ERV related Flashcards
1
Q
Which ERV products can be recognized by PRRs?
A
ERV-derived dsRNA -> TLR3
Protein: Syncytin-1 protein -> TLR3, HERV-W Env -> TLR4
RNA: HERVK-RNA -> TLR8
dsRNA -> MDA5
dsDNA -> cGAS
RNA-DNA heteroduplex -> TLR9
Which ERV products can be recognized by PRRs?
ERV-derived dsRNA -> TLR3
Protein: Syncytin-1 protein -> TLR3, HERV-W Env -> TLR4
RNA: HERVK-RNA -> TLR8
dsRNA -> MDA5
dsDNA -> cGAS
RNA-DNA heteroduplex -> TLR9