenesis (spinal cord doesn’t grow in utero or stops growing after birth)
Acquired Spinal Paralysis
- infective
- degenerative
- neoplastic
- vascular
- iatrogenic
- idiopathic
- psychological
Acquired Spinal Paralysis
Infective (4)
1—Bacterial abscess (due to bacterial meningitis)
2—Tubercular Spine = Pott’s Disease (destucction of vertebrae, can damage spine if protrudes inward onto spine)
3—Viral: polio, herpes [neurosyphilis) (can damage spine)
4—Transverse Mylelitis: inflammatory demyelination of a cord segment (often due to infection)
Acquired Spinal Paralysis
Degenerative (3)
1—Disc herniation [disc can herniate into the spinal cord itself lead to damage]
2—Ankylosing spondylitis [degenerative disease]
3—Multiple sclerosis*** [can present just like a spinal cord injury, a spinal cord like syndrome caused by MS differs in fatigue, normally we push patients with SCI but this wont work well in a patient with MS]
Acquired Spinal Paralysis
Neoplastic:
2 types
1—Benign-meningioma, neurofibroma, osteosarcoma [if on the spine can injure cord]
2—Malignant: glioma [cancerous growth of glial cells which are connective tissue of the CNS, it permeates throughout the cord], metastatic myeloma [ie of the vertebral bodies and metastasize into the spine]
Extramedullary SC tumor: Intradural SC tumor: Extradural SC Tumor: Cauda Equina Tumor: Metastatic Tumor: Gliomas: Syringomyelia:
Extramedullary SC tumor:
outside cord
Intradural SC tumor
in dura
Extradural SC Tumor:
outside dura mater, compress the cord
Metastatic Tumor:
can metastisize to the spinal cord
Gliomas:
connective tissue in CNS
Syringomyelia:
hollowed out section of the cord, cavity