Esophagus, Stomach, Spleen and Pancreas Flashcards
Both the ____ esophageal sphincter and ___ esophageal sphincter are closed at rest
upper and lower
Achalasia
Failure of the Lower esophageal sphincter tone to relax during swallowing accompanied with a lack of peristalsis
Barrett Esophagus
Normal squamous epithelium changes to metaplastic columnar epithelium
Chronic exposure to acidic gastric contents – GERD
Chronic alcohol abuse
Smoking
Types of hiatal hernia
Sliding / Type I
Paraesophageal / Type II
Mixed / Type III
Type IV
Acid release in the stomach is mediated by:
Vagal stimulation (acetylcholine)
Gastrin release – G cells in response to gastric distention
Histamine
Peptic Ulcer Disease causes:
Helicobacter pylori bacterium is the major etiologic factor
Overuse of medications such as aspirin and nonsteroidal anti-inflammatory drugs (NSAIDS), and corticosteroids
Excessive alcohol consumption, tobacco use, stress, and receiving radiation therapy can increase one’s risk for peptic ulcers
Most common complications of peptic ulcer disease are
hemorrhage> perforation> obstruction
What are the most effective antisecretory agents for PUD?
Proton pump inhibitors
Most frequent complication of gastric ulceration is _______
perforation
PUD most common cause of ________
hemorrhage
Increased gastric mucosal acidosis is common in :
Critically ill patients
Pt. undergoing prolonged, complex surgical procedure
Pt. undergoing cardiopulmonary bypass
Insulin is eliminated by the _____ and ___ and has an elimination half-life of ____ minutes.
kidneys and liver
5 minutes
Whipple procedure / Pancreatoduodenectomy
complex operation to remove the head of the pancreas, the first part of the small intestine (duodenum), the gallbladder and the bile duct.
Small intestine section lengths:
Duodenum ~ 20cm
Jejunum ~ 100cm
Ileum ~150cm
The three major classes of nutrients that undergo digestion in the small intestine are :
proteins, lipids (fats), and carbohydrates