ESCHERIHIA COLI, EDEMA DISEASE (ED), POSTWEANING DIARRHEA (PWD) Flashcards
E. coli suolistotulehdus
disease
Escherihia coli, Edema disease (ED), Postweaning diarrhea (PWD)
Edema Disease (ED) is a disease of
weaner and grower pigs
ED is caused by
E. coli
ED is characterized by
subcutaneous and subserosal edema, progressive ataxia, recumbency and death
Postweaning diarrhea (PWD) is a disease of
post weaning period
PWD is caused by
E. coli
PWD is characterized by
diarrhea, dehydration and often death
agent
E. coli
ED strains producing
verocytotoxin (STEC > EDEC)
> O138, O139, O141
PWD specific serotype of
enterotoxigenic E. coli
ED and PWD can occur
separately or at the same time
- intake of pathogenic
E. coli
- adherence and proliferation in
intestine
- _______ destroys blood capillaries, fluid loss
Shiga toxin
- clinical picture
-oedema
-lying on the side
-paddling
-high losses
ED Edema Disease in ….. weaners
4-12 WEEK
ED morbidity
50%
ED sporadic dz most likely affected are the
thriftiest pigs
ED frequently occurs within
1 week after the change of diet, weaning, vaccination, pen change, regrouping
ED outbreak duration average
8 days (< 15 days)
ED … spread to other pens in the same farm
does not
PWD …. after weaning
3-10 DAYS
PWD morbidity
80-90%
PWS mortality (case-fatality)
30%
PWD … spread to other pens in the same farm (within short period of time)
DOES
Transmission: excretion
feces
Transmission mainly via
ingestion
Transmission: route
fecal-oral
clinical signs ED: ….. hindlimbs, falling-earliest and most obvious sign!
incoordination
clinical signs ED: …. of the eyelids and conjunctiva, face
edema
clinical signs ED: …. in 6-36 hours
death
clinical signs PWD: …. of one or two pigs in good condition
sudden death
clinical signs PWD: …. - watery and yellow
severe diarrhea
clinical signs PWD: …., dehydration
fever
clinical signs PWD: … , weight loss
anorexia
clinical signs PWD: … in few days
death
post mortem ED: facial
edema
post mortem ED: full
stomach
post mortem ED: mesenteric
edema
post mortem PWD: de
hydration
post mortem PWD: serofibrinous, perito
nitis
post mortem PWD: fluid-filled
intestines
post mortem PWD: mesenteric
edema
DDx: ED
-aujeszkys disease
-teschrn’s disease
-streptococcal meningitis
-salt or organic arsenic poisoning
DDx: PWD
-edema disease
-swine dysentery
-salmonellosis
-erysipelas
-pasteurellosis
diagnosis: material
-feces
-bipsy (intestines, mesenteric LNs)
Tx: ED: no Tx > toxins allready in
bloodstream and there is no effective Tx
diagnosis: in the lab
-bacteriology-isolation of E.coli
-histology
Tx: PWD: antimicrobials (5-7 days) > ABs in
water (or food)
> electrolytes
