ERITROPOYETINA Flashcards

1
Q

MECANISMO DE ACCION DE LA ERITOPOYETINA

A

ESTIMULA LA PROLIFERACION Y MADURACION DE PROGENITORES ERITROIDES COMPROMETIDOS PARA AUMENTAR LA PRODUCCION DE ERITROCITOS

NEMOTECNIA:
PROMA
PROERI

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2
Q

SON ALGUNAS DE LAS INDICACIONES DE ESTE FARMACO

A

ANEMIA SECUNDARIA A INSUFICIENCIA RENAL
ANEMIA CON ENFERMEDADES NEOPLASICAS
ANEMIA EN PACIENTES CON VIH
TRATAMIENTO CON QUIMIOTERAPICOS

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3
Q

FARMACOCINETICA

A

L : LV, SUBCUTANEA*
A: T MAX: 12-18 HRS, F 20%
D: VAD 50 ML/KG, SE CONCENTRA EN HIGADO RIÑONES Y MO
M: HEPATICO
E: ORINA Y HECES, SEMIVIDA DE ELIMINACION 16-67 HRS
I.V 4-13 HORAS
ACCION EN 2-3 SEMANA

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4
Q

EFECTOS ADVERSOS

A

HIPERTENSION, TROMBOSIS VASCULAR, SINTOMAS GRIPALES, SOLORES OSEOS, ESCALOFRIOS, CONVULSIONES

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5
Q

INTERACCIONES RELEVANTES

A

AUMENTO DE SUSTANCIAS DE ACCION HEMATOPOYETICA

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6
Q

CONTRAINDICACIONES DE ERITROPOYETINA

A

HIPERSENSIBILIDAD
HIPERTENSION ARTERIAL NO CONTROLADA
EMBARAZO Y LACTANCIA

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