Essentials + Miscellaneous Flashcards
What is this finding?
What is this for?
It is a Rutherford Morrison Incision. It is a long 20 cm oblique incision that appears to be well healed and no evidence of incisional hernia, pus, erythema, or swelling.
It can be made as a primary incision to provide good access to the right or left colon, retroperitoneum, major vessels (aorta, inferior vena cava and common iliac vessels) and bladder for renal transplantation, colonic resection, caecostomy or sigmoid colostomy.
Note: this is the scar that the skinny female actress has
What is this finding?
What is this for?
Posterolateral Thoracotomy scar
Well healed, no evidence of discharge, no incisional hernia or swelling.
For Lobectomy/pneumonectomy/transplant/biopsy
Note: this is the scar that the male actor has
Give 2 Antiemetics:
Cyclizine (antihistamine)
Odansetron
Give examples of antiplatelets
What is DAPT? What does it include?
What are the indications for DAPT?
Suffix: -grel
Clopidogrel
Ticagrelor
It is Dual antiplatelet therapy which includes Aspirin and a P2Y12 inhibitor
Indications: Acute MI, Stroke, TIA and to prevent Post-op complications of Angioplasty, Stent placement (part of angioplasty), and Coronary artery bypass surgery.
What is the wide bore cannula
Remember the lower the G, the thicker the needle
For wide bore it is 18G or less. Typically they’re referring to the orange needle
When implementing NPO as part of ABCDE management, what is an important piece of history to always be asked?
Note the last time they ate
Anyone going into surgery needs typing and grouping. Clexane (Enoxaparin) is often given as DVT prophylaxis.
What type of drug is Clexane (Enoxaparin)?
How many hours prior to surgery should it be stopped?
It is a LMWH, anticoagulant
It should be stopped 12 hours prior to surgery
How is anticoagulation monitored?
Main way of monitoring is via aPTT. Another way is Factor Xa which is used for LMWH like Clexane but is not as readily available nor monitored.
how is Clexane administered?
Administered Subcutaneously (deep)
How is Unfractionated heparin administered (with dosages)?
If given too much, how would you reverse it?
It can be administered both IV and subcutaneously (very rare). It is administered as a 5,000 IU bolus followed by 1,000 IU infusion afterwards
Reversed with Protamine Sulphate
What are the two types of heparin commonly used?
Discuss the advantages and disadvantages of using each.
What lab finding is associated with both?
Unfractionated:
Advantages: Rapid onset (IV administration) and clearance, !anticoag easily monitored via aPTT!, Can be reversed with Protamine Sulphate, okay in patients with renal failure
Disadvantages: Frequent monitoring required (although easy) and risk of Heparin-induced thrombocytopenia
LMWH:
Advantages: Longer duration of action (sub-cutaneous injection) and lab monitoring typically not needed
Disadvantages: Requires less available Factor Xa monitoring to track coagulation, Contraindicated in renal failure, unknown dosing in morbidly obese patients, not well-reversed with protamine, Heparin-induced thrombocytopenia!
Heparin-induced thrombocytopenia
How do beta blockers work?
What are the main indications for Beta blockers?
Differentiate between selective and non-selective beta blockers giving 2 examples of each.
Explain the main side effects of each type
What are some contraindications?
They inhibit !beta adrenergic receptors! => blocking release of noradrenaline (remember this acts mostly on alpha adrenergic) and adrenaline (acts on alpha and beta where alpha deals with vasoconstriction and beta deals with heart rate and contractility) => inhibit SNS => reduce HR and BP
Indications: Coronary Heart Disease, Compensated Heart Failure, Cardiac Arrhythmias (Sotalol)
Selective Beta blockers (Atenolol, Bisoprolol, Metoprolol)
These drugs are selective for blocking the B1 receptor which is located in the heart.
Side Effects:
Bradycardia and Syncope (hypotension)
Bradyarrhythmia
At higher doses, affects B2 as well
Non-selective: Propanalol, Timolol, Sotalol Acts on B1 and B2
Beta-2 receptors are found in the bronchial tree, blood vessels, and other organs. This broader action leads to bronchoconstriction and vasoconstriction.
Side Effects:
Vasoconstriction and Bronchoconstriction => Contraindicated in PVD/PAD and asthma/COPD
Bradycardia and Syncope (hypotension)
Contraindications: Recent stroke/TIA, Active bleeding, HIT, Uncontrolled hypertension
When palpating the abdomen, what is the difference between rigidity and guarding?
Rigidity is the involuntary tensing of the abdomen that is constantly present
Guarding is the voluntary tensing on palpation due to pain
What is the general initial/immediate management of all surgical emergencies?
1) Admit to hospital
2) ABCDE: Send out FBC w/differentials, U&E, CRP, LFTs, and coag profile, ABG
3) Bowel Rest - NPO for all, NG tube if vomiting, Intubate if GCS 8 or under or if vomiting
4) O2 if in doubt until ABG becomes available (15L 100% O2 via non-rebreather mask)
5) 2x large bore cannulas, IV fluids at 100ml/hr until losses worked out via intake/output chart +/- urinary catheter
6) Type and save, group and hold, Group and cross match 4 units of blood (10 for AAA). If needed give in 1:1:1 aiming for Hb>8 and >10 in CVD
7) Analgesia (Paracetamol, NSAIDS, Morphine/oxynorm/oxycontin)
8) Antiemetics if needed (Ondansetron)
9) Antibiotics: EXCEPT IN PANCREATITIS Coamox/pip taz + Gent/Metronidazole
10) DVT prophylaxis (TEDs, Clexane, LMWH)
What is the triad of ascending cholangitis?
Fever + Rigors
Jaundice
Rigors
MOA of ACE inhibitors
Main indications of ACE inhibitors
Give 2 examples of ACE inhibitors
Give the major side effects
Inhibits Angiotensin (produced by kidney along with renin) converting enzyme which is responsible for converting Ag1 (produced by liver) into Ag2 which then acts to vasoconstrict (in which the drug will cause vasodilation => reduced BP)
Indications: !HTN, HF, Acute MI!, Nephropathy, Coronary heart disease
Examples: Enalapril, Lisinopril, Ramipril
Side Effects: Hypotension (esp first dose), Dry cough (bradykinin buildup), Hyperkalemia, Renal Dysfunction
What is a common side effect of lumbar puncture or spinal anaesthesia other than bleeding, infection, bruising at site or altered sensation.
Post-dural/puncture headache
What are ARBs? give MOA
Give 2 examples
Angiotensin receptor blockers. These block the effect of Ag2 on its receptors => vasodilation and reduced BP
Examples: -sartan
Losartan
Valsartan
What is Nebivolol?
It is the only beta blocker that cause NO-mediated vasodilation (nitrous-oxide). It does this by stimulating the B3 receptors (Ouuu)
What is Sotalol?
What is it’s main indication
Sotalol is a special beta blocker that also blocks K+ channels => Antiarrhythmic effect
What is the drug of choice for a bradyarrhythmia?
Atropine
Give some indications for propanolol?
Cardiac: CHD, HF, Cardiac arrhythmias (better to go with sotalol for arrhythmias)
Other: Essential tremor, Portal hypertension, Migraine prophylaxis, Thyroid storm.
What is the main non-cardiac indication for Timolol?
Glaucoma