Esclerose Multipla Flashcards

1
Q

Definição de EM

A

Doença autoimune, desmielinizante do SNC

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2
Q

Epidemiologia

A

Mulheres

Jovens

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3
Q

Quadro clínico

A
  1. Neurite óptica
  2. Sd 1ºNM
  3. Sint sensitivos
  4. Incontinência urinária
  5. Neuralgia do trigêmeo
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4
Q

Doença de Devic

A

Neurite óptica isolada

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5
Q

Anti corpo da neurite óptica isolada

A

Anticorpo anti aquaporina 4 = NMO IgG

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6
Q

Formas clínicas

A

Remitente recorrente 80%
Secundariamente progressiva (era RR)
Primariamente progressiva

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7
Q

Sintoma de Uhthoff

A

Piora dos sintomas com o calor (febre…)

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8
Q

Sinal de Lhermitte

A

Choque na coluna durante a flexão cervical

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9
Q

Diagnóstico?

A

Critérios de McDonald

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10
Q

LCR

A

Bandas oligoclonais de IgG

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11
Q

RNM com contraste

A

Múltiplas placas desmielinizantes

Hipersinais ovalados periventriculares (DEDOS DE DAWSON)

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12
Q

Tto surto

A

Metilpredinisolona 1g EV por 5 dias

Ou plasmaférese

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13
Q

Tto manutenção

A

Betainterferona 1A e 1B
Natalizumabe
Fumarato de dimetila
Fingolimabe

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