Essentials of host - Microorganisms interaction Flashcards
Humans play a substantial role as?
Microbial reservoirs
Acquiring a microorganism from another human serving as the reservoir.
[transmission]
Direct transmission
Can occur when microorganisms from one individual contaminate a vehicle of transmission, such as water (e.g., cholera), that is then ingested by another person.
[transmission]
Indirect transmission
Hospital-acquired, health care— associated, or long-term care — associated infections historically are referred to as?
nosocomial infections
When a human infection results from such an encounter, it is referred to as?
Zoonotic infection
not only survive but also thrive and multiply; Virtheir presence is more persistent.
Resident microbiota
Pathogens, and the characteristics that enable them to cause disease are referred to as?
Virulence factors
2 terms that reflect the degree to which a microorganism is capable of causing disease.
Pathogenicity and Virulence
Specifically refers to the organism’s ability to cause disease.
Pathogenicity
Refers to the measure or degree of pathogenicity of an organism.
Virulence
Organism of high pathogenicity is very likely to cause?
disease
Organism of low pathogenicity is much less likely to cause
infection
Organisms that cause infection when one or more of the host’s defense mechanisms are disrupted or malfunction are known as?
Opportunistic pathogens
Opportunistic pathogens, and the infections they cause are referred to as?
Opportunistic infections
Once surface attachment has been secured, microbial invasion into subsurface tissues and organs (i.e., infection) is accomplished by disruption of the skin and mucosal surfaces by several mechanisms (box 3-3) or by the direct action of an organism’s virulence factors
[microbial virulence factors]
Invasion