ERV related Flashcards

1
Q

Which ERV products can be recognized by PRRs?

A

ERV-derived dsRNA -> TLR3
Protein: Syncytin-1 protein -> TLR3, HERV-W Env -> TLR4
RNA: HERVK-RNA -> TLR8
dsRNA -> MDA5
dsDNA -> cGAS
RNA-DNA heteroduplex -> TLR9

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