Ethers + Epoxide Reactions Flashcards
Show reagents that you could use to prepare the ethers via a Williamson ether synthesis and explain your reasoning:
A Williamson ether synthesis will be more efficient
with a less sterically hindered substrate, since the process involves an SN2 reaction (at the highlighted position shown below). Therefore, in this case, it is better to start with a secondary alcohol and a primary alkyl halide, rather than a primary alcohol and a secondary alkyl halide:
Show reagents that you could use to prepare the ethers via a Williamson ether synthesis and explain your reasoning:
A Williamson ether synthesis will be more efficient
with a less sterically hindered substrate, since the process involves an SN2 reaction (at the highlighted position shown below). In this case, it is better to start with a secondary alcohol and a primary alkyl halide, rather than a primary alcohol and a secondary alkyl halide:
Show reagents that you could use to prepare the ethers via a Williamson ether synthesis and explain your reasoning:
A Williamson ether synthesis will be more efficient
with a less sterically hindered substrate, since the process involves an SN2 reaction (at the highlighted position shown below). In this case, it is better to start with a tertiary alcohol and a methyl halide, rather than methanol and a tertiary alkyl halide:
Show reagents that you could use to prepare the ethers via a Williamson ether synthesis and explain your reasoning:
In order to perform an intramolecular Williamson
ether synthesis, we must choose a starting compound that contains both an OH group and a halogen, as shown here:
Assign a name for the following compound:
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Assign a name for the following compound: