ERS L3-5 Introduction Flashcards

1
Q

Meglitinide

A
Type II diabetes
Inhibit ATP-sensitive K+ channe;
- no K+ efflux
- depolarization
- opening of voltage-dependent Ca channel
- Ca influx
- insulin release by exocytosis
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2
Q

Sulfonylureas

A
Type II diabetes
Inhibit ATP-sensitive K+ channe;
- no K+ efflux
- depolarization
- opening of voltage-dependent Ca channel
- Ca influx
- insulin release by exocytosis
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