Essentials of host - Microorganisms interaction Flashcards
Humans play a substantial role as?
Microbial reservoirs
Acquiring a microorganism from another human serving as the reservoir.
[transmission]
Direct transmission
Can occur when microorganisms from one individual contaminate a vehicle of transmission, such as water (e.g., cholera), that is then ingested by another person.
[transmission]
Indirect transmission
Hospital-acquired, health care— associated, or long-term care — associated infections historically are referred to as?
nosocomial infections
When a human infection results from such an encounter, it is referred to as?
Zoonotic infection
not only survive but also thrive and multiply; Virtheir presence is more persistent.
Resident microbiota
Pathogens, and the characteristics that enable them to cause disease are referred to as?
Virulence factors
2 terms that reflect the degree to which a microorganism is capable of causing disease.
Pathogenicity and Virulence
Specifically refers to the organism’s ability to cause disease.
Pathogenicity
Refers to the measure or degree of pathogenicity of an organism.
Virulence
Organism of high pathogenicity is very likely to cause?
disease
Organism of low pathogenicity is much less likely to cause
infection
Organisms that cause infection when one or more of the host’s defense mechanisms are disrupted or malfunction are known as?
Opportunistic pathogens
Opportunistic pathogens, and the infections they cause are referred to as?
Opportunistic infections
Once surface attachment has been secured, microbial invasion into subsurface tissues and organs (i.e., infection) is accomplished by disruption of the skin and mucosal surfaces by several mechanisms (box 3-3) or by the direct action of an organism’s virulence factors
[microbial virulence factors]
Invasion
Avoid phagocytosis by producing a large capsule that inhibits the phagocytic process.
[microbial virulence factors]
Survival agents inflammation
Toxins are biochemically active substances released by microorganisms that have a particular effect on host cells.
[microbial virulence factors]
Microbial toxins
Microorganisms typically exist as a group or community of organisms capable of adhering to each other or to other surfaces.
[microbial virulence factors]
Biofilm formation
Infectious processes that develop quickly are referred to as acute infections, and those that develop and progress slowly, sometimes over a period of years, are known as
Chronic infections
One of the most effective methods is vaccination, also referred to as
Immunization
[2] two basic approaches to immunization.
Active immunization
Passive immunization
Modified antigens from pathogenic microorganisms are introduced into the body and cause an immune response.
[immunization]
Active immunization
With passive immunization, antibodies against a particular pathogen that have been produced in one host are transferred to a second host, where they provide temporary protection.
[immunization]
Passive immunization
The administration of antibiotics when the risk of developing an infection is high, is another common medical intervention for preventing infection.
Prophylactic antimicrobial therapy
The clues that an infection is occurring are known as?
the signs and symptoms