Estrogens Flashcards
Estradiol Ethinyl - Dosage
0.05 and 0.5 mg tablet
Estradiol Ethinyl - Indications
Ovarian failure
Estradiol Ethinyl - Important Tips
One of the most potent oral estrogens
Estradiol Hemihydrate - Brand Name
Vagifem
Estradiol Hemihydrate - Indications
Vaginal atrophy
Estradiol Hemihydrate - Important Tips
Preferred to use at night
Estradiol - Brand Names
Divigel, Estrogel
Estradiol - Indications
Transdermal form of estrogen.
Tibolone - Brand Name
Livial
Tibolone - Dosage
2.5 mg tablets
Tibolone - Indications
Treatment of menopausal vasomotor symptoms
Tibolone - Adverse Effects
Fewer side effects compared to other hormone therapies like breast tenderness
Tibolone - Important Tips
Not available in the USA
Tamoxifen - Brand Name
Nolvadex
Tamoxifen - Indications
Breast cancer, gynecomastia in men with prostate cancer, induction of ovulation
Tamoxifen - Adverse Effects
Hot flashes, increased risk of thromboembolic events, increased risk of uterine cancer
Tamoxifen - Important Tips
Acts as an antagonist in breast tissue and an agonist in the uterus
Raloxifene - Brand Name
Evista
Raloxifene - Indications
Prevention of osteoporosis and reduction of breast cancer risk
Raloxifene - Adverse Effects
Increased risk of thromboembolic events, hot flashes
Raloxifene - Important Tips
Acts as an antagonist in both breast and uterine tissue, unlike tamoxifen
Clomiphene Citrate - Brand Names
Clomid, Ovumid
Clomiphene Citrate - Indications
Induction of ovulation
Clomiphene Citrate - Adverse Effects
Ovarian enlargement, visual symptoms such as blurred vision or double vision, hot flashes, and multiple pregnancy
Clomiphene Citrate - Important Tips
A partial estrogen agonist
Exemestane - Brand Name
Aromasin
Exemestane - Indications
Breast cancer
Exemestane - Adverse Effects
Hot flashes, increased risk of bone fracture and osteoporosis
Exemestane - Important Tips
Should be taken after meals
Anastrozole - Brand Names
Arimidex, Armotraz
Anastrozole - Indications
Breast cancer.
Letrozole - Brand Names
Femara, Letrofem
Letrozole - Indications
Breast cancer
Letrozole - Adverse Effects
Hot flashes, increased risk of bone fracture and osteoporosis
Letrozole - Important Tips
First-line treatment for ovulation induction in PCO patients